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ORAL CANCER – A SILENT KILLER
Dr. Amol Dumbre Patil DNB
Consultant Oncosurgeon
Ruby Hall Clinic,Pune
KEM Hospital ,Pune
CANCER
CANCER
CANCER PREVENTION
 Healthy lifestyle
 Avoid tobacco: any form
 Alcohol
 Diet
 Exercise
 Mental stress
 Treatment of infections
 Screening
CANCER CURE
 Early diagnosis
 Prompt, aggressive and correct treatment
 No pain…….No gain
 Regular follow-up
FIRST CHANCE IS THE BEST CHANCE
EARLY DIAGNOSIS
 Screening
 Identify symptoms
 Seek expert help
 Good quality diagnostic tests
 Tumor markers, CT, MRI, PET Scan
 Good pathologist with good lab
 Immunohistochemistry (IHC)
SCREENING
 Finds cancer when asymptomatic
 Size very small, may not be palpable
 Cancer found is usually curable
 Simple tests
 Can be used in
 Breast cancer
 Cervical cancer
 Colon cacner
 Oral cancer
 Finds cancer early in persons who would otherwise surely get it later in
advanced, incurable stage.
SURGERY
CHEMOTHERAPYRADIOTHERAPY
TREATMENT
ORAL CANCER
 Magnitude of problem
 Prvention-primary and secondory
 Oral examination
 Premalignat lesions
 Cancerious lesions
 Treatment
INCIDENCE AND SURVIVAL
OF ORAL OR PHARYNGEAL CANCER
 30,000 new cases diagnosed yearly
 8,000 deaths each year
 5 year survival rate: 50%
USA
 New cases of cancers in India per year- about
7,00,000
 Tobacco related cancers - about 3,00,000
 Cancer of uteri - 1,00,000
 breast cancer – 80,000
(TMH-preventive oncology department)
ORAL CANCER
MORBIDITY & MORTALITY
 Most common cause of cancer death in most
parts of Asia
 5 year survival (20 -50 %)
 50,000 deaths in India annually. Primarily due to
late presentation (60-80%)
 Tata Memorial Hospital Of 2275 cases- Only 9%
in Stage I & II
BATTLE AGAINST ORAL CANCER !
 • Prevention
 • Improved treatment ( no significant change in
last 50 years)
ORAL CANCER – PREVENTION
 Primary Prevention
 Secondary Prevention – Early detection
PRIMARY PREVENTION
 Cancer prevention- Addressing the etiologic
agents
 Ban tobacco
 Behavioral modifications
 Educate the people
TOBACCO BAN – IMPLICATIONS
 India 3rd largest producer of tobacco
 900,000 employed in growing and curing
industry and 3.4 million in manufacturing 97.7
million dollar trade surplus
 Smokeless tobacco $ 1 billion annually = 0.2 %
of the gross national product
“only industry that has had a constant growth
for last few decades
SECONDARY PREVENTION
 Early detection of premalignant and malignant
lesions
Screening
EARLY DETECTION SAVES LIVES
 5-year survival for localized disease is 76%
 5-year survival for metastatic disease is 19%
EARLY DETECTION
 Increase survival
 Decreases morbidity
 Decreases cost of treatment
EARLY DETECTION IS OFTEN POSSIBLE
 Tissue changes in the mouth that may signal
cancer can often be seen and felt easily.
EXAMINATION OVERVIEW
 Head and neck exam should be a routine part of
dental and medical check-ups.
 Take a history of alcohol and tobacco use.
 Follow up on suspicious signs.
