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PRIMER TO PRECOCIOUS
PUBERTY
DR. OM J LAKHANI
CONSULTANT ENDOCRINOLOGIST
www.dromlakhani.com
• Q. What is definition of precocious puberty ?
• Age of onset of puberty 2 -2.5 SD earlier than
normal
• Ie Onset of puberty before 8 years on girls and
before 9 year in boys
• Q. What is the mean age of pubertal onset in
girls and boys and what is 1 SD of both ?
• Mean in girls- 10.5 years
• Mean in boys- 11.5 years
• 1 SD – around 1 year
• Hence 2.5 SD would be 8 and 9 respectively
• Q. What is sequence of pubertal development
in girls ?
1. Thelarche (11-11.5 years)
2. Pubarche
3. Menarche
• Q. And boys ?
1. Increase testicular size
2. Increase penile size
3. Pubic hair
Pearl
• Precocious puberty is more common in girls
• Delayed puberty- more common in boys
Pearl
• With trend for earlier puberty – the cutoffs for
evaluation of precocious puberty are changing
• Hence the patient must be evaluated seeing
the racial and clinical context rather than age
alone
CLASSIFICATION AND CAUSES
• Q. Classify precocious puberty ?
1. Benign / Non progressive variants
2. Central precocious puberty
3. Peripheral precocious puberty
• Q. Which are the benign variants ?
1. Premature thelarche
2. Premature adrenarche (? Pubarche)
3. Isolated premature menarche (controversial)
4. Non progressive Precocious puberty or
Intermittently progressive precocious
puberty
Q. What is isosexual precocity and contrasexual
precocity ?
• Isosexual – early development sexual features
characteristic of the same sex
• Contrasexual – early development sexual
features characteristic of the opposite sex

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PRIMER TO PRECOCIOUS PUBERTY

  • 1. PRIMER TO PRECOCIOUS PUBERTY DR. OM J LAKHANI CONSULTANT ENDOCRINOLOGIST www.dromlakhani.com
  • 2. • Q. What is definition of precocious puberty ?
  • 3. • Age of onset of puberty 2 -2.5 SD earlier than normal • Ie Onset of puberty before 8 years on girls and before 9 year in boys
  • 4. • Q. What is the mean age of pubertal onset in girls and boys and what is 1 SD of both ?
  • 5. • Mean in girls- 10.5 years • Mean in boys- 11.5 years • 1 SD – around 1 year • Hence 2.5 SD would be 8 and 9 respectively
  • 6. • Q. What is sequence of pubertal development in girls ?
  • 7. 1. Thelarche (11-11.5 years) 2. Pubarche 3. Menarche
  • 8. • Q. And boys ?
  • 9. 1. Increase testicular size 2. Increase penile size 3. Pubic hair
  • 10. Pearl • Precocious puberty is more common in girls • Delayed puberty- more common in boys
  • 11. Pearl • With trend for earlier puberty – the cutoffs for evaluation of precocious puberty are changing • Hence the patient must be evaluated seeing the racial and clinical context rather than age alone
  • 13. • Q. Classify precocious puberty ?
  • 14. 1. Benign / Non progressive variants 2. Central precocious puberty 3. Peripheral precocious puberty
  • 15. • Q. Which are the benign variants ?
  • 16. 1. Premature thelarche 2. Premature adrenarche (? Pubarche) 3. Isolated premature menarche (controversial) 4. Non progressive Precocious puberty or Intermittently progressive precocious puberty
  • 17. Q. What is isosexual precocity and contrasexual precocity ?
  • 18. • Isosexual – early development sexual features characteristic of the same sex • Contrasexual – early development sexual features characteristic of the opposite sex