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Design and implementation of Clinical Databases using openEHR
1. Tutorial - Design and
Implementation of Clinical
Databases with openEHR
Pablo Pazos Gutiérrez, Koray Atalag, Luis Marco-
Ruiz, Erik Sundvall, Sérgio Miranda Freire
2. 2
Foundations
• Modern Clinical Databases need to ...
– handle many types of information,
– lost of different data structures,
– be flexible and generic,
– consistent, standardized, future-proof (evolution)
• CDBs are difficult to design!
– design is 10% about storing data, 90% about querying, retieve and using data
• To achieve a good design we need to have:
– deep knowledge of clinical record structures
– apply good practices, standards and support generic requirements
– knowledge about different technologies / solutions
3. 3
Agenda
• Clinical Information Requirements
• Clinical Information Organization
• Database Technologies & Features
• openEHR
– goals, information model, knowledge model, data store &
query, versioning & audit
• openEHR Data Storage Techniques
– Relational + ORM
– Hybrid
• Data Querying
5. 5
Minimal Information Set (ISO 18308)
• Related to storage: from the user point of view
– Patient history
– Physical examination
– Psychological, social, environmental, family and self care information
– Allergies and other therapeutic precautions
– Preventative and wellness measures such as vaccinations and lifestyle interventions
– Diagnostic tests and therapeutic interventions such as medications and procedures
– Clinical observations, interpretations, decisions and clinical reasoning
– Requests/Orders for further investigations, treatments or discharge
– Problems, diagnoses, issues, conditions, preferences and expectations
– Healthcare plans, health and functional status, and health summaries
– Disclosures and consents
– Suppliers, model and manufacturer of devices (e.g. implants or prostheses)
• Internally we want more generic information elements
– especially on our database designs
6. 6
Several ways of accessing clinical data
• Related to clinical data querying for clinical usage (patient level):
– Chronological (e.g. to sort medical consultations)
– Problem-Oriented (access data by condition or disease)
• Health records are associated to a health problem
• Each problem evolves until it is solved/inactivated if it is not chronic
– By medical specialty (e.g. cardiology)
– By department, sector, unit or service (e.g. emergency, ICU, ...)
– Episode
• One or many contacts / visits on different dates
• May include hospitalizations
• Associated with a health problem (e.g. asthma attack)
– Access to individual documents or data points
• e.g. all the blood pressure measures for a patient
• There is also Public Health and Epidemiology (population level)
– we had a tutorial about that yesterday: “Enabling Clinical Data Reuse with
openEHR Data Warehouse Environments”
7. 7
Infrastructure Requirements
• Related to user experience and quality
– Be aware of the CAP theorem!
• Scalability (grow maintaining service level)
• High availability (% operational time)
• Transactionality (all or nothing)
– Performance (run forest, run!)
– Concurrency (we all want that resource)
– Audit (what, when, who, where, why, ...)
– Encryption (data at rest)
– Version management (history of changes)
– ...
• We want all!
– We might need to use different technologies
8. 8
Agenda
• Clinical Information Requirements
• Clinical Information Organization
• Database Technologies & Features
• openEHR
– goals, information model, knowledge model, data store &
query, versioning & audit
• openEHR Data Storage Techniques
– Relational + ORM
– Hybrid
• Data Querying
11. 11
Agenda
• Clinical Information Requirements
• Clinical Information Organization
• Database Technologies & Features
• openEHR
– goals, information model, knowledge model, data store &
query, versioning & audit
• openEHR Data Storage Techniques
– Relational + ORM
– Hybrid
• Data Querying
12. 12
DBs for different kinds of usage
• operative / transactional databases (OLTP)
– read/write oriented
– support business processes, small historical data
• querying databases
– read oriented
– read-only data, might be in memory
• document database
– audit, versioning, electronic signature (authenticity, incorruptibility)
• analysis database
– read oriented
– might need ETL
– data linking + data mining + statistical analysis + prediction techniques (trends)
• datawarehouse database
– ETL from many data sources
– batch calculations of indicators over loads of historical data
13. 13
Databases and Data Structures
DBMS Relational XML JSON Key/Value Graph
MySQL native partial in development can be modeled can be modeled
Postgres native complete complete hstore extension hstore extension
Oracle native complete complete NoSQL edition NoSQL edition
SQLServer native complete in development can be modeled can be modeled
eXistDB no native output map map
MongoDB no no native JSON JSON
CouchDB /
Couchbase
no no native JSON JSON
Neo4j can be modeled can be modeled can be modeled can be modeled native
Riak no no store and get native no
15. Consider
many use cases can be met efficiently
by relational databases, but each project is different,
and there is no one-fits-all solution
We are not worried about performance just yet, we’ll focus on
how to design Clinical Databases with openEHR first!
