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Philadelphia	
  CyberKnife	
  is	
  a	
  service	
  of	
  Delaware	
  County	
  Memorial	
  Hospital,	
  a	
  member	
  of	
  the	
  Crozer-­‐Keystone	
  Health	
  System.	
  



2010	
  West	
  Chester	
  Pike	
  Suite	
  115	
  Havertown,	
  PA	
  19083	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  (610)	
  446-­‐6850	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  www.phillycyberknife.com
What is CyberKnife?
The	
  world’s	
  only	
  roboHc	
  radiosurgery	
  system,	
  CyberKnife	
  treats	
  
paHents	
  with	
  a	
  procedure	
  called	
  stereotac(c	
  radiosurgery.	
  
StereotacHc	
  radiosurgery	
  is	
  a	
  noninvasive	
  method	
  of	
  treaHng	
  tumors	
  
with	
  high-­‐dose	
  radiaHon	
  precisely	
  aimed	
  from	
  different	
  angles.	
  	
  


How	
  does	
  CyberKnife	
  work?	
  

CyberKnife	
  does	
  not	
  require	
  surgery	
  and	
  there	
  is	
  no	
  cu7ng	
  or	
  
anesthesia	
  required.	
  Comprised	
  of	
  a	
  compact	
  linear	
  
accelerator	
  -­‐	
  a	
  machine	
  that	
  generates	
  a	
  radiaHon	
  beam	
  -­‐	
  
aRached	
  to	
  a	
  highly	
  maneuverable	
  roboHc	
  arm.	
  	
  
	
  
•  The	
  machine’s	
  roboHc	
  arm	
  moves	
  around	
  you,	
  aiming	
  and	
  
     firing	
  targeted	
  radiaHon	
  beams	
  from	
  numerous	
  angles.	
  
•  The	
  imaging	
  and	
  tracking	
  system	
  conHnually	
  updates	
  the	
  
     tumor	
  locaHon	
  throughout	
  the	
  treatment	
  procedure,	
  
     compensaHng	
  for	
  paHent	
  movements	
  like	
  breathing.	
  
•  Treatment	
  sessions	
  typically	
  last	
  30	
  -­‐	
  60	
  minutes.	
  




    2010	
  West	
  Chester	
  Pike	
  Suite	
  115	
  Havertown,	
  PA	
  19083	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  (610)	
  446-­‐6850	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  www.phillycyberknife.com
2010	
  West	
  Chester	
  Pike	
  Suite	
  115	
  Havertown,	
  PA	
  19083	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  (610)	
  446-­‐6850	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  www.phillycyberknife.com
Why Choose CyberKnife?
                                                                                     CyberKnife	
                              Conven(onal	
                            Linac	
                                   Proton	
  Therapy	
  
                                                                                     Stereotac(c	
                             Radia(on	
                               Stereotac(c	
  
                                                                                     Radiosurgery	
                            Therapy	
                                Radiosurgery	
  
                                            Daily	
  dose	
                                   5.0-­‐2.0	
  	
                           1.8-­‐3.0	
  	
                          5.0-­‐20	
  	
                            1.8-­‐2.0	
  	
  
                                                                                       Gy	
  per	
  fracHon	
                    Gy	
  per	
  fracHon	
                   Gy	
  per	
  fracHon	
                    Gy	
  per	
  fracHon	
  
                                            Number	
  of	
  
                                                                                              3-­‐5	
  days	
                         6-­‐7	
  weeks	
                           3-­‐5	
  days	
                         6-­‐7	
  weeks	
  
                                            treatments	
  
                                            Accuracy	
  ((ssue	
                                                                      20-­‐30	
                                                                          20-­‐30	
  
                                                                                       1.5	
  millimeters	
                                                               1-­‐5	
  millimeters	
  
                                            margin)	
                                                                               millimeters	
                                                                      millimeters	
  
                                            Number	
  of	
  
                                            radia(on	
  beams	
   100-­‐200+	
  beams	
                                              2-­‐7	
  beams	
                         5-­‐15	
  beams	
                         2-­‐3	
  beams	
  


                                            Con(nuous	
  
                                            correc(on	
  for	
  
                                            breathing	
  and	
                                     YES	
                                     NO	
                                     NO	
                                      NO	
  
