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THEORIES OF AGING
by
Dr M. Rajani Cartor PT
Principal
VAPMS College of Physiotherapy
--- phenomenon of aging as it occurs over the lifespan
 aging is viewed as a total process that begins at
conception
 senescence: a change in the behavior of an organism
with age leading to a decreased power of survival and
adjustment
Theories of Aging
 Biologic
 Sociologic
 Psychologic
 Moral/Spiritual
Theories of Aging: Types
 Concerned with answering basic questions regarding the
physiological processes that occur in all living organisms as they
chronologically age
 Explanations of:
 1) deleterious effects leading to decreasing function of the
organism
 2) gradually occurring age-related changes that are progressive
over time
 3) intrinsic changes that can affect all member of a species because
of chronologic age
Biologic Theories:
 Stochastic: Explain aging as events that occur
randomly and accumulate over time
 Nonstochastic: View aging as certain predetermined,
timed phenomena
Biologic Theories: Divisions
 Error Theory
 Free Radical Theory
 Cross-Linkage Theory
 Wear & Tear Theory
Stochastic Theories
(stochastic=
having a random probability distribution or pattern that may be analysed
statisticallybut may not be predicted precisely.)
 Basis:
1)errors can occur in the transcription in any step of the protein
synthesis of DNA
2) error causes the reproduction of an enzyme or protein that is
not an exact copy
3) As transcription errors to occur, the end product would not
even resemble the original cell, thereby compromising its
functional ability
Error Theory
Originally proposed in 1963
 Free radicals are byproducts of metabolism--can increase as a
result of environmental pollutants
 When they accumulate, they damage cell membrane,
decreasing its efficiency
 The body produces antioxidants that scavenge the free
radicals
 Free radicals are also implicated in the development of plaques
associated with Alzheimer’s
Free Radical Theory
 Some proteins in the body become cross-linked, thereby not
allowing for normal metabolic activities
 Waste products accumulate
 Result: tissues do not function at optimal efficiency
 Some research supports a combination of exercise and dietary
restrictions in helping to inhibit the cross-linkage process
Cross-Linkage Theory
 Proposed first in 1882
 Cells simply wear out over time because of continued
use--rather like a machine
 Would seem to be refuted by the fact that exercise in
OA’s actually makes them MORE functional, not less
Wear & Tear Theory
Nonstochastic Theories:
Programmed Theory
Immunity Theory
 Based on lab experiments on fetal fibroblastic cells
and their reproductive capabilities in 1961
 Cells can only reproduce themselves a limited number
of times.
 Life expectancies are seen as preprogrammed within
a species-specific range
Programmed (Hayflick Limit) Theory
 Immunosenescence:Age-related functional diminution
of the immune system
 Lower rate of T-lymphocyte (“killer cells”)
proliferation in response to a stimulus
 & therefore a decrease in the body’s defense against
foreign pathogens
Immunity Theory
 Change include a decrease in humoral immune
response, often predisposing older adults to:
 1)decreased resistance to a tumor cell challenge and the
development of cancer
 2) decreased ability to initiate the immune process and
mobilize defenses in aggressively attaching pathogens
 3) increased susceptibility to auto-immune diseases
Immunity, cont’d
 Neuroendocrine Control (Pacemaker) Theory
 Metabolic Theory/Caloric Restriction
 DNA-Related Research
EMERGING THEORIES OF AGING
 “…examines the interrelated role of the neurologic
and endocrine systems over the life-span of an
individual”.
 there is a decline, or even cessation, in many of the
components of the neuroendocrine system over the
lifespan
Neuroendocrine Control
 “…proposes that all organisms have a finite amount
of metabolic lifetime and that organisms with a
higher metabolic rate have a shorter lifespan”.
