1. DNA Replication Model
By: Jacob Weaver
Date: 2/6/14

2. 3
A
T
5
Key:
Adenine
G
Guanine
T
G
C
G
C
A
5
Sugar
T
T
G
A
Cytosine
C
A
A
Thymine
C
T
3
Phosphate
Helicase
This is a DNA Double Helix model.
The A-Adenine, T-Thymine, GGuanine, and C-Cytosine are the
four nitrogenous bases in each
strand of DNA. With a phosphate
and a sugar makes a nucleotide.
There is also a Helicase which
unzips the DNA. There are 9
Adenine, Thymine, Cytosine, and
Guanine bases and 9 Phosphates
and sugars

3. A
T
G
C
A
T
G
As the Helicase goes up
through the stand of DNA is
unzipping the strand. As it
unzips the strand it is
breaking the hydrogen
bonds apart from each of
the bases.
C
A
T
Key:
Adenine
Guanine
G
A
G
A
Thymine
Cytosine
C
T
C
Sugar
Phosphate
T
Helicase

4. A
T
G
C
A
T
G
This is showing how
the hydrogen bonds
are breaking as the
Helicase is moving up
through the DNA
strand.
C
A
T
G
C
A
T
G
C
A
T

5. A
T
G
Key:
Adenine
C
Thymine
Cytosine
A
Guanine
G
A
T
C
Sugar
T
Helicase
G
C
A
T
G
C
A
Phosphate
T

6. A
T
G
Key:
G
G
T
C
Cytosine
Sugar
T
C
A
T
G
C
A
Thymine
Guanine
C
A
A
Adenine
T
Phosphate
Helicase

7. Key:
A
T
A
Thymine
Guanine
G
Adenine
Cytosine
C
T
Sugar
G
Phosphate
C
Helicase
A
T
G
C
A
T
G
C
A
T

8. A
G
T
Key:
C
A
T
G
Adenine
Thymine
Guanine
Cytosine
C
Sugar
A
T
G
C
A
T
G
C
Phosphate
A
T
Helicase

9. A
T
G
The Helicase
finishing the
dividing of the
DNA strand.
C
A
T
G
C
A
T
G
C
A
T
G
C
A
T

10. T
A
G
A
Then all the single strands,
the Okarzki fragments and
Ligase will form a
phosphodiester bond.
Key:
Adenine
T
Thymine
Guanine
C
Cytosine
C
G
T
A
Sugar
Phosphate
C
G
A
T
G
C
A
T
Helicase
A
T
G
C
A
T

11. A
On the left is the leading
strand, which the bases are
synthesized continuously. On
the right is the lagging strand,
where the bases are
synthesized discontinuously .
Which DNA polymer III adds
five phosphate end of a free
floating nucleotide to expose
3’ OH.
G
A
G
T
C
T
C
A
T
A
T
G
C
G
C
A
T
A
T
G
C
G
C
A
T
A
T

12. A
T
G
C
A
G
T
C
G
C
A
T
A
T
G
C
G
C
A
T
A
T
G
C
G
C
A
T
A
T
Which DNA
polymer III adds
five phosphate
end of a free
floating nucleotide
to expose 3’ OH.
This also occurs
with the
replication fork as
well.

13. A
T
G
C
A
T
G
C
A
T
A
T
G
C
T
A
Okazaki
Fragments
G
C
G
C
A
T
A
T
G
C
G
C
A
T
A
T

14. A
T
G
A
C
T
G
C
A
T
G
C
A
T
A
T
G
C
G
C
A
T
A
T
G
C
G
C
A
T
A
T
C
G
A
T
The lagging
and leading
have now
completed the
replication
process.

15. A
T
G
C
A
The DNA
replication
continues like this
until there is
enough DNA
made.
T
G
C
A
T
G
C
A
T
A
T
G
C
G
C
A
T
A
T
G
C
G
C
A
T
A
T
C
G
A
T

16. The End of DNA Replication