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CASE HISTORY

• S.K. , 6 yr old boy

PC
 Rash + Fever
HPC
1st day: rash started in peri-oral area 4/7 days ago;
-Itchy
-Blanching
-No apparent triggers reported by parents
-During the following 24 hours rash spread to the cheeks , UL and LL , chest , back
    and abdomen.

2nd day: associated fever and swelling on hands with rash. GP prescribed
-Calamine lotion: pruritus
- Piriton: chlorphenamine.


3rd day: symptoms' worsened, + Vomiting +Diarrhoea.
- Given paracetamol , PO and penicillin V, PO
HPC
4th day: continuing vomiting +Diarrhoea.
- The swelling in the hands extended progressively, with added
    discomfort and pain on walking and mobility of 4 limbs.

-Fever did not improve.
                                                                 TRIAGE VITALS
-He was brought in to the hospital for a second time:
                                                                 Temp: 38 C
                                                                 BP: 130/90
                                                                 RR: 28
                                                                 O2: 100%
HPC
 Any thoughts??? Any questions ??
..


No coryza symptoms

No dysuria

Immunisation up to date

No foreign travel / visitors

No family member with same symptoms
PMH
Pregnancy : normal , no drugs taken.
Perinatal: normal, no complications.
Delivery: no complications.
Postnatal: no complications.
Infancy: repetitive upper respiratory tract infections.
Development: Normal development. Walked when he was able to stand with help at 1 yr
    , able to walk at 1 , 5/12yrs
Immunizations: up to date.

Surgical Hx: Orchidopexia , due to undescended testis at 1 yr

Medical Hx: nothing reported by parents

Med: nil reg
Allergies: none known.
FH
-2 Older sisters healthy.
-No one in the family with similar symptoms.
-Father: cardiac problems and high cholesterol on father family line.
-Mother: (-)


SH
-He currently attends school on yr 1
-No problems with school, no problems socialising “he’s actually a very popular
   kid”
-No problems at home reported.
-No recent travel
-No pets
S/R
-General: looking poorly for last 4 days, feeding ok and
   drinking ok , despite vomiting.
-ENT: dry cough before the episode of rash + fever , swollen
   tonsils, difficulties with swallowing.
-GI: diarrhoea
-RS: no asthma , no SOB, no palpitations
-CVS: (-)
-GUS: urine colour changes
-NS: (-)
-MSS: pain in hand bilaterally ,
-SKIN: raised skin temperature + swelling, itchy maculopapular
   rash.
O/E
-General: alert , responsive cooperative child to examination
38 C
-RS: (-)
-CVS: (-) no cyanosis, no clubbing, no SOB, no murmurs.
-ENT: inflamed red throat, red swollen tongue, no palate
   erythema, ears: L=clear R= waspy , tonsils grade 2-3
-Eyes: no conjunctivitis
-NS: (-)
-MSS: bilateral palmar and plantar erythema, bilateral swelling
   of both UL & LL, non pitting oedema on both LL and
   UL, pulses present in both UL and LL.
-SKIN: generalised warm skin temperature +
   swelling, maculopapular rash on the back , patchy over the
   thighs.
Differentials
                       ????

- 5 viral exanthems

-Scarlet fever

-Toxin mediated rash

- Kawasaki disease
Diagnosis
Key points to reach diagnosis: fever + rash

-Decide which type of rash is:
   macular, maculopapular, vesicular purpuric.

-Determine if the child is ill.

-Beware of diagnosis Measles or Rubella without serological
   confirmation.

-If the rash is petechial or purpuric child unwell ,treat with
    penicillin IM and admit for investigation.
Investigations
                            ????
-Bloods: FBC, , CRP, ESR, U&E’s, LFT, Coag profile

-Dip stick Urine

-Throat swab

-ASO antistrepto-lysin titres

-ECG

- C3,C4
Management
- Fluids


- Antibiotics


- Antipiretic/ analgesia


- Vital signs monitoring
Scarlet Fever

- Rash that may occur with Streptoccocal pharyngitis.



- Caused by group A haemolytic streptoccoci.



- Treated with Antibiotic.
Scarlet Fever
CLINICAL FEATURES

- 2-4 incubation period


- Headache and tonsillitis appear after


- Rash develops within 2 hours


- Spreads rapidly over trunk and neck


- With increased density in the neck, axillae and groins.
Scarlet Fever
.
    CLINICAL FEATURES

    - A fine punctuate erythematous appearance


    - A “sand papery” feel.


    - And blanching on pressure.


    - Tongue white first then “red strawberry”


    - Rash lasts about 6 days followed by peeling
Scarlet Fever
.
    INVESTIGATIONS

    - Throat swab mat show group A streptococcus



    - Antistreptolysin ( ASO ) titre is high.
Scarlet Fever
.
    MANAGEMENT

    - 10- day course of penicillin V or erythromycin


    - Isolation: children should be isolated until 24th after the start of antiibiotics


    - Antibiotic prevents other children from being infected and reduce lenght of
      illness.

    - Should be started within 9 days of acute illness.


    - Follow updated hospital guidelines if at all any.
Scarlet Fever
.
    COMPLICATIONS

    Peritonsilar abscess

    Retropharyngeal abscess

    Acute Glomerulonephritis (2 weeks)

    Rheumatic fever

    Pneumonia

    Meningitis / Brain absses (incidence)

    Sepsis
Scarlet Fever
References
   Rudolf M, Lee T, Levene M. Paediatrics and Child Health. Wiley Blackwell, 2001; 3rd ed.

   Lissauer T, Clayden G. Illustrated textbook of Paediatrics. UK: Mosby Elsevier, 2007; 3rd ed.

   Tasker R, McClure R, Acerini C. Oxford handbook of Paediatrics. Oxford: Oxford University
    press, 2008.
The end

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Paediatrics - Case presentation: fever+rash

  • 1.
  • 2. CASE HISTORY • S.K. , 6 yr old boy PC  Rash + Fever
  • 3. HPC 1st day: rash started in peri-oral area 4/7 days ago; -Itchy -Blanching -No apparent triggers reported by parents -During the following 24 hours rash spread to the cheeks , UL and LL , chest , back and abdomen. 2nd day: associated fever and swelling on hands with rash. GP prescribed -Calamine lotion: pruritus - Piriton: chlorphenamine. 3rd day: symptoms' worsened, + Vomiting +Diarrhoea. - Given paracetamol , PO and penicillin V, PO
  • 4. HPC 4th day: continuing vomiting +Diarrhoea. - The swelling in the hands extended progressively, with added discomfort and pain on walking and mobility of 4 limbs. -Fever did not improve. TRIAGE VITALS -He was brought in to the hospital for a second time: Temp: 38 C BP: 130/90 RR: 28 O2: 100%
  • 5. HPC Any thoughts??? Any questions ?? .. No coryza symptoms No dysuria Immunisation up to date No foreign travel / visitors No family member with same symptoms
  • 6. PMH Pregnancy : normal , no drugs taken. Perinatal: normal, no complications. Delivery: no complications. Postnatal: no complications. Infancy: repetitive upper respiratory tract infections. Development: Normal development. Walked when he was able to stand with help at 1 yr , able to walk at 1 , 5/12yrs Immunizations: up to date. Surgical Hx: Orchidopexia , due to undescended testis at 1 yr Medical Hx: nothing reported by parents Med: nil reg Allergies: none known.
  • 7. FH -2 Older sisters healthy. -No one in the family with similar symptoms. -Father: cardiac problems and high cholesterol on father family line. -Mother: (-) SH -He currently attends school on yr 1 -No problems with school, no problems socialising “he’s actually a very popular kid” -No problems at home reported. -No recent travel -No pets
  • 8. S/R -General: looking poorly for last 4 days, feeding ok and drinking ok , despite vomiting. -ENT: dry cough before the episode of rash + fever , swollen tonsils, difficulties with swallowing. -GI: diarrhoea -RS: no asthma , no SOB, no palpitations -CVS: (-) -GUS: urine colour changes -NS: (-) -MSS: pain in hand bilaterally , -SKIN: raised skin temperature + swelling, itchy maculopapular rash.
  • 9. O/E -General: alert , responsive cooperative child to examination 38 C -RS: (-) -CVS: (-) no cyanosis, no clubbing, no SOB, no murmurs. -ENT: inflamed red throat, red swollen tongue, no palate erythema, ears: L=clear R= waspy , tonsils grade 2-3 -Eyes: no conjunctivitis -NS: (-) -MSS: bilateral palmar and plantar erythema, bilateral swelling of both UL & LL, non pitting oedema on both LL and UL, pulses present in both UL and LL. -SKIN: generalised warm skin temperature + swelling, maculopapular rash on the back , patchy over the thighs.
  • 10. Differentials ???? - 5 viral exanthems -Scarlet fever -Toxin mediated rash - Kawasaki disease
  • 11. Diagnosis Key points to reach diagnosis: fever + rash -Decide which type of rash is: macular, maculopapular, vesicular purpuric. -Determine if the child is ill. -Beware of diagnosis Measles or Rubella without serological confirmation. -If the rash is petechial or purpuric child unwell ,treat with penicillin IM and admit for investigation.
  • 12. Investigations ???? -Bloods: FBC, , CRP, ESR, U&E’s, LFT, Coag profile -Dip stick Urine -Throat swab -ASO antistrepto-lysin titres -ECG - C3,C4
  • 13. Management - Fluids - Antibiotics - Antipiretic/ analgesia - Vital signs monitoring
  • 14. Scarlet Fever - Rash that may occur with Streptoccocal pharyngitis. - Caused by group A haemolytic streptoccoci. - Treated with Antibiotic.
  • 15. Scarlet Fever CLINICAL FEATURES - 2-4 incubation period - Headache and tonsillitis appear after - Rash develops within 2 hours - Spreads rapidly over trunk and neck - With increased density in the neck, axillae and groins.
  • 16. Scarlet Fever . CLINICAL FEATURES - A fine punctuate erythematous appearance - A “sand papery” feel. - And blanching on pressure. - Tongue white first then “red strawberry” - Rash lasts about 6 days followed by peeling
  • 17. Scarlet Fever . INVESTIGATIONS - Throat swab mat show group A streptococcus - Antistreptolysin ( ASO ) titre is high.
  • 18. Scarlet Fever . MANAGEMENT - 10- day course of penicillin V or erythromycin - Isolation: children should be isolated until 24th after the start of antiibiotics - Antibiotic prevents other children from being infected and reduce lenght of illness. - Should be started within 9 days of acute illness. - Follow updated hospital guidelines if at all any.
  • 19. Scarlet Fever . COMPLICATIONS Peritonsilar abscess Retropharyngeal abscess Acute Glomerulonephritis (2 weeks) Rheumatic fever Pneumonia Meningitis / Brain absses (incidence) Sepsis
  • 21. References  Rudolf M, Lee T, Levene M. Paediatrics and Child Health. Wiley Blackwell, 2001; 3rd ed.  Lissauer T, Clayden G. Illustrated textbook of Paediatrics. UK: Mosby Elsevier, 2007; 3rd ed.  Tasker R, McClure R, Acerini C. Oxford handbook of Paediatrics. Oxford: Oxford University press, 2008.