16. 16
First approach
• The choice depends on the context
– use cases, estimated # of operations / # of records, organizational knowledge, ...
• For the operative / transactional DB lets go with a relational database:
– MySQL, Postgres, Oracle, SQLServer, …
– NOT a recommendation: just focusing on one option to understand some
common clinical database design concepts applicable on other technologies.
17. 17
First approach
• Loads of reads? Complex queries and JOINs? Low performance?
– try relational for writes + documental for reads
• Needs ETL: relational => doc (JSON,XML)
– you can denormalize the relational DB, and/or
– use documental capabilities of some RDBs (e.g. Postgres supports XML & JSON)
– made good use of indexes
– analyze query plans (Posrgres / MySQL EXPLAIN query)
• Most systems wont have problems with any of these options
– there is always a way to optimize things!
18. 18
Also, we have transformations between models
• When we need to
– migrate to another technology (e.g. from RDBs to Doc)
– integrate different technologies (hybrid solution)
20. 20 20
Non-RDB-based approaches?
• XML: BaseX, Sedna, eXist, ...
• JSON: Couchbase, CouchDB, MongoDB, ...
• Often suitable if your client side GUI primarily wants XML or JSON
documents/chunks (avoids conversion needs)
…or if you go all-in-javascript on server+client?
• Auto-translating AQL to hierarchy-friendly query languages (e.g. Xquery, N1QL,
Sparql, SQL++?) is often straightforward.
– Consider using a parser generator.
• XML databases fast for transactional (clinical?), but often slow for population-wide
(epidemiology?) queries.
• Solutions such as Couchbase can be very fast for both, after specific indexing is done
(example on next slide).
• Very little is published regarding graph/network databases (Neo4J etc) and object
databases for openEHR usage.
Please test and publish!
21. 21
Scaling? Size & Performance tests, 4.2M patients
Please note:
•All DBs work fine/fast for ”clinical” patient-specific queries, the graph shows population-queries
•the RDB, here used as source and reference, is an epidemiology-optimised non-openEHR-based
reference that we try to match in end-user speed (not size). The XML/JSON based DB-examples have the
flexibility of openEHR to add new archetypes etc. without manually reworking the DB schema etc, the
RDMBs reference example does not have that flexibility.
21
Source: Yet unpublished results, working title: Comparing the Performance of NoSQL Approaches for Storing and Retrieving Archetype-Based
Electronic Health Record Data. Authors: Sergio M Freire, Douglas Teodoro, Fang Wei-Kleiner, Erik Sundvall, Daniel Karlsson, Patrick Lambrix
More about the test data and some of the setup is already published in http://www.ep.liu.se/ecp/070/009/ecp1270009.pdf
Type Databases
Size in GB
sus42k sus420k sus4200k
RDB
MySQL
reference
0.09 0.43 3.6
XML files 1.38 13.8 137.9
JSON files 0.83 8.3 82.9
XML DB
BaseX 1.2 11.9 -
eXist 3.3 - -
Berkeley 3.8 - -
JSON DB Couchbase 0.21 2.1 21
22. 22
Agenda
• Clinical Information Requirements
• Clinical Information Organization
• Database Technologies & Features
• openEHR
– goals, information model, knowledge model, data store &
query, versioning & audit
• openEHR Data Storage Techniques
– Relational + ORM
– Hybrid
• Data Querying
23. 23
• Open Standard to create really flexible, future-proof (maintainable in the long term
at large scale with low cost), interoperable EHRs.
– Defines an Infostructure!
• Created, maintained, tested, validated and implemented by an international
community of professionals.
• The community provides Modeling Tools and Open Source Reference
Implementations in many technologies (Java, Eiffel, .Net, Ruby, Python).
