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Anxyolitics& hypnotics
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SEDATIVE/HYPNOTICS ANXIOLYTICS www.freelivedoctor.com
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SEDATIVE/HYPNOTICS ANXYOLITICS GABAergic
SYSTEM www.freelivedoctor.com
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Respiratory Depression Coma/
Anesthesia Ataxia Sedation Anxiolytic Anticonvulsant DOSE RESPONSE BARBS BDZs ETOH www.freelivedoctor.com
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Respiratory Depression Coma/
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GABAergic SYNAPSE GABA
glutamate glucose Cl - GAD www.freelivedoctor.com
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Patch-Clamp Recording of
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CNS Effects (Rate
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Biotransformation of Benzodiazepines
From Katzung, 1998 www.freelivedoctor.com
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GABA ? NE
DA 5-HT ACh (-) (-) (-) (-) (-) ANXIOLYTIC ? SEDATION ? ANTICONVULSANT/ MUSCLE RELAXANT ? www.freelivedoctor.com
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