TOOLS AND TIME
 Proper lighting
 Dental mouth mirror
 Gauze squares
 Gloves
 5 minutes
EXTRAORAL EXAMINATION
PERIORAL AND INTRAORAL SOFT
TISSUE EXAMINATION: LIPS
PERIORAL AND INTRAORAL SOFT
TISSUE EXAMINATION: LABIAL MUCOSA
PERIORAL AND INTRAORAL SOFT
TISSUE EXAMINATION: LABIAL MUCOSA
PERIORAL AND INTRAORAL SOFT
TISSUE EXAMINATION: BUCCAL MUCOSA
PERIORAL AND INTRAORAL SOFT
TISSUE EXAMINATION: BUCCAL MUCOSA
PERIORAL AND INTRAORAL SOFT
TISSUE EXAMINATION: GINGIVA
PERIORAL AND INTRAORAL SOFT
TISSUE EXAMINATION: DORSUM OF
THE TONGUE
PERIORAL AND INTRAORAL SOFT
TISSUE EXAMINATION: LEFT MARGIN OF THE TONGUE
PERIORAL AND INTRAORAL SOFT
TISSUE EXAMINATION: RIGHT MARGIN OF THE TONGUE
PERIORAL AND INTRAORAL SOFT
TISSUE EXAMINATION: VENTRAL SURFACE OF THE
TONGUE
PERIORAL AND INTRAORAL SOFT
TISSUE EXAMINATION: HARD PALATE
PERIORAL AND INTRAORAL SOFT
TISSUE EXAMINATION: OROPHARYNX
PERIORAL AND INTRAORAL SOFT
TISSUE EXAMINATION
PREMALIGNAT CONDITIONS
Leukoplakia
Erythroplakia
Oral submucous fibrosis
PREMALIGNANT CONDITIONS-
LEUKOPLAKIA
ERYTHROPLAKIA
ORAL SUBMUCOUS FIBROSIS
MALIGNANT CONDITIONS
TREATMENT
 Surgery
 Radiation
 Chemotherapy
HEMIMANDIBULECTOMY
LIP WIDE EXCISION AND
RECONSTRUCTION
BUCCAL MUCOSA WIDE EXCISION
COMONDO OPERATION
 There is still much to be done. Oral cancer remains
a major health problem in India, and only dedicated,
sustained efforts towards early detection and
prevention will reduce the burden of this disease.
THANKS…
INTRODUCTION
 Oral Cancer is the sixth leading cause of cancer
worldwide
 The survival rate was 52%.
 Oral cancer generally are socially derived diseases.
 Tobacco and alcohol are synergistic effect
 Treatment of early oral cancer is surgery. Locally
advanced T3/4 are best treated with combined
surgery and Radiotherapy.
 High risk of second primary cancer. (Field
cancerization)
THE ABILITY TO CONTROL ORAL CANCER
WILL BE DEPEND ON:
PREVENTION
EARLY DIAGNOSIS
CONTINUING EDUCATIONAL CAMPAIGNS
"THERE ARE ABOUT 7,00,000 NEW CASES OF
CANCERS IN INDIA OUT OF WHICH TOBACCO
RELATED CANCERS ARE ABOUT 3,00,000, CANCER
OF UTERI ARE 1,00,000 AND 80,000 BREAST
CANCER. COST OF TREATMENT OF ORAL CANCER
IS ABOUT 3.5 LAKH. THIS CAN BE COMPLETELY
PREVENTED BY SIMPLE CHANGES IN LIFESTYLE AND
REGULAR SCREENING AND EVEN HAVE HEALTH
BENEFITS THAT REACH BEYOND CANCER. ABOUT
2000 DEATHS A DAY IN INDIA IS TOBACCO
RELATED."
Despite the fact that the oral cavity is
accessible for visual examination, and that
oral cancers and premalignant lesions
have well-defined clinical diagnostic
features, oral cancers are typically
detected in their advanced stages. In fact,
in India, 60-80% of patients present with
advanced disease as compared to 40% in
developed countries. Consistent with
patients presenting for medical care with
more advanced disease in India compared
with developed countries, overall survival is
also reduced. Early detection would not
only improve the cure rate, but it would
also lower the cost and morbidity
associated with treatment.
