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Development of drugs in  public-private partnership (PPP) environments Marija Mavar Haramija / Nathaniel Stanley / Pascal Maugeri April 2011   MSc Bioinfo - Computer Assisted Drug Discovery
Agenda 15-min slides + 10-min debate ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Introduction ,[object Object],[object Object],[object Object],[object Object],[object Object]
The Old Method A long and costly process ,[object Object],[object Object],[object Object],[object Object],[object Object]
The Old Method A long and costly process
The Old Method A long and costly process ,[object Object],[object Object],[object Object],[object Object]
Orphan Diseases Definition and some facts ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Orphan Diseases The Challenges ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Orphan Diseases Some examples ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Public-Private Partnerships a complementary collaboration ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Public-Private Partnerships Structure ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Public-Private Partnerships Advantages ,[object Object],[object Object],[object Object],[object Object],[object Object]
Public-Private Partnerships Disadvantages ,[object Object],[object Object],[object Object]
Public-Private Partnerships Issues ,[object Object],[object Object],[object Object],[object Object],[object Object]
Example of PPP  Bayer's initiative: Grants4Targets ,[object Object],[object Object],[object Object],[object Object],[object Object]
Example of PPP  Bayer's initiative: Grants4Targets ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Snapshot of Grants4Targets project  after 3 rounds By percentage, in what fields grants have been requested
Debate ,[object Object],[object Object],[object Object]
References some additional reading  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
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New Drugs market entry by disorder and primary indication Source:  Christopher P. Adams and Van V. Brantner. Estimating The Cost Of New Drug Development: Is It Really $802 Million? Health Affairs, 25, no.2 (2006):420-428
The example of Malaria WHO Malaria Report 2008 Estimated incidence of malaria per 1000 population, 2006
Grants 4 Targets Distribution of applications received National distribution of applications received, (RoW, Rest of the World)

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Development of drugs in public-private partnership (PPP) environments

  • 1. Development of drugs in  public-private partnership (PPP) environments Marija Mavar Haramija / Nathaniel Stanley / Pascal Maugeri April 2011   MSc Bioinfo - Computer Assisted Drug Discovery
  • 2.
  • 3.
  • 4.
  • 5. The Old Method A long and costly process
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18.
  • 19.
  • 20. New Drugs market entry by disorder and primary indication Source:  Christopher P. Adams and Van V. Brantner. Estimating The Cost Of New Drug Development: Is It Really $802 Million? Health Affairs, 25, no.2 (2006):420-428
  • 21. The example of Malaria WHO Malaria Report 2008 Estimated incidence of malaria per 1000 population, 2006
  • 22. Grants 4 Targets Distribution of applications received National distribution of applications received, (RoW, Rest of the World)

Notes de l'éditeur

  1. PARASITE
  2. PM= performance management
  3. TDR - 2 main goals: Research and development into new and improved approaches on diseases of poverty. Empowering and building research capacity in the countries where the diseases are prevalent.    TDR - 1975 MMV - 1999 GATB - 2000 DNDi - 2003 IOWH - 2001 all are working on several (10) projects, developing new drugs that will be affordable and accessible