This document discusses placenta accreta syndrome, including risk factors, diagnostic methods, and management strategies. It begins with an overview of placenta accreta classifications. Ultrasound and MRI are important diagnostic tools, with ultrasound being the primary method. Risk factors include prior c-sections, placenta previa, and uterine surgeries. Early diagnosis allows for elective c-section and interventions like arterial embolization to reduce bleeding. Hysterectomy is often needed to control hemorrhage but conservative approaches aim to preserve the uterus. Proper multidisciplinary care and prevention of delays in management can improve outcomes for this serious condition.
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PLACENTA ACCRETA SYNDROME: RISK FACTORS AND MANAGEMENT
1. PLACENTA ACCRETA
SYNDROME Risk Factors and
Management
PRESENTED BY:
DR. KIRAN PANDEY
Prof. & HOD
Dept. of Obs. & Gyne.
GSVM MEDICAL COLLEGE KANPUR
DR. PAVIKA LAL
Assistant Professor
Dept. of Obs. & Gyne.
GSVM MEDICAL COLLEGE KANPUR
2. DR. KIRAN PANDEY
Head of department, dept of OBG,
GSVM Medical College,Kanpur.
Secretary upsc AGOI 2017-2019
President 2016-2018,Kanpur obs&gynaesociety
Organizing secretary: WWWCON-2018
Organizing chairperson: Adolescent Workshop,
Emergency Obstetrics Workshop- oct 2018
Organizing chairperson: National Adolescent
Conference Youth Summit and CME 2017
Organizing Secretary,National conf Obs&Gynae 2015
Organizing chairperson,Urogynecology,NDVH,Pelvic
floor
3. PLACENTA PLACENTA ACCRETA
ACCRETA SYNDROME
of an abnormal placental
implantation and firm adherence which are
classified according to the depth of invasion in
to the uterus.
PLACENTA
ACCRETA
PLACENTA ACCRETA
SYNDROME
4. ADHERENT PLACENTA syndrome
Accreta Increta Percreta
TOTAL
PLACENTA
ACCRETA
(INVOLES ALL
LOBES)
FOCAL
PLACENTA
ACCRETA
(INVOLVES
SINGLE LOBE)
PARTIAL
PLACENTA
ACCRETA
(INVOLES
ONLY TWO
LOBES)
5. Partial or total absence of the decidua basalis and
defective development of the fibrinoid or
Nitabuch layer results in abnormally firm adherence
defect of the biological functions of the
trophoblast, leading to excessive invasion of the
myometrium
shift in placental blood supply from a spiral artery
as found in normal placentation to a supply from a
larger, deeper radial or arcuate artery
High velocity blood flow in uteroplacental
circulation in placental lacunae
Hypervascularisation pattern under
placental blood flow in color doppler
6. sharp rise over the years, which may be attributed to rising
number of cesarean deliveries
.
10. Transvaginal scans are more sensitive in
confirming placental location and diagnosing
placenta previa at 20th week of gestation than
transabdominal scans.
has been the cornerstone in
diagnosing placenta accreta due to its wide
availability and high accuracy-
14. Findings suggestive of placenta accreta are-
Hypervascularity of serosa–bladder interface.
Diffuse or focal lacuna flow vascular lakes with turbulent
flow (Peak systolic velocity over 15 cm/s).
Markedly dilated vessels over peripheral
subplacentalzone.
OBLITERATION OF CLEAR
SPACE BETWEEN PLACENTA &
UTERINE WALL
MOTH -EATEN /SWISS
CHEESE APPEARANCE
DUE TO LACUNAE
HYPERVASCULARITY
15. 3-D power doppler has been shown to be superior
In diagnosing placenta percreta from accreta.
Findings on 3-D power doppler are:
16. Numerous coherent vessels involving the whole
uterine serosa–bladder junction (basal view)
Inseparable cotyledon and intervillous circulations
18. When to recommend MRI for diagnosis of
Placenta Accreta -
equivocal USG findings of abnormal
placentation
evaluation of posterior placenta in patients with
risk factors
obese patients
complementary role in specifically delineating
the
extent of an USG-diagnosed placenta percreta
19. Imaging features of normal placentation
on MRI
Homogeneous T2-intermediate signal intensity of placenta
Subtle, thin, regularly spaced placental septi.
Normal subplacental vascularity.
Triple-layered sandwich appearance of myometrium.
Pear-shape of normal gravid uterus with smooth contour.
20. Dark intra-placental bands on
T2-weighted images.
Abnormal disorganized placental
vascularity.
Focal interruptions of the
myometrial wall or extension
through the myometrium with
occasional invasion of adjacent
structures.
Heterogencity with in placenta
.disruption of pear shaped pattern
(lower segment wider than fundus)
21.
22. G3p1+1,24years female,GA 37 weeks 3 days presented with
leaking PV.
History of preterm LSCS 3 years back and spontaneous
abortion f/b D&C 1 years back.
No ANC visit single 3rd trimester USG showing SLIUF
appropriate for GA,placenta posterior and low lying
The case was opened by obstetrician.
Delivery of the fetus f/b repeated attempts to remove placenta
but within few minutes it was realised that it is adherent
placenta as the patient started bleeding
profusely(HORRIFYING !!!)
23. Hysterectomy was done but patient went into
irreversible shock and could not be revived back
Forcible and unneccessary attempt to claw off placenta
should not be done(may provoke further torrential
hemorrhage).
Multidisciplinary approach
senior obstetrician,
pelvic surgeon,
uro-surgeon (if needed)
neonatologist,
anesthetist,
24. TRIPLE P PROCEDURE
A novel uterine sparing procedure for PAS
Steps
1. Peri-operative placental ultra sound localization
of the superior edge of the placenta
2. Pelvic devasularization – pre operative
placement of intra arterial balloon catheters
3. No attempt to remove the entire placenta
*FIGO consensus guidelines on placenta accreta spectrum disorders
25. 25 years, unbooked, G4P1+2 with h/o FTLSCS 4 year
back f/b 2 spontaneous abortions(D&C done) came in
active stage of labor at 37wks + 2 days at CHC Kanpur
Dehat.
Em LSCS was done and intraoperatively it was
found to be placenta percreta with bladder
involvement. Pt bled profusely.
Subtotal hysterectomy was done along with ligation
of blood vessels going into the bladder but all in vain
as the patient’s vitals deteriorated, pt developed DIC &
anuria with ARF in postoperative period(d/t massive
blood loss)
CLINICAL SCENARIO 2
26. HOW COULD
SHE BE
BETTER
MANAGED??
Previous LSCS – Regular antenatal check ups
USG to diagnose placenta accreta.
Elective cesarean is the choice
ICU CARE- For proper management of complications (
DIC,ARF,Transfusion reactions , ARDS, Electrolyte imbalance).
27. RCOG 2011
Elective ceaserean section in asymptomatic
women is not recommended before 38 weeks
of gestation for placenta previa or before 36-
37 weeks of gestation for suspected placenta
accreta.
ACOG 2014
Elective delivery by ceaserean section at 34-
35 weeks of gestation for suspected placenta
accreta
28. What makes hysterectomy different and difficult
?
Genitourinary tract inuries
.
Prevention
Avoid cutting placenta => trans
fundal approach
PREVENTIVE SURGICAL OR
RADIOLOGICAL
DEVASULARIZATION
Placement of balloon occlusion
catheter.
Placement of pelvic pressure
packing like laprotomy devices or
balloon tamponade.
Causes
unplanned Hysterectomy
Emergency hysterectomy in
an undiagnosed placenta
accreta
Inadvertent attempt at
removal of placenta
Delivery of baby by cutting
through the placenta.
MASSIVE
BLOOD
LOSS
(3-5 ltrs)
29. Inspection
Presence of any vascular channels
noted(should not be disturbed.
Uterine incision
CLASSICAL/TRANSFUNDAL
cesarean section to avoid cutting
through the placenta f/b delivery of
fetus f/b closure of uterine incision by
WHIP stitch
30. B/L anterior division of internal iliac artery ligation done f/b uterine
artery ligation.
cesarean hysterectomyCESAREAN HYSTERECTOMY
IS CONSIDERED AS GOLD
STANDARD TREATMENT FOR
INVASIVE ACCRETA ALTHOUGH
HIGH RATES OF SEVERE MATERNAL
MORBIDITY(40-50%)
AND MORTALITY(7%)
32. G6P1+4(none alive) GA 36 weeks with H/O
previous 1 LSCS and 3 D&C was refferred to our
hospital with the USG(3D Doppler)findings of
complete central placenta with focal placent
increta
Elective LSCS was done at 37 weeks
B/L uterine artery were ligated and gentle
removal of placenta as much as possible with
leaving the adherent part of placenta “insitu
approach” closure of uterine incision.
CLINICAL SCENARIO 3
Saving the uterus was our priority
33. Postoperatively 2 units of blood was transfused along with
methotrexate adjuvant treatment* given.
Patients managed successfully
Key points during conservative management-
Gentle attempt to remove the “non accreta” portion of placenta
, thus the volume of villous tissue left insitu
Preventive radiological and surgical devascularization
(uterine/hypogastric artery)
prevents secondary hemorrhage
placental reabsorption
Methotrexate hastens placental resolution although the risk of
neutropenia
sepsis
secondary hemorrhage=> hysterectomy
34. Conservative management should
always be
attempted in patients who agree to long
term
monitoring,strongly desired to
preserved their
fertility with adequate expertise
Insufficient evidence for the use of MRI and/or serum beta HCG for the
monitoring of conservative management of PAS.
* Use of methotrexate is not routinely recommended and therefore
should only be given judiciously.
FIGO consensus guidelines on placenta accreta spectrum disorder
Int J Gynecol Obstet 2018;140:291-298
35. One step conservative surgical
approach for PAS
Vascular diconnection of newly formed feeder
vessels and seperation of invaded Ut. Tissue
from invaded bladder tissue
Upper segment hysterotomy and delivery of
fetus
Resection of all invaded myometrium with
placenta in one piece after local vascular control
Surgical procedure for hemostasis
Myometrial reconstruction in 2 planes
Bladder repair if necessary.
*FIGO consensus guidelines on placenta accreta spectrum disorders
36. Though UAE is latest interventional technique in cases of
accreta,but its not available in many of our set-ups, therefore
uterine artery ligation may be life saving.
The role of interventional radiological procedure though looks
promising, further research and prospective larger studies
are required.
37. Pearls of wisdom
My personal experience….
In cases requiring hysterectomy I personally use double set
of clamps to rapidly secure all bleeding points and remove
the uterus as soon as possible and ligate the pedicles later.
reduces blood loss effectively
I have found that uterine artery ligation prior to attempt of
removal of placenta in cases of placenta accreta may be life
saving.
Feasible alternative to uterine artery embolization in
low
resource settings .
38. THE DEADLY D’S of Accreta
DELAYED:
Delayed referral
Delayed caesarean: i.e. emergency (not elective)
Delayed decision for hysterectomy
DEFICIENCY:
Deficiency of time availability: extensive adhesions,
no time for pre-op devascularization
Deficiency of blood and blood products
Deficiency of ICU beds
Deficiency of multi-disciplinary senior team.