• Key elements:
– technological independence
– multi-level models, clean and complete
• information, clinical concepts, terminology bindings, querying, services, ...
– formal methodology for knowledge management
– open & free access to specifications
• a-la W3C / IETF (enabled the implementation of the Internet and the Web)
• Please join us!
– openEHR Foundation:
• http://openehr.org/community/mailinglists
– openEHR en español:
• http://openehr.org.es
31. 31
Archetypes & ADL
• Represent clinical concepts by constraints over a generic Information Model
– defined in Archetype Definition Language
– globally valid, multi-language
• Important elements for DB design and implementation!
– multi-axial identifier
• openEHR-EHR-OBSERVATION.blood_pressure.v1
– node identifier
• atNNNN
– node path (e.g. path to systolic BP)
• /data[at0001]/events[at0006]/data[at0003]/items[at0004]/value
• archetype id + path
– unique semantic identifier
– will use them in our databases!
• Need archetypes, no problem: http://ckm.openehr.org/
32. 32
Operational Templates (OPT)
• "Big archetypes"
– Combine archetypes to represent clinical documents
– Allows to add more constraints
– Defined in XML
• Use for specific contexts
– one language
– locally valid (organization, federation, national)
• Used by EHR/EMR software directly
– for validating data
– for generating UIs
– for indexing data
– for querying
– …
34. 34
Information & Metadata
• Link between Archetypes and the Information Model
– Will use those fields in our persistence model
– Are important for queries!
References to
Archetypes
and Templates
(semantic content
definitions)
35. 35
Agenda
• Clinical Information Requirements
• Clinical Information Organization
• Database Technologies & Features
• openEHR
– goals, information model, knowledge model, data store &
query, versioning & audit
• openEHR Data Storage Techniques
– Relational + ORM
– Hybrid
• Data Querying
37. 37
openEHR Data Storage Design
• openEHR doesn't define how to store data
– The IM is not a Persistence Model
– The Persistence Model will depend on requirements and technologies
• Our work is to adapt the IM to our persistence needs
• We can simplify, adapt or use part of it (openEHR is very flexible)
– openEHR doesn't care about how we store data but does care about:
• structural and semantic consistency (defined by archetypes & OPTs)
• processable / accessable / queryable data
• Tips:
– archetype id, path, template id, node id are important for querying
– references can be simplified (OBJECT_REF) (FKs in Relational)
– structured data can be simplified (ej. DV_CODED_TEXT)
– …
39. 39
Identity in Object-Oriented Model
• Objects have an identity to:
– differentiate between objects of the same class
– reference those objects
• In the relational model we have Primary Keys
• Solution:
– add an "id" column in each table
– of type "int" or "long" and use it as PK
– FKs reference only PKs "id"
• represents relationships in the OO model
40. 40
Data Type Mapping
MySQL Postgres SQLServer Oracle
Date
date
datetime
date
timestamp
date
datetime2
date
datetime
String
varchar
text
varchar
text
varchar
nvarchar
varchar2
nvarchar2
clob
Boolean bit boolean bit char(1) CHEK IN ('1','0')
Integer integer numeric int number
... ... ... ... ...
Each type we use in the OO model, should be mapped
to a type in the DBMS we chose.
43. 43
Mapping Inheritance
TIP: on table per class, is
better to use the same
value for "id" for the
columns of the same
instances distributed in
different tables.
47. 47
Hybrid approach
• Considerations
– Use only if it makes sense!
• for example if it improves querying performance / scalability
– Modern Relational DBMS compete with some NoSQL features:
• support documents
• scale through clusters
• some allow in-memory tables or views
48. 48
Agenda
• Clinical Information Requirements
• Clinical Information Organization
• Database Technologies & Features
• openEHR
– goals, information model, knowledge model, data
store & query, versioning & audit
• openEHR Data Storage Techniques
– Relational + ORM
– Hybrid
• Data Querying
50. 50
Archetype Query Language
• AQL is like SQL for EHRs
• Archetype ID is "like" a table (type of info we want)
– openEHR-EHR-OBSERVATION.blood_pressure.v1
• Data points identified by paths, "like" "columns (defined by each archetype)
– Systolic BP: /data[at0001]/events[at0006]/data[at0003]/items[at0004]/value
SELECT
obs/data[at0001]/events[at0006]/data[at0003]/items[at0004]/value/magnitude,
obs/data[at0001]/events[at0006]/data[at0003]/items[at0005]/value/magnitude
FROM
EHR [ehr_id/value=$ehrUid] CONTAINS
COMPOSITION [openEHR-EHR-COMPOSITION.encounter.v1] CONTAINS
OBSERVATION obs [openEHR-EHR-OBSERVATION.blood_pressure.v1]
WHERE
obs/data[at0001]/events[at0006]/data[at0003]/items[at0004]/value/magnitude >= 140 OR
obs/data[at0001]/events[at0006]/data[at0003]/items[at0005]/value/magnitude >= 90
Get high BP data
https://openehr.atlassian.net/wiki/display/spec/Archetype+Query+Language+Description
51. 51 51
AQL - Query samples
Marco-Ruiz L, Moner D, Maldonado JA, Kolstrup N, Bellika JG,
Archetype-based data warehouse environment to enable the reuse of
electronic health record data, International Journal of Medical Informatics
(2015), http://dx.doi.org/10.1016/j.ijmedinf.2015.05.016
SELECT o/data/events/data/items[at0078.13]/value AS WhiteCellCount
FROM EHR e
CONTAINS COMPOSITION c [openEHR-EHR-
COMPOSITION.encounter.v1]
CONTAINS OBSERVATION o [openEHR-EHR-
OBSERVATION.lab_test_full_blood_count.v1]
WHERE o/data/events/data/items[at0078.13]/value > 11000000000
AND o/data/events/data/items[at0078.13]/value < 17000000000
TIME WINDOW P1Y/2014-02-12
52. 52 52
AQL - Query samples
Marco-Ruiz L, Moner D, Maldonado JA, Kolstrup N, Bellika JG,
Archetype-based data warehouse environment to enable the reuse of
electronic health record data, International Journal of Medical Informatics
(2015), http://dx.doi.org/10.1016/j.ijmedinf.2015.05.016
SELECT o/data/events/data/items[at0078.13]/value
AS WhiteCellCount
FROM EHR e
CONTAINS COMPOSITION c [openEHR-EHR-
COMPOSITION.encounter.v1]
CONTAINS OBSERVATION o [openEHR-EHR-
OBSERVATION.lab_test_full_blood_count.v1]
WHERE
o/data/events/data/items[at0078.13]/value >
11000000000
AND o/data/events/data/items[at0078.13]/value <
17000000000
TIME WINDOW P1Y/2014-02-12
54. 54
AQL in action
Infectious diseases monitoring at UNN:
• Laboratory tests are extracted from the
LIS in a canonical XML format
• Canonical extracts are transformed into
openEHR compliant extracts
• Extracts are loaded into an openEHR data
warehouse (Think!EHR)
Marco-Ruiz L, Moner D, Maldonado JA, Kolstrup N, Bellika JG,
Archetype-based data warehouse environment to enable the reuse of
electronic health record data, International Journal of Medical Informatics
(2015), http://dx.doi.org/10.1016/j.ijmedinf.2015.05.016
55. 55
Marco-Ruiz L, Moner D, Maldonado JA, Kolstrup N, Bellika JG,