                                            movement	
  



•      Treats	
  paHents	
  in	
  as	
  few	
  as	
  one	
  to	
  five	
  visits	
   •                                                                             Reaches	
  most	
  tumors	
  from	
  virtually	
  unlimited	
  
•      Pain	
  free	
  and	
  requires	
  no	
  anesthesia	
                                                                                                      direcHons	
  with	
  roboHc	
  mobility	
  
•      Minimal	
  side	
  effects	
                                                  •                                                                             Minimizes	
  radiaHon	
  exposure	
  to	
  healthy	
  Hssue	
  
•      OutpaHent	
  procedure	
  	
                                                                                                                               surrounding	
  a	
  tumor	
  site	
  
•      Constantly	
  corrects	
  for	
  tumor	
  or	
  paHent	
  movement	
   •                                                                                   Lesions	
  previously	
  treated	
  with	
  maximum	
  allowed	
  
       throughout	
  procedures	
                                                                                                                                 radiaHon	
  doses	
  may	
  be	
  treated	
  



     2010	
  West	
  Chester	
  Pike	
  Suite	
  115	
  Havertown,	
  PA	
  19083	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  (610)	
  446-­‐6850	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  www.phillycyberknife.com
What does CyberKnife treat?
                                                                                                                                                   •          Arteriovenous	
  malformaHon	
  
                                                                                                                                                   •          Bone	
  metastases	
  
                                                                                                                                                   •          Brain	
  tumors	
  
                                                                                                                                                                 •  AcousHc	
  neuroma	
  
                                                                                                                                                                 •  Brain	
  metastases	
  
                                                                                                                                                                 •  Gliomas	
  
                                                                                                                                                                          •  Astrocytoma	
  
                                                                                                                                                                          •  Glioblastoma	
  mulHforme	
  
                                                                                                                                                                          •  Glioma	
  
                                                                                                                                                                          •  oligodendroglioma	
  
                                                                                                                                                                 •  Meningioma	
  
                                                                                                                                                                 •  Pituitary	
  adenoma	
  
                                                                                                                                                   •          Kidney	
  tumors	
  
                                                                                                                                                   •          Liver	
  tumors	
  
                                                                                                                                                   •          Lung	
  tumors	
  
                                                                                                                                                   •          Ocular/orbital	
  tumors	
  
                                                                                                                                                   •          Prostate	
  cancer	
  
                                                                                                                                                   •          PancreaHc	
  cancer	
  
                                                                                                                                                   •          Spinal	
  tumors	
  
                                                                                                                                                   •          Trigeminal	
  neuralgia	
  



2010	
  West	
  Chester	
  Pike	
  Suite	
  115	
  Havertown,	
  PA	
  19083	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  (610)	
  446-­‐6850	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  www.phillycyberknife.com
What is the treatment process?
          ConsultaHon	
                                                             Meet	
  with	
  the	
  
                                                                                                                                                  Create	
  an	
  
                                                                                                                                                individualized	
  
          Appointment	
                                                            CyberKnife	
  team	
  
                                                                                                                                               treatment	
  plan 	
  	
  




           PotenHal	
                                                                                                                                                                                                                                              Tissue	
  Markers	
  
         Pretreatment	
                                                                   	
  CT	
  Scan	
                                              	
  MRI	
                                            Lab	
  Studies	
                                   (extracranial	
  tumors	
  
                                                                                                                                                                                                                                                                      or	
  lesions)	
  
         Procedures*	
  
                                                                                                                                                                                                      The	
  advanced	
  tracking	
  
                                                                                                                                               CyberKnife’s	
                                           system	
  takes	
  x-­‐ray	
  
             CyberKnife	
                                                          Technicians	
  help	
  
                                                                                     you	
  onto	
  the	
  
                                                                                                                                            roboHc	
  arm	
  moves	
  
                                                                                                                                             around	
  you	
  firing	
  
                                                                                                                                                                                                       images	
  to	
  ensure	
  the	
  
                                                                                                                                                                                                                                                                         If	
  needed,	
  the	
  
                                                                                                                                                                                                                                                                       paHent	
  returns	
  for	
  

             Treatment	
                                                           treatment	
  table	
                                     targeted	
  radiaHon	
  
                                                                                                                                                  beams	
  
                                                                                                                                                                                                          radiaHon	
  beam	
  
                                                                                                                                                                                                      remains	
  locked	
  on	
  the	
  
                                                                                                                                                                                                                                                                          up	
  to	
  4	
  more	
  
                                                                                                                                                                                                                                                                           treatments.	
  
