9. The yolk sac
• No YS in GS >8 mm abnormal
• No embryo in a GS >16 mm abnormal
• No embryo in GS of 25 mm Dx failed pregnancy
• No yolk sac or embryo on 2 scans / 7-10 days apart
= definitive evidence of a failed intrauterine pregnancy
10. Intrauterine Fluid Collection
• MSD of 2-3 mm (GA =4.5-5
weeks)
• -hCG = 1,000-2,000 mIU/mL
gestational sac seen on TVS
• “double decidual sign”
11. Gestational sac : GS
Ultrasound in Obstetrics and
Gynecology, Vol 1
Eberhard Merz
12. First-trimester bleeding
• 27% of pregnancies
• overall risk of miscarriage about 12%
serum HCG levels
clinical
presentation
DDx
18. Absence of cardiac activity in embryo
Normal range of FHR
• 6.2-7 wk = 100-120 BPM
• after 7 wk = 137-144 BPM
Scan mode
• pulsed Doppler beam temperature in tissues
•only M-mode US should be used
Video clips
19. US findings in first-trimester bleeding with
a poor outcome
• Bradycardia (FHR < 100)
• slow growth rate of the
embryo
• abnormally small or large
GS /embryo
• enlarged amniotic cavity
• empty amniotic cavity
• No cardiac activity with
visualization of the amnion
• abnormal size or shape of
the yolk sac
• low position / irregular
shape of GS
• GS volume after 7 weeks
20. Subchorionic hemorrhage
common finding
during the 1st trimester
Moderate - large
subchorinic bleeding
compared to GS size
poor outcome
http://emedicine.medscape.com/article/404971-overview#a4
21. F 32 YO GA = 8 weeks, vaginal bleeding
RPOC =Retained product of conceptus
23. Gestational Trophoblastic Disease -GTD
• First trimester : variable appearance
- a small, echogenic endometrial mass without cystic spaces
- mixed echogenic and cystic material
- DDx hydropic degeneration and retained products of
conception.
• Second trimester : distended endometrial cavity filled with
innumerable small cystic spaces
24. Summary 1st trimester bleeding
• TVS is the study of choice for early pregnancies.
• TAS : useful to assess the amount of free fluid and for
abnormalities beyond the FOV of TVS
• correlate with the quantitative -hCG level & with the
clinical presentation
• The lack of an intrauterine GS does not necessarily
indicate ectopic pregnancy
25. Summary 1st trimester bleeding
• A failed pregnancy :
- GS >25 mm & no yolk sac/ embryo
- an embryo measuring ≥7 mm & no cardiac activity.
• Use M-mode to document embryonic viability and measure
heart rate
• Doppler US should not be used to evaluate a normal early
embryo.
26.
27. Ectopic Pregnancy
• Extrauterine GS with a live embryo = 100%
specific
• Extrauterine tubal ring with central fluid
or + a yolk sac and/or a nonviable embryo
• a complex, extraovarian, extrauterine
mass
• Color Doppler : variable
Color and pulsed Doppler imaging is not
necessarily useful
28. • MRI : unusual ectopic pregnancies, GTD, or vascular
abnormalities, but should not delay urgent or emergent care in an
unstable patient.
• CT may be useful in trauma or acute non-gynecologic pain, for
staging of malignancy, or if MRI is not possible.
34. ACUTE PELVIC PAIN IN THE REPRODUCTIVE
AGE GROUP
• EE >21 mm virtually excludes the possibility of ectopic pregnancy
• Absence of an intrauterine pregnancy when the β-hCG level > 3510
mIU/mL : strongly suggestive of ectopic pregnancy
• TVS should be used whenever possible
• TAS is recommended for larger FOV.
• Doppler imaging should be avoided in the setting of developing
intrauterine pregnancy
• •Low-dose NCE- CT for acute pelvic pain in pregnancy for non-
Gyne condition, 2nd/3rd trimester
35. SECOND & THIRD TRIMESTER BLEEDING
• placenta previa (most common)
• placenta accreta (highest risk of life threatening)
• placental abruption
• vasa previa
36. SECOND & THIRD TRIMESTER BLEEDING
• bloody vaginal discharge (“bloody show”)
• cervical infection or neoplasm
• uterine rupture : severe pain in late pregnancy
(had prior C/S and uterine Sx)
40. F. 36 YO vaginal bleeding Placenta previa?
18 weeks10 weeks
41. Placenta previa
• painless bleeding
• near the end of 2nd- 3rd trimester
• 2.8/1,000 in singleton pregnancies
• 3.9/1,000 in twin pregnancies
• risk factors: age over 30, multiparity, prior C/S, and
prior abortions
42. Placenta previa
4 types:
(1) complete previa—covers the internal os (central or
asymmetric)
(2) partial previa—partially covering
(3) marginal—placental edge going to the internal os
(4) low-lying—to within 2 cm of the internal os
43. • placental edge <2 cm from
internal os
measure placental edge
- internal os distance
• placental edge >2 cm from
internal os exclude placenta previa
• Safety? TVS: safe for previa,
including pt. with vag.
bleeding
• Contraindication to TVS:
incompetent Cx with a bulging amniotic sac/
suspected preterm PROM
Transperineal
US
44. Placenta Accreta
• abnormally adherent to the uterus
• increased C/S
• incidence = 1 in 533 deliveries
RadioGraphics,
http://pubs.rsna.org/doi/abs/10.1148/rg.287085060
46. • Placenta increta : chorionic villi invading the myometrium
• Placenta percreta : penetration of chorionic villi through
the uterus
47. Placenta Accreta: US findings
• loss of the normal retroplacental hypoechoic zone
• localized thinning of the myometrium
• increased vascularity at placental-myometrial interface
on CDUS
48. Placenta Accreta: US findings
• “Numerous coherent vessels” at the placental base:
• inseparable cotyledon (fetal villous) and intervillous
(maternal) circulations with extreme hypervascularity
52. Placental Abruption: US findings
• Thickened, with rounded
bulging
• heterogeneous echotexture
• loss of normal basal plate
interface
• Hematoma: variable
RadioGraphics,
http://pubs.rsna.org/doi/abs/10.1148/rg.295085242
53. Vasa Previa
• umbilical vessels traverse the fetal
membranes in the lower uterine
segment in front of the presenting
part and cross over the internal
cervical os unprotected by the
placental or umbilical cord
• http://vasaprevia.com/
54. Vasa Previa
• high risk of fetal death
• Neurologic deficit due to fetal exsanguination
• Incidence is 1/2,500 deliveries
55. Type 1 velamentous insertion
of the cord
Type 2 succenturiate lobe,
with interconnecting vessels
between it & the main placenta
traversing the internal os
57. Summary
Vaginal bleeding in the 2nd or 3rd trimester ass.
with increased risks Mother & Fetus.
TAS = primary imaging
TVS needed for visualization of Cx & internal os
(+/- transperineal US)
58. Summary : Placenta previa
Decribe distance of the placental edge to the internal os
Reevaluated during pregnancy for a potential resolution
depending on the degree of attachment to the opposing
wall.
59. Summary :Placental abruption
• clinical diagnosis
• emergency US : placental thickening, heterogeneity, and
a periplacental hematoma
60. Summary: Placental accreta
• Prior C/S increase the risk of placental accreta
• US findings: intraplacental lacunes, increased vascularity,
myometrial thinning, and focal placental bulge
• MRI improves Dx confidence
61. Summary: Vasa previa
• Serious risk that needs to be recognized and requires a
planned C/S.
• Velamentous cord insertion VS. interconnecting vessels
of accessory placental lobe (succenturiate lobe), over
internal Cx os