Archetype-based data warehouse environment to enable the reuse of
electronic health record data, International Journal of Medical Informatics
(2015), http://dx.doi.org/10.1016/j.ijmedinf.2015.05.016
56. 56 56
SELECT count(o1/data[at0001]/events[at0002]/data[at0003]/items[at0022]) -- count (patientId)
FROM EHR e
CONTAINS COMPOSITION c
CONTAINS (OBSERVATION o1[openEHR-EHR-OBSERVATION.micro_lab_test.v1])
WHERE (
o1/data[at0001]/events[at0002]/data[at0003]/items[at0010]/items[at0043]/items[at0036]/value = 'Kikhoste'
AND
o1/data[at0001]/events[at0002]/data[at0003]/items[at0010]/items[at0043]/items[at0037]/value='Positiv'
) AND
o1/data[at0001]/events[at0002]/data[at0003]/items[at0024]/value >= '2013-01-04' AND
o1/data[at0001]/events[at0002]/data[at0003]/items[at0024]/value < '2013-01-05'
Marco-Ruiz L, Moner D, Maldonado JA, Kolstrup N, Bellika JG,
Archetype-based data warehouse environment to enable the reuse of electronic health record data, International Journal of Medical Informatics (2015),
http://dx.doi.org/10.1016/j.ijmedinf.2015.05.016
AQL 1:
+ Count positive tests of Pertussis for the day specified in the parameter
AQL in action
57. 57 57
SELECT
count(o1/data[at0001]/events[at0002]/data[at0003]/items[at0022]/value)
FROM EHR e
CONTAINS COMPOSITION c
CONTAINS (
OBSERVATION o1[openEHR-EHR-OBSERVATION.micro_lab_test.v1] AND
OBSERVATION o2[openEHR-EHR-OBSERVATION.micro_lab_test.v1]
)
WHERE (
o1/data[at0001]/events[at0002]/data[at0003]/items[at0010]/items[at0043]/items[at0036]/value =
'Salmonella' AND
o1/data[at0001]/events[at0002]/data[at0003]/items[at0010]/items[at0043]/items[at0037]/value =
'Positiv'
) AND
o1/data[at0001]/events[at0002]/data[at0003]/items[at0020]/value = '1917' AND
o1/data[at0001]/events[at0002]/data[at0003]/items[at0024]/value >= '2013-01-01' AND
o1/data[at0001]/events[at0002]/data[at0003]/items[at0024]/value < '2013-01-15'
Marco-Ruiz L, Moner D, Maldonado JA, Kolstrup N, Bellika JG,
Archetype-based data warehouse environment to enable the reuse of electronic health record data, International Journal of Medical Informatics (2015),
http://dx.doi.org/10.1016/j.ijmedinf.2015.05.016
AQL 2:
+ Count patient ID
+ Salmonella cases in the specified municipality (same as patient just confirmed)
+ In the first 2 weeks of January
AQL in action
61. 61
Path-based queries in action
Results:
+ in XML (or JSON if specified on the query or as a parameter)
+ just the index, no data, get a document using the index or change the query to get the data
<list>
<compositionIndex id="8">
<archetypeId>openEHR-EHR-COMPOSITION.signos.v1</archetypeId>
<category>event</category>
<dataIndexed>true</dataIndexed>
<ehrId>11111111-1111-1111-1111-111111111111</ehrId>
<startTime>2015-08-14 03:06:44.0 EDT</startTime>
<subjectId>11111111-1111-1111-1111-111111111111</subjectId>
<templateId>Signos</templateId>
<uid>e152b2c2-7dbe-44b6-9ec6-2cd698561140</uid>
</compositionIndex>
<compositionIndex id="9">
<archetypeId>openEHR-EHR-COMPOSITION.signos.v1</archetypeId>
<category>event</category>
<dataIndexed>true</dataIndexed>
<ehrId>11111111-1111-1111-1111-111111111111</ehrId>
<startTime>2015-08-14 03:07:06.0 EDT</startTime>
<subjectId>11111111-1111-1111-1111-111111111111</subjectId>
<templateId>Signos</templateId>
<uid>f0a8d192-0f68-4501-8373-f954a47a7385</uid>
</compositionIndex>
...