 Rodent-based research has demonstrated that caloric
restriction increases the lifespan and delays the onset
of age-dependent diseases
Metobolic Theory of Aging (Caloric
Restriction)
 Major Developments:
 Mapping the human genome (“…there may be as many
as 200 genes responsible for contolling aging in
humans”)
 Discovery of telomeres
DNA-Related Research
SOCIOLOGIC THEORIES OF AGING
Disengagement Theory
Activity/Developmental Task
Theory
Continuity Theory
Age Stratification Theory
Person-Environment Fit Theory
 Changing FOCUS of Sociological considerations of
aging:
 60’s focus on losses and adaptation to them
 70’s broader global, societal, and structural factors
influencing lives of OA’s
 80’s-90’s exploration of interrelationships between OA’s
and their physical, political, environmental &
socioeconomic mileau
 Cumming & Henry--1961
 Aging seen as a developmental task in and of itself,
with its own norms & appropriate patterns of
behavior
 “appropriate” behavior patterns involved a mutual
agreement between Old Aged and society on a
reciprocal withdrawal.
 No longer supported
Disengagement Theory
 Havighurst, Neugarten, Tobin ~1963
 “Activity is viewed by this theory as necessary to maintain a
person’s life satisfaction and a positive self-concept”.
 Theory based on assumptions:
 1) it’s better to be active than inactive
 2) it is better to be happy than unhappy
 3) an older individual is the best judge of his or her own success in
achieving the first two assumptions
Activity Theory (Developmental Task
Theory)
 How a person has been throughout life is how that
person will continue through the remainder of life
 Old age is not a separate phase of life, but rather a
continuation and thus an integral component
Continuity Theory
 Riley--1985
 Society consists of groups of cohorts that age
collectively
 The people & Roles in these cohorts change &
influence each other, as does society at large
 Thus, there is a high degree of interdependence
between older adults & society
Age Stratification Theory
 Lawton, 1982
 Individuals have personal competencies that assist in dealing with
the environment:
 ego strength
 level of motor skills
 individual biologic health
 cognitive & sensory-perceptual capacities
 As a person ages, there may be changes in competencies & these
changes alter the ability to interrelate with the environment
 Significant implications in a society that is characterized by
constantly changing technology
Person-Environment Fit Theory
 Maslow’s Hierarchy of Human Needs
 Jung’s Theory of Individualism
 Erikson’s Eight Stages of Life
 Peck’s Expansion of Erikson’s Theory
 Selective Optimization with Compensation
PSYCHOLOGIC THEORIES OF AGING
 “…each individual has an innate internal hierarchy of needs that
motivates all human behaviors”.
 depicted as a pyramid; the ideal is to achieve self-actualization,
having met all the “lower” level needs successful
 “Maslow’s fully developed, self-actualized person displays high
levels of all of the following characteristics: perception of reality;
acceptance of self, others, and nature; spontaneity; problem-
solving ability; self-direction; detachment and the desire for
primacy; freshness of peak experiences; identification with other
human beings;…….
 …satisfying and changing relationships with other people; a
democratic character structure; creativity; and a sense of values.
 Only about 1% of us are truly ideal self-actualized persons
Maslow’s Hierarchy of Human Needs (1954)
 Carl Jung--1960
 origins are Freudian
 Self-realization is the goal of personality development
 as individual ages, each is capable of transforming
into a more spiritual being
Jung’s Theory of Individualism
Stages throughout the life course. Each represents a crisis to be
resolved.
 For OA’s:
 40 to 65 (middle adulthood): generativity versus self-absorption
or stagnation
 65 to death (older adulthood): ego integrity versus despair
 Self-absorbed adults will be preoccupied with their personal well-
being and material gains. Preoccupation with self leads to
stagnation of life”
 “Unsuccessful resolution of the last crisis may result in a sense of
despair in which individuals view life as a series of misfortunes,
disappointments, and failures”.
Erikson’s Eight Stages of Life(1993)
 Erikson’s last two stages are expanded to 7
 The final three of the developmental tasks for old
age:
 ego differentiation versus work role preoccupation
 body transcendence versus body preoccupation
 ego transcendence versus ego preoccupation
Peck’s Expansion of Erikson’s Theory
 Individuals develop strategies to manage losses of function that
occur over time
 3 Interacting Elements:
selection: increasing restriction ofone’s life to fewer
domains of functioning
optimization: people engage in behaviors to enrich their lives
compensation: developing suitable, alternative adaptations
Selective Optimization with
Compensation -Baltes-1987
THE END!