In this randomized, controlled trial of
almost 192,000 people, carried out over an
eight-year period, there was a significant
reduction in mortality in the intervention
arm (29.9 cases per 100,000) versus the
control arm (45.4 cases per 100,000), due
to detection of oral cancer at an early
stage.
Oral cancer  by Dr Amol Dumbre

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Oral cancer by Dr Amol Dumbre

  • 1. ORAL CANCER – A SILENT KILLER Dr. Amol Dumbre Patil DNB Consultant Oncosurgeon Ruby Hall Clinic,Pune KEM Hospital ,Pune
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  • 15. CANCER PREVENTION  Healthy lifestyle  Avoid tobacco: any form  Alcohol  Diet  Exercise  Mental stress  Treatment of infections  Screening
  • 16. CANCER CURE  Early diagnosis  Prompt, aggressive and correct treatment  No pain…….No gain  Regular follow-up
  • 17. FIRST CHANCE IS THE BEST CHANCE
  • 18. EARLY DIAGNOSIS  Screening  Identify symptoms  Seek expert help  Good quality diagnostic tests  Tumor markers, CT, MRI, PET Scan  Good pathologist with good lab  Immunohistochemistry (IHC)
  • 19. SCREENING  Finds cancer when asymptomatic  Size very small, may not be palpable  Cancer found is usually curable  Simple tests  Can be used in  Breast cancer  Cervical cancer  Colon cacner  Oral cancer  Finds cancer early in persons who would otherwise surely get it later in advanced, incurable stage.
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  • 26. ORAL CANCER  Magnitude of problem  Prvention-primary and secondory  Oral examination  Premalignat lesions  Cancerious lesions  Treatment
  • 27. INCIDENCE AND SURVIVAL OF ORAL OR PHARYNGEAL CANCER  30,000 new cases diagnosed yearly  8,000 deaths each year  5 year survival rate: 50% USA
  • 28.  New cases of cancers in India per year- about 7,00,000  Tobacco related cancers - about 3,00,000  Cancer of uteri - 1,00,000  breast cancer – 80,000 (TMH-preventive oncology department)
  • 29. ORAL CANCER MORBIDITY & MORTALITY  Most common cause of cancer death in most parts of Asia  5 year survival (20 -50 %)  50,000 deaths in India annually. Primarily due to late presentation (60-80%)  Tata Memorial Hospital Of 2275 cases- Only 9% in Stage I & II
  • 30. BATTLE AGAINST ORAL CANCER !  • Prevention  • Improved treatment ( no significant change in last 50 years)
  • 31. ORAL CANCER – PREVENTION  Primary Prevention  Secondary Prevention – Early detection
  • 32. PRIMARY PREVENTION  Cancer prevention- Addressing the etiologic agents  Ban tobacco  Behavioral modifications  Educate the people
  • 33. TOBACCO BAN – IMPLICATIONS  India 3rd largest producer of tobacco  900,000 employed in growing and curing industry and 3.4 million in manufacturing 97.7 million dollar trade surplus  Smokeless tobacco $ 1 billion annually = 0.2 % of the gross national product “only industry that has had a constant growth for last few decades
  • 34. SECONDARY PREVENTION  Early detection of premalignant and malignant lesions Screening
  • 35. EARLY DETECTION SAVES LIVES  5-year survival for localized disease is 76%  5-year survival for metastatic disease is 19%
  • 36. EARLY DETECTION  Increase survival  Decreases morbidity  Decreases cost of treatment
  • 37. EARLY DETECTION IS OFTEN POSSIBLE  Tissue changes in the mouth that may signal cancer can often be seen and felt easily.
  • 38. EXAMINATION OVERVIEW  Head and neck exam should be a routine part of dental and medical check-ups.  Take a history of alcohol and tobacco use.  Follow up on suspicious signs.
