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Innovation in Affordable CD4 Enumeration Diagnostics

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Anand Sivaraman

This presentation details the systematic processes that were employed in understanding various cost components that contribute to the high cost CD4 enumeration reagents. ReaMetrix's dried down technology that enables elimination of cold-chain in storage and shipment of reagents is also discussed.

Santé & MédecineTechnologie
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Innovative, Multi-platform, Affordable CD4+ Enumeration Reagents that Need No Cold Chain: Impacting HIV/AIDS Management in Resource Poor Settings Dr.Anand Sivaraman, ReaMetrix India Pvt. Ltd. Bangalore 560092 ReaMetrix Confidential
HIV in India – Current Status ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],ReaMetrix Confidential
Current Issues with CD4 testing in Resource Poor Settings ,[object Object],[object Object],[object Object],[object Object],ISSUES ReaMetrix Confidential ,[object Object],[object Object],[object Object],[object Object],ReaMetrix APPROACH
Clinical Information Generation – Current Scenario Sample journey and cost accumulation Acquire Process Run Provide Results Transport Collection centre Path Lab Doctor Hospital Centralized Path Lab Syringe/Vacutainer/Overheads Cold chain/Courier Tech Labor + Reagent Capital Equipment Amortization Lab Infrastructure Overheads ,[object Object],[object Object],[object Object],Layers of margin at every step ReaMetrix Confidential
Innovations that helped reduce the cost of CD4 testing ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],ReaMetrix Confidential
Innovation in Product Delivery : Issue of Aging of Blood samples ,[object Object],[object Object],[object Object],CD3 capping ReaMetrix Confidential
Unitized (one test per tube) dried-down format : Eliminating the Issue of Aged Samples ,[object Object],[object Object],[object Object],ReaMetrix Confidential
Simplification of Assay Workflow ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ReaMetrix HIV Reagents Performance Assessment * * * * - values in cells per uL
Building in Robustness in Reagents: Shelf Life exceeds 1 year ,[object Object],[object Object],Stability of ReaMetrix Dried Reagents at Room Temperature : do not require Cold storage ReaMetrix Confidential
ReaMetrix Reagents : Making the difference : Changing the Paradigm ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],ReaMetrix Confidential
In the words of the National Microbiology Reference Lab, Zimbