Transverse image of the right upper quadrant in a patient with acute cholecystitis shows the edema and thickening of the tender gallbladder wall.
Changes of early/intermediate Crohn's disease, with thickened folds, tending to asymmetry and obliteration in places. There are small apthous ulcers, and nodules, with normal diameter bowel. There is a linear mesenteric ulcer (arrowed, lower image).
There is loss of the normal mucosal outline to the large bowel, with an irregular margin and no visible haustral markings, indicating mucosal inflammation and oedema. There is marked dilatation of the large bowel, from the caecum on the right to a loop of sigmoid seen centrally in the pelvis. The appearances and the extent thus indicate a pancolitis. The transverse colon measures more than 5.5cm across, which in the presence of colitis indicates a toxic megacolon, with the risk of imminent perforation.