                                                                                                                                                                                                                tumor	
  



                                                                                 Follow-­‐up	
  imaging	
  
                                                                                    and	
  physical	
  
               Follow-­‐up	
                                                      consultaHon	
  to	
  
                                                                                  monitor	
  tumor’s	
  
                                                                                      progress	
  




*The	
  procedures	
  required	
  as	
  part	
  of	
  your	
  individualized	
  treatment	
  plan,	
  and	
  the	
  order	
  in	
  which	
  they	
  will	
  occur,	
  will	
  be	
  explained	
  during	
  
your	
  consultaHon	
  visit.	
  



         2010	
  West	
  Chester	
  Pike	
  Suite	
  115	
  Havertown,	
  PA	
  19083	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  (610)	
  446-­‐6850	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  www.phillycyberknife.com
Our Center
Philadelphia	
  CyberKnife	
  established	
  the	
  first	
  CyberKnife	
  program	
  in	
  the	
  greater	
  Philadelphia	
  area.	
  One	
  of	
  the	
  
most	
  prolific	
  invesHgators	
  in	
  the	
  history	
  of	
  radiaHon	
  oncology,	
  Medical	
  Director	
  Dr.	
  Luther	
  Brady	
  has	
  over	
  600	
  
publicaHons	
  to	
  his	
  credit,	
  including	
  papers	
  on	
  tumors	
  of	
  the	
  eye	
  and	
  orbit,	
  a	
  subject	
  on	
  which	
  he	
  is	
  considered	
  a	
  
world	
  authority,	
  to	
  the	
  more	
  common	
  cancers	
  of	
  the	
  lung.	
  He	
  has	
  received	
  countless	
  honors,	
  medals	
  and	
  awards	
  
throughout	
  his	
  disHnguished	
  career.	
  In	
  addiHon,	
  several	
  members	
  of	
  the	
  center’s	
  team	
  of	
  prolific	
  researchers	
  
regularly	
  present	
  clinical	
  research	
  findings	
  at	
  internaHonal	
  oncology	
  conferences.	
  Our	
  paHents	
  come	
  from	
  
throughout	
  the	
  eastern	
  United	
  States,	
  as	
  well	
  as	
  numerous	
  countries	
  around	
  the	
  world,	
  including	
  England,	
  India	
  
and	
  Malaysia.	
  	
  
	
  
                                                                                                                                                                      Medical	
  Director:	
  Dr.	
  Luther	
  Brady	
  
                                                                                                                                                                      	
  
                                                                                                                                                                      Associate	
  Medical	
  Director:	
  Dr.	
  John	
  Lamond	
  
                                                                                                                                                                      	
  
                                                                                                                                                                      CyberKnife	
  Nurse:	
  Michael	
  Good	
  
                                                                                                                                                                      	
  
                                                                                                                                                                      	
  
                                                                                                                                                                      Connect	
  with	
  us	
  
                                                                                                                                                                      	
  




   2010	
  West	
  Chester	
  Pike	
  Suite	
  115	
  Havertown,	
  PA	
  19083	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  (610)	
  446-­‐6850	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  www.phillycyberknife.com
The US Radiosurgery Network



In	
  partnership	
  with	
  Delaware	
  County	
  Memorial	
  Hospital,	
  Philadelphia	
  CyberKnife	
  is	
  a	
  US	
  Radiosurgery	
  facility.	
  
	
  
Based	
  in	
  Nashville,	
  Tennessee,	
  US	
  Radiosurgery	
  is	
  a	
  division	
  of	
  Alliance	
  Oncology	
  and	
  partners	
  with	
  hospitals	
  
and	
  physician	
  groups	
  around	
  the	
  U.S.	
  to	
  develop	
  and	
  operate	
  full-­‐body	
  radiosurgical	
  centers.	
  	