  • 39. TOOLS AND TIME  Proper lighting  Dental mouth mirror  Gauze squares  Gloves  5 minutes
  • 41. PERIORAL AND INTRAORAL SOFT TISSUE EXAMINATION: LIPS
  • 42. PERIORAL AND INTRAORAL SOFT TISSUE EXAMINATION: LABIAL MUCOSA
  • 43. PERIORAL AND INTRAORAL SOFT TISSUE EXAMINATION: LABIAL MUCOSA
  • 44. PERIORAL AND INTRAORAL SOFT TISSUE EXAMINATION: BUCCAL MUCOSA
  • 45. PERIORAL AND INTRAORAL SOFT TISSUE EXAMINATION: BUCCAL MUCOSA
  • 46. PERIORAL AND INTRAORAL SOFT TISSUE EXAMINATION: GINGIVA
  • 47. PERIORAL AND INTRAORAL SOFT TISSUE EXAMINATION: DORSUM OF THE TONGUE
  • 48. PERIORAL AND INTRAORAL SOFT TISSUE EXAMINATION: LEFT MARGIN OF THE TONGUE
  • 49. PERIORAL AND INTRAORAL SOFT TISSUE EXAMINATION: RIGHT MARGIN OF THE TONGUE
  • 50. PERIORAL AND INTRAORAL SOFT TISSUE EXAMINATION: VENTRAL SURFACE OF THE TONGUE
  • 51. PERIORAL AND INTRAORAL SOFT TISSUE EXAMINATION: HARD PALATE
  • 52. PERIORAL AND INTRAORAL SOFT TISSUE EXAMINATION: OROPHARYNX
  • 53. PERIORAL AND INTRAORAL SOFT TISSUE EXAMINATION
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  • 67. LIP WIDE EXCISION AND RECONSTRUCTION
  • 68. BUCCAL MUCOSA WIDE EXCISION
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  • 77.  There is still much to be done. Oral cancer remains a major health problem in India, and only dedicated, sustained efforts towards early detection and prevention will reduce the burden of this disease.
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  • 85. INTRODUCTION  Oral Cancer is the sixth leading cause of cancer worldwide  The survival rate was 52%.  Oral cancer generally are socially derived diseases.  Tobacco and alcohol are synergistic effect  Treatment of early oral cancer is surgery. Locally advanced T3/4 are best treated with combined surgery and Radiotherapy.  High risk of second primary cancer. (Field cancerization)
  • 86. THE ABILITY TO CONTROL ORAL CANCER WILL BE DEPEND ON: PREVENTION EARLY DIAGNOSIS CONTINUING EDUCATIONAL CAMPAIGNS
  • 87. "THERE ARE ABOUT 7,00,000 NEW CASES OF CANCERS IN INDIA OUT OF WHICH TOBACCO RELATED CANCERS ARE ABOUT 3,00,000, CANCER OF UTERI ARE 1,00,000 AND 80,000 BREAST CANCER. COST OF TREATMENT OF ORAL CANCER IS ABOUT 3.5 LAKH. THIS CAN BE COMPLETELY PREVENTED BY SIMPLE CHANGES IN LIFESTYLE AND REGULAR SCREENING AND EVEN HAVE HEALTH BENEFITS THAT REACH BEYOND CANCER. ABOUT 2000 DEATHS A DAY IN INDIA IS TOBACCO RELATED."
  • 88. Despite the fact that the oral cavity is accessible for visual examination, and that oral cancers and premalignant lesions have well-defined clinical diagnostic features, oral cancers are typically detected in their advanced stages. In fact, in India, 60-80% of patients present with advanced disease as compared to 40% in developed countries. Consistent with patients presenting for medical care with more advanced disease in India compared with developed countries, overall survival is also reduced. Early detection would not only improve the cure rate, but it would also lower the cost and morbidity associated with treatment.
  • 89. In this randomized, controlled trial of almost 192,000 people, carried out over an eight-year period, there was a significant reduction in mortality in the intervention arm (29.9 cases per 100,000) versus the control arm (45.4 cases per 100,000), due to detection of oral cancer at an early stage.