6. Types of Channels
● Ligand gated channels
e.g. Na+ channels at N-M Junction
● Voltage gated channels
e.g. Ca++ channels on nerve membrane
7. Functions of cell membrane
• Protection
• Electrical property
• Transports across membrane
(Semipermeable )
• Cell to cell communication
• Movement and phagocytosis
19. Resting Membrane Potential
• The difference in electric potential that
exists across the cell membrane when cell is
in resting state
• Developed due to K ions (-94mV)
Na ions (+ 8mV)
Na-K pump (- 4mV)
25. Properties of action potential
• Propagation
(Impulse- self propagatory A.P.)
• All or none law
• Refractory period
(Short R.P. for skeletal muscle and nerve
Long R.P. for cardiac muscle)
27. Cell to cell communication
• Mediators
– Neurotransmitter
– Local hormone
(either excitatory or inhibitory)
e.g. Neuromuscular transmission
Synaptic transmission