</list>
62. 62
Path-based queries in action
{
"uid": "70764d85-4e4b-4548-8f71-3a294f35e704",
"name": "Vital Signs",
"format": "json",
"type": "datavalue",
"group": "path",
"projections": [
{
"archetypeId": "openEHR-EHR-OBSERVATION.blood_pressure.v1",
"path": "/data[at0001]/events[at0006]/data[at0003]/items[at0004]/value"
},
{
"archetypeId": "openEHR-EHR-OBSERVATION.blood_pressure.v1",
"path": "/data[at0001]/events[at0006]/data[at0003]/items[at0005]/value"
},
{
"archetypeId": "openEHR-EHR-OBSERVATION.body_temperature.v1",
"path": "/data[at0002]/events[at0003]/data[at0001]/items[at0004]/value"
},
{
"archetypeId": "openEHR-EHR-OBSERVATION.body_weight.v1",
"path": "/data[at0002]/events[at0003]/data[at0001]/items[at0004]/value"
},
{
"archetypeId": "openEHR-EHR-OBSERVATION.pulse.v1",
"path": "/data[at0002]/events[at0003]/data[at0001]/items[at0004]/value"
},
{
"archetypeId": "openEHR-EHR-OBSERVATION.respiration.v1",
"path": "/data[at0001]/events[at0002]/data[at0003]/items[at0004]/value"
}
]
}
Path-based:
+ Get clinical data for all vital signs measures
+ Result in JSON format, grouped by path (type of data)
JSON
expression of
EHRServer
queries
63. 63
GastrOS – Endoscopy Database
http://gastros.codeplex.com
• Open Source openEHR implementation of a commercial DB for academic
research (2011)
• Based on Minimal Standard Terminology for Digestive Endoscopy (MST 2)
• Works with openEHR RM directly
– C# openEHR.NET (Open Source)
– Uses 3 Templates (EGD, Colonopscopy, ERCP)
• Used RDMBS (MS Access and SQLite)
• Uses ORM (Nhibernate) to store XML Compositions
63
70. 70
A Standards-based Approach to Development of
Clinical Registries -
NZ Gestational Diabetes Registry Pilot
Dr. Koray Atalag MD, PhD, FACHI (National Institute for Health Innovation)
Aleksandar Zivaljevic, PhD candidate (Univ. Of Auckland)
Dr. Carl Eagleton MBChB, FRACP (Counties Manukau District Health Board)
Karen Pickering (Diabetes Projects Trust)
71. 71
GDM Registry Database
• Used OceanEHR Framework
– Academic license from Ocean Informatics
– Simplifies persistence and querying plus more!
– Supports openEHR Demographic IM
– Supports AQL
• Extended MultiPrac App (Source provided on academic license)
– MVC Application (VS 2010 w/ SQL Server)
– Handles user management, basic admin etc.
– Supports reference sets, provider/organisation etc.
71
75. 75
Make your own or reuse existing openEHR persistence?
• Open reusable openEHR persistence & query APIs have been suggested and
are now being formally specified
– Join the REST discussion, openEHR wiki + mailinglists
https://openehr.atlassian.net/wiki/display/spec/openEHR+REST+APIs
– Implementations of openEHR SOAP interfaces exist.
• A SOAP API could be formally specified if there is enough interest
– Other API options?
• New reusable implementations are welcome!
• Before implementing your own persistence, consider:
– Is your main interest storage or clinical application?
– Would AQL be helpful in some of your use-cases?
– In what way will it need to scale?
75
76. 76
Conclusion
• openEHR doesn’t specify how to store openEHR clinical data
– not bound to any technology or modeling technique
• Remember to model data with references to metadata
– archetype id, template id, path, node id
• Use operational templates in software, not archetypes directly
– archetypes are too generic, too many options, not so good for software
• Choosing a technology is on you
– there is no one-fits-all solution
– you might need to mix technologies (hybrid solution)
• Modify the openEHR Information Model
– to create your storage model using the chosen technology
• Design generic query mechanisms based on archetype ids and paths
– go for AQL support if you need it, allows to share queries between openEHR Clinical Data
Storages
• Designing and querying Clinical Databases is hard!
– now you have some pointers on where to start
types of information: clinical, demographic, administrative, financial, accounting, ...
good design: we will try to share knowledge on the 3 areas mentioned.
General ideas of the information we need to store and the most common ways to query it.
What information we need to store, from the point of view of the end user.
The message here is we’ll need a generic and flexible solution to store that information and other information that appears in the future without changing the whole database schema/structure (A.K.A future proof database)
The most common ways of querying clinical data and documents, it is also related on the way the information is organized in real life and in the persistence model.
What we need to provide to the end user
We want all of these! and we might need to mix different technologies to be close to a one-fits-all solution, but adapted to our own context/requirements, since there is no such thing for all the contexts, CAP is why we don’t have such thing.
Transactionality: Atomicity on transactions
on paper we can&apos;t include the same document in two folders.
tree structure of folders to organize documents....
secciones son titulares
se pueden anidar
entradas agrupan campos
tree structure inside documents, organize entries in sections and fields in entries
procesamiento: calculos que pueden darse a nivel de la base de datos, dentro de las consultas o como stored procedures
OLTP&gt; online transaction processing
http://datawarehouse4u.info/OLTP-vs-OLAP.html
This is just to give an idea of the options, not a strict comparison.
