The document discusses the immune system and immunoparasitology. It describes the components of the immune system, including specific and nonspecific immunity. It discusses the organs and tissues involved, such as the thymus and bone marrow. It also describes the different immune cells like T cells, B cells, macrophages, and their roles. Furthermore, it discusses cytokines and mediators involved in immune responses and mechanisms by which parasites evade the immune system.

1. Bismillahirrahmanirrahiim IMMUNOPARASITOLOGI OLEH : Bag.parasitologi FK USK / Dra.Tjut Mariam Zanaria.MS

12. KARAKTERISTIK NATURAL KILER CELL : - MERUPAKAN 15 % DARI LIMFOSIT DARAH - POSITIF U/ CD 16 DAN 56 - SITOTOKSIK U/ SEL YG TERINFEKSI VIRUS - MEMPUNYAI RESEPTOR Iġ G 2 . KILLER CELL - MERUPAKAN SEL YG BERPERAN DALAM ADCC (ANTIBODY DEPENDENT CITOTOXICITY)

15. Efek Kerja Sitokin

16. Mekanisme Kerja Sitokin

17. RESPON IMUN Eliminasi Merubah Metabolisme Kerusakan Jaringan (+) / (-) Mekanisme Biologis “ Benda Asing”

18. T H NK K T C B T S Sitokin Sitokin Antibodi ADCC Antigen APC makrofag Granulosit Respon Imun

19. CD 8 B cell IL-2 cytokines FIGURE 1. Site of Immunomodulation 1. Antigen recognition 2. Stimulation of IL-1 3. Expresion of IL-2 and other cytokines 4. Proliferation and differentiation antigen Y Y Y Y A 1 CD3 glycoprotein Antigen presenting cell MHC-H peptide B IL-2 3 D D C IL-1 2 D D 4 E Plasma cell 4 E Cytotoxic T cell Primed CD4 helper cell Inhibibitor at each step acting as immuno-suppressant agen A. Rh (D) Immune globulin B . Corticosteroids C . ATG, OKT3, anti-CD4 D . Cyclosporine, tacrolimus E . Azathioprine, methotreate, cyclophosphamide, rapamycin, coticosteroids, mycophenolic acid CD4 helper cell

31. TERIMA KASIH ALHAMDULILLAH