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Cricoid Pressure
John Hinds
Conflict of interest
Conflict of interest
My nefarious plan
• Get invited to International conference in
sunny climate
• Captive audience
• Sell you this fabulous new product!
Cricolol
Appraising drugs and therapies
• Steroids in Spinal Cord injury
• Activated Protein C
• Starch solutions
• Therapeutic hypothermia in OOHCA
Cricolol: Early development
• Herbal remedy by Seamus O’Monroe in
1774
Cricolol: Early development
• Rebranded by Seamus O’Sellick in 1961
– 26 patients
– Single hospital observational study
– Non-randomised
– Non-standardised
– Dose was guessed
Administration
• Dedicated assistant during RSI
• 10mg before induction
• 30mg during induction
Administration
• Dedicated assistant during RSI
• 10mg before induction
• 30mg during induction
• Exact dose in syringe is unknown
How much is in the ampoule?
105 trained perioperative nurses
• 5% correct dose
• No correlation between knowledge of
correct dose and actual dose given
(Seamus O’Kozial et al, AORN J 2000)
A half century of Evidence
No randomised controlled trials showing
benefit.
B.S.E.’s
• Quite good at making it difficult to pass
nasogastric tubes
• Quite good for nice pictures in healthy
volunteers having MRI scans
• Some nonsense with Dye
• Seems OK in dead bodies
Any problems?
Makes Airway management
more difficult
• Airway compression in 81%
(O’Smith et al, Anaesthesiology. 2003)
• Airway obstruction in 56%
(O’Hartsilver, Anaesthesia, 2000)
Reduces success with the tube
• Worsens laryngeal view in 29%
(O’Levitan et al, Anal Emerg Med 2006)
• Makes intubation process more difficult
(O’Allman KG. J Clin Anesth 1995)
Increases vomiting and
regurgitation
• Lowers oesophageal sphincter tone and
increases regurgitation
O’Garrad et al, Anaesthesia 2004
O’Chassard et al, Can J Anaesth 1996
Narrow therapeutic window
• Dose of 30mg recommended
– No idea what’s in the ampoule
• You might break the airway
(O’ Heath et al, Br J Anaesth 1996)
• Oesophagus might explode if dose
exceeds 44mg
(O’ Ralph, O’ Wareham, Anaesthesia 1991)
Cricolol
• Evidence in well powered clinical trials
– None.
– Some BSE data
• Evidence of side effects includes:
– Airway collapse in most patients
– Complete airway obstruction in half of patients
– Increased difficulty of intubation
– Physical harm
Cricoid Pressure
3 pet hates of mine
“I use Cricoid Pressure…
I can just take it off if the
airway is difficult”
Sellick
• Cricoid on for induction…
… off at laryngoscopy
• Resulted in the highest reported incidence
of gastric regurgitation, ever.
Beware the “Trained assistant”
“Can I PLEASE have Cricoid?!”
“Can I PLEASE have Cricoid?!”
“Well if you tell me what
cupboard it’s in I’ll get it”
“I don’t believe in Cricoid
Pressure…
but I’m afraid to not use it
because of Guidelines”
Difficult Airway Society
Difficult Airway Society
• “Written guidelines should exist in each
department to cover a number of common
or serious airway problems”
• “An individual practitioner can make a
judgement about which
equipment/technique to use, and is quite
entitled to use any”
“I have to follow the Guidelines”
“Befehl ist Befehl”
Godwin’s
Law
“As an online discussion grows longer,
the probability of a comparison involving
Nazis or Hitler approaches 1”
Vote for Cricoid Pressure
Vote for Cricoid Pressure
• An Idiot.
Vote for Cricoid Pressure
• An Idiot.
• A Nazi.
Cricolol !
30mg
Suppository!
“For all the good
it does, you might
as well just stick
it up your Arse”

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Cricolol by John Hinds at smaccGOLD