Workplace Drug Screening Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MSMS)
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Grant Moore Section Head Toxicology Canterbury Health Labs, PO Box 151, Christchurch 8014 grant.moore@cdhb.govt.nz (P27, Thursday 27, Ilott Theatre, 2.00)
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Workplace Drug Screening Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MSMS)
- 1. Workplace Drug Screening Using LCMSMS Grant Moore Workplace Drug Screening Canterbury Health Labs
- 6. Additions to the Standard - 2008
- 9. POCT devices iScreen One step drug card Inverness Medical Sure Step6 Panel cassette Thermo Fisher Scientific Micro Tox Multi Drug Screening Test Branan QuickTox Bio-Rad Tox/See
- 10. Workplace Testing Standard – Immunoassay cut-offs
- 13. Workplace Testing Standard – Confirmation cut-offs
- 15. ABI 3200 Qtrap LCMSMS
- 16. … and after the Earthquake! … it still worked!
- 19. MS Components
- 21. So how does it work? Q1 Q2 Q3
- 22. So how much sample do we need?
- 41. Results – blank samples
- 42. Kronic negative
- 43. Kronic positive
- 46. Kronic selection
- 49. Cannabis End of Cycle report
- 55. POCT EQA Scheme
- 56. Some reflections on the past year!
Notes de l'éditeur
- The material was manufactured by Australian Scientific Enterprises as Human urine specimens 6 linear concentration levels – a low and a high pool with 4 intermediate levels In setting the specifications for all the drugs we used the AS/NZS:4308 standard cut-off limits to offer a range of concentrations from 0ug/L through to significantly above the cut-off value for each drug This year and again in 2011 laboratories can purchase either a 1ml or 10ml vial depending on the sample volume required for analysis The program consists of a single 12 month cycle January through to December and 1 sample per month The program has a specifically designed report for each participant to evaluate their results according to the cut-offs for their device The target values for each drug for every concentration level were set using the standard QAP target setting statistical system suing GCMS and LCMSMS methods