  
	
  
Collec(vely,	
  the	
  US	
  Radiosurgery	
  network	
  of	
  centers	
  has	
  treated	
  thousands	
  of	
  pa(ents	
  since	
  the	
  opening	
  of	
  
the	
  company’s	
  first	
  center	
  in	
  2003.	
  The	
  group	
  of	
  faciliHes	
  is	
  acHvely	
  engaged	
  in	
  research,	
  with	
  physicians	
  
regularly	
  presenHng	
  papers	
  and	
  authoring	
  arHcles	
  related	
  to	
  the	
  efficacy	
  of	
  CyberKnife	
  treatment	
  for	
  various	
  
types	
  of	
  tumors	
  and	
  lesions.	
  Tumors	
  of	
  the	
  lung,	
  brain	
  and	
  prostate,	
  as	
  well	
  as	
  certain	
  funcHonal	
  disorders	
  such	
  
as	
  trigeminal	
  neuralgia,	
  have	
  become	
  key	
  treatment	
  areas	
  throughout	
  the	
  network	
  of	
  centers.	
  
	
  




 2010	
  West	
  Chester	
  Pike	
  Suite	
  115	
  Havertown,	
  PA	
  19083	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  (610)	
  446-­‐6850	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  www.phillycyberknife.com

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Philadelphia CyberKnife

  • 1. Philadelphia  CyberKnife  is  a  service  of  Delaware  County  Memorial  Hospital,  a  member  of  the  Crozer-­‐Keystone  Health  System.   2010  West  Chester  Pike  Suite  115  Havertown,  PA  19083                                                (610)  446-­‐6850                                  www.phillycyberknife.com
  • 2. What is CyberKnife? The  world’s  only  roboHc  radiosurgery  system,  CyberKnife  treats   paHents  with  a  procedure  called  stereotac(c  radiosurgery.   StereotacHc  radiosurgery  is  a  noninvasive  method  of  treaHng  tumors   with  high-­‐dose  radiaHon  precisely  aimed  from  different  angles.     How  does  CyberKnife  work?   CyberKnife  does  not  require  surgery  and  there  is  no  cu7ng  or   anesthesia  required.  Comprised  of  a  compact  linear   accelerator  -­‐  a  machine  that  generates  a  radiaHon  beam  -­‐   aRached  to  a  highly  maneuverable  roboHc  arm.       •  The  machine’s  roboHc  arm  moves  around  you,  aiming  and   firing  targeted  radiaHon  beams  from  numerous  angles.   •  The  imaging  and  tracking  system  conHnually  updates  the   tumor  locaHon  throughout  the  treatment  procedure,   compensaHng  for  paHent  movements  like  breathing.   •  Treatment  sessions  typically  last  30  -­‐  60  minutes.   2010  West  Chester  Pike  Suite  115  Havertown,  PA  19083                                                (610)  446-­‐6850                                  www.phillycyberknife.com
  • 3. 2010  West  Chester  Pike  Suite  115  Havertown,  PA  19083                                                (610)  446-­‐6850                                  www.phillycyberknife.com
  • 4. Why Choose CyberKnife? CyberKnife   Conven(onal   Linac   Proton  Therapy   Stereotac(c   Radia(on   Stereotac(c   Radiosurgery   Therapy   Radiosurgery   Daily  dose   5.0-­‐2.0     1.8-­‐3.0     5.0-­‐20     1.8-­‐2.0     Gy  per  fracHon   Gy  per  fracHon   Gy  per  fracHon   Gy  per  fracHon   Number  of   3-­‐5  days   6-­‐7  weeks   3-­‐5  days   6-­‐7  weeks   treatments   Accuracy  ((ssue   20-­‐30   20-­‐30   1.5  millimeters   1-­‐5  millimeters   margin)   millimeters   millimeters   Number  of   radia(on  beams   100-­‐200+  beams   2-­‐7  beams   5-­‐15  beams   2-­‐3  beams   Con(nuous   correc(on  for   breathing  and   YES   NO   NO   NO   movement   •  Treats  paHents  in  as  few  as  one  to  five  visits   •  Reaches  most  tumors  from  virtually  unlimited   •  Pain  free  and  requires  no  anesthesia   direcHons  with  roboHc  mobility   •  Minimal  side  effects   •  Minimizes  radiaHon  exposure  to  healthy  Hssue   •  OutpaHent  procedure     surrounding  a  tumor  site   •  Constantly  corrects  for  tumor  or  paHent  movement   •  Lesions  previously  treated  with  maximum  allowed   throughout  procedures   radiaHon  doses  may  be  treated   2010  West  Chester  Pike  Suite  115  Havertown,  PA  19083                                                (610)  446-­‐6850                                  www.phillycyberknife.com