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Aging Theories - Rehabilitation

  • 1. THEORIES OF AGING by Dr M. Rajani Cartor PT Principal VAPMS College of Physiotherapy
  • 2. --- phenomenon of aging as it occurs over the lifespan  aging is viewed as a total process that begins at conception  senescence: a change in the behavior of an organism with age leading to a decreased power of survival and adjustment Theories of Aging
  • 3.  Biologic  Sociologic  Psychologic  Moral/Spiritual Theories of Aging: Types
  • 4.
  • 5.  Concerned with answering basic questions regarding the physiological processes that occur in all living organisms as they chronologically age  Explanations of:  1) deleterious effects leading to decreasing function of the organism  2) gradually occurring age-related changes that are progressive over time  3) intrinsic changes that can affect all member of a species because of chronologic age Biologic Theories:
  • 6.  Stochastic: Explain aging as events that occur randomly and accumulate over time  Nonstochastic: View aging as certain predetermined, timed phenomena Biologic Theories: Divisions
  • 7.
  • 8.  Error Theory  Free Radical Theory  Cross-Linkage Theory  Wear & Tear Theory Stochastic Theories (stochastic= having a random probability distribution or pattern that may be analysed statisticallybut may not be predicted precisely.)
  • 9.  Basis: 1)errors can occur in the transcription in any step of the protein synthesis of DNA 2) error causes the reproduction of an enzyme or protein that is not an exact copy 3) As transcription errors to occur, the end product would not even resemble the original cell, thereby compromising its functional ability Error Theory Originally proposed in 1963
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  • 11.
  • 12.  Free radicals are byproducts of metabolism--can increase as a result of environmental pollutants  When they accumulate, they damage cell membrane, decreasing its efficiency  The body produces antioxidants that scavenge the free radicals  Free radicals are also implicated in the development of plaques associated with Alzheimer’s Free Radical Theory
  • 13.
  • 14.  Some proteins in the body become cross-linked, thereby not allowing for normal metabolic activities  Waste products accumulate  Result: tissues do not function at optimal efficiency  Some research supports a combination of exercise and dietary restrictions in helping to inhibit the cross-linkage process Cross-Linkage Theory
  • 15.
  • 16.  Proposed first in 1882  Cells simply wear out over time because of continued use--rather like a machine  Would seem to be refuted by the fact that exercise in OA’s actually makes them MORE functional, not less Wear & Tear Theory
  • 17.
  • 19.  Based on lab experiments on fetal fibroblastic cells and their reproductive capabilities in 1961  Cells can only reproduce themselves a limited number of times.  Life expectancies are seen as preprogrammed within a species-specific range Programmed (Hayflick Limit) Theory
  • 20.  Immunosenescence:Age-related functional diminution of the immune system  Lower rate of T-lymphocyte (“killer cells”) proliferation in response to a stimulus  & therefore a decrease in the body’s defense against foreign pathogens Immunity Theory
  • 21.  Change include a decrease in humoral immune response, often predisposing older adults to:  1)decreased resistance to a tumor cell challenge and the development of cancer  2) decreased ability to initiate the immune process and mobilize defenses in aggressively attaching pathogens  3) increased susceptibility to auto-immune diseases Immunity, cont’d
  • 22.
  • 23.  Neuroendocrine Control (Pacemaker) Theory  Metabolic Theory/Caloric Restriction  DNA-Related Research EMERGING THEORIES OF AGING
  • 24.  “…examines the interrelated role of the neurologic and endocrine systems over the life-span of an individual”.  there is a decline, or even cessation, in many of the components of the neuroendocrine system over the lifespan Neuroendocrine Control
  • 25.  “…proposes that all organisms have a finite amount of metabolic lifetime and that organisms with a higher metabolic rate have a shorter lifespan”.  Rodent-based research has demonstrated that caloric restriction increases the lifespan and delays the onset of age-dependent diseases Metobolic Theory of Aging (Caloric Restriction)
  • 26.  Major Developments:  Mapping the human genome (“…there may be as many as 200 genes responsible for contolling aging in humans”)  Discovery of telomeres DNA-Related Research
  • 28. Disengagement Theory Activity/Developmental Task Theory Continuity Theory Age Stratification Theory Person-Environment Fit Theory
  • 29.  Changing FOCUS of Sociological considerations of aging:  60’s focus on losses and adaptation to them  70’s broader global, societal, and structural factors influencing lives of OA’s  80’s-90’s exploration of interrelationships between OA’s and their physical, political, environmental & socioeconomic mileau
  • 30.  Cumming & Henry--1961  Aging seen as a developmental task in and of itself, with its own norms & appropriate patterns of behavior  “appropriate” behavior patterns involved a mutual agreement between Old Aged and society on a reciprocal withdrawal.  No longer supported Disengagement Theory
  • 31.  Havighurst, Neugarten, Tobin ~1963  “Activity is viewed by this theory as necessary to maintain a person’s life satisfaction and a positive self-concept”.  Theory based on assumptions:  1) it’s better to be active than inactive  2) it is better to be happy than unhappy  3) an older individual is the best judge of his or her own success in achieving the first two assumptions Activity Theory (Developmental Task Theory)
  • 32.
  • 33.  How a person has been throughout life is how that person will continue through the remainder of life  Old age is not a separate phase of life, but rather a continuation and thus an integral component Continuity Theory
  • 34.  Riley--1985  Society consists of groups of cohorts that age collectively  The people & Roles in these cohorts change & influence each other, as does society at large  Thus, there is a high degree of interdependence between older adults & society Age Stratification Theory
  • 35.  Lawton, 1982  Individuals have personal competencies that assist in dealing with the environment:  ego strength  level of motor skills  individual biologic health  cognitive & sensory-perceptual capacities  As a person ages, there may be changes in competencies & these changes alter the ability to interrelate with the environment  Significant implications in a society that is characterized by constantly changing technology Person-Environment Fit Theory
  • 36.
  • 37.  Maslow’s Hierarchy of Human Needs  Jung’s Theory of Individualism  Erikson’s Eight Stages of Life  Peck’s Expansion of Erikson’s Theory  Selective Optimization with Compensation PSYCHOLOGIC THEORIES OF AGING
  • 38.  “…each individual has an innate internal hierarchy of needs that motivates all human behaviors”.  depicted as a pyramid; the ideal is to achieve self-actualization, having met all the “lower” level needs successful  “Maslow’s fully developed, self-actualized person displays high levels of all of the following characteristics: perception of reality; acceptance of self, others, and nature; spontaneity; problem- solving ability; self-direction; detachment and the desire for primacy; freshness of peak experiences; identification with other human beings;…….  …satisfying and changing relationships with other people; a democratic character structure; creativity; and a sense of values.  Only about 1% of us are truly ideal self-actualized persons Maslow’s Hierarchy of Human Needs (1954)
  • 39.  Carl Jung--1960  origins are Freudian  Self-realization is the goal of personality development  as individual ages, each is capable of transforming into a more spiritual being Jung’s Theory of Individualism
  • 40. Stages throughout the life course. Each represents a crisis to be resolved.  For OA’s:  40 to 65 (middle adulthood): generativity versus self-absorption or stagnation  65 to death (older adulthood): ego integrity versus despair  Self-absorbed adults will be preoccupied with their personal well- being and material gains. Preoccupation with self leads to stagnation of life”  “Unsuccessful resolution of the last crisis may result in a sense of despair in which individuals view life as a series of misfortunes, disappointments, and failures”. Erikson’s Eight Stages of Life(1993)
  • 41.  Erikson’s last two stages are expanded to 7  The final three of the developmental tasks for old age:  ego differentiation versus work role preoccupation  body transcendence versus body preoccupation  ego transcendence versus ego preoccupation Peck’s Expansion of Erikson’s Theory
  • 42.  Individuals develop strategies to manage losses of function that occur over time  3 Interacting Elements: selection: increasing restriction ofone’s life to fewer domains of functioning optimization: people engage in behaviors to enrich their lives compensation: developing suitable, alternative adaptations Selective Optimization with Compensation -Baltes-1987
  • 43.