Entity/Actribute/Value column not included.
Mayn brands not included.
http://neo4j.com/docs/stable/tutorial-comparing-models.html
didnt added object databases, I dont know enough...
https://en.wikipedia.org/wiki/InterSystems_Cach%C3%A9
http://www.objectdb.com/
https://en.wikipedia.org/wiki/Db4o
We are not suggesting RM is better, we are trying to move forward choosing one, and come avoid that discussion.
Lots of JOINS: this is true if we are querying all the data together, of course it depends on the design and implementation of each system, but most queries will not query lots of tables together, and optimizations can be done.
The goal of this slide is to make attendees to focus just on one or two technological options, and introduce the topic of ORM.
We are NOT suggesting, or saying that one technology is better than another.
The goal of this slide is to make attendees to focus just on one or two technological options, and introduce the topic of ORM.
We are NOT suggesting, or saying that one technology is better than another.
MODEL BASED TRANSFORMATIONS vs. 1-to-1 model ad-hoc transformations.
Las transformaciones son importantes para mover datos entre distintas DBs, Sistemas, y para proveer servicios.
It is very probable we have an OO model because we use an OO programming language.
Mas adelante veremos ORM
so if we use a JSON DB we can transform it to XML and give that to the application and viceversa.
IMPORTANT: put the DvCodedText hierarchy in the whiteboard, we&apos;ll use it in the slide with the EHRServer database design.
openEHR process to define clinical records
el modelo de información tiene observation, evaluatio, instruction y action, no tiene BP, heart rate, diagnosis, medication prescription, etc.
https://raw.githubusercontent.com/ppazos/cabolabs-ehrserver/master/opts/Encuentro.opt
archetypes and templates are putting pieces together from the IM to represent a full clinical document, it&apos;s like lego...
mostrar donde esta path, archetype id, node id, etc.
FIXME: relacion COMPO-EVENT CONTEXT
If you are creating a DBMS independent solution, consider the type correspondences between different DBMS, some tools already do that, like Grails ORM.
Because of &quot;identity&quot;, one attribute will be &quot;id&quot;.
one-to-one (bidirectional) can be embeded
many-to-one (unidirectional)
many-to-one with self reference (person-person relationship)
many-to-many JOIN table
one-to-many (bidirectional) backlink (at the DB level is the same as many-to-one unidirectional)
MySQL - Query-Oriented Database, that&apos;s why we use &quot;indexes&quot;.
IMPORTANT: reference the DvCodedText hierarchy in the whiteboard (from slide 25).
SQLServer - Operational / Transactional DB
Just introducing the AQL concept.
The example represents an AQL query over the archetype openEHREHR-OBSERVATION lab _test _full _blood _count.v1 taken from the International Clinical Knowledge Manager [41] to retrieve all the tests of full blood count indicating a moderate leukocytosis. Following the openEHR RM class hierarchy, the query selects for the
EHR identified as 1ADC27 any encounter composition that contains a full blood count test observation. The condition of the where
clause constraints to values in white cell count between 11 × 10^9
and 17 × 10^9
. The TIME WINDOW section is indicating that the
fetched values should be restricted to the period of 1 year (P1Y)
before 2014-02-12 (ISO-8601)
The example represents an AQL query over the archetype openEHREHR-OBSERVATION lab _test _full _blood _count.v1 taken from the International Clinical Knowledge Manager [41] to retrieve all the tests of full blood count indicating a moderate leukocytosis. Following the openEHR RM class hierarchy, the query selects for the
EHR identified as 1ADC27 any encounter composition that contains a full blood count test observation. The condition of the where
clause constraints to values in white cell count between 11 × 10^9
and 17 × 10^9
. The TIME WINDOW section is indicating that the
fetched values should be restricted to the period of 1 year (P1Y)
before 2014-02-12 (ISO-8601)
get full clinical documents or data points
choose semantic identifiers to define criteria or projections
for criteria, define the logic operator
save and execute! test UI or from the REST API