  • 5. What does CyberKnife treat? •  Arteriovenous  malformaHon   •  Bone  metastases   •  Brain  tumors   •  AcousHc  neuroma   •  Brain  metastases   •  Gliomas   •  Astrocytoma   •  Glioblastoma  mulHforme   •  Glioma   •  oligodendroglioma   •  Meningioma   •  Pituitary  adenoma   •  Kidney  tumors   •  Liver  tumors   •  Lung  tumors   •  Ocular/orbital  tumors   •  Prostate  cancer   •  PancreaHc  cancer   •  Spinal  tumors   •  Trigeminal  neuralgia   2010  West  Chester  Pike  Suite  115  Havertown,  PA  19083                                                (610)  446-­‐6850                                  www.phillycyberknife.com
  • 6. What is the treatment process? ConsultaHon   Meet  with  the   Create  an   individualized   Appointment   CyberKnife  team   treatment  plan     PotenHal   Tissue  Markers   Pretreatment    CT  Scan    MRI   Lab  Studies   (extracranial  tumors   or  lesions)   Procedures*   The  advanced  tracking   CyberKnife’s   system  takes  x-­‐ray   CyberKnife   Technicians  help   you  onto  the   roboHc  arm  moves   around  you  firing   images  to  ensure  the   If  needed,  the   paHent  returns  for   Treatment   treatment  table   targeted  radiaHon   beams   radiaHon  beam   remains  locked  on  the   up  to  4  more   treatments.   tumor   Follow-­‐up  imaging   and  physical   Follow-­‐up   consultaHon  to   monitor  tumor’s   progress   *The  procedures  required  as  part  of  your  individualized  treatment  plan,  and  the  order  in  which  they  will  occur,  will  be  explained  during   your  consultaHon  visit.   2010  West  Chester  Pike  Suite  115  Havertown,  PA  19083                                                (610)  446-­‐6850                                  www.phillycyberknife.com
  • 7. Our Center Philadelphia  CyberKnife  established  the  first  CyberKnife  program  in  the  greater  Philadelphia  area.  One  of  the   most  prolific  invesHgators  in  the  history  of  radiaHon  oncology,  Medical  Director  Dr.  Luther  Brady  has  over  600   publicaHons  to  his  credit,  including  papers  on  tumors  of  the  eye  and  orbit,  a  subject  on  which  he  is  considered  a   world  authority,  to  the  more  common  cancers  of  the  lung.  He  has  received  countless  honors,  medals  and  awards   throughout  his  disHnguished  career.  In  addiHon,  several  members  of  the  center’s  team  of  prolific  researchers   regularly  present  clinical  research  findings  at  internaHonal  oncology  conferences.  Our  paHents  come  from   throughout  the  eastern  United  States,  as  well  as  numerous  countries  around  the  world,  including  England,  India   and  Malaysia.       Medical  Director:  Dr.  Luther  Brady     Associate  Medical  Director:  Dr.  John  Lamond     CyberKnife  Nurse:  Michael  Good       Connect  with  us     2010  West  Chester  Pike  Suite  115  Havertown,  PA  19083                                                (610)  446-­‐6850                                  www.phillycyberknife.com
  • 8. The US Radiosurgery Network In  partnership  with  Delaware  County  Memorial  Hospital,  Philadelphia  CyberKnife  is  a  US  Radiosurgery  facility.     Based  in  Nashville,  Tennessee,  US  Radiosurgery  is  a  division  of  Alliance  Oncology  and  partners  with  hospitals   and  physician  groups  around  the  U.S.  to  develop  and  operate  full-­‐body  radiosurgical  centers.       Collec(vely,  the  US  Radiosurgery  network  of  centers  has  treated  thousands  of  pa(ents  since  the  opening  of   the  company’s  first  center  in  2003.  The  group  of  faciliHes  is  acHvely  engaged  in  research,  with  physicians   regularly  presenHng  papers  and  authoring  arHcles  related  to  the  efficacy  of  CyberKnife  treatment  for  various   types  of  tumors  and  lesions.  Tumors  of  the  lung,  brain  and  prostate,  as  well  as  certain  funcHonal  disorders  such   as  trigeminal  neuralgia,  have  become  key  treatment  areas  throughout  the  network  of  centers.     2010  West  Chester  Pike  Suite  115  Havertown,  PA  19083                                                (610)  446-­‐6850                                  www.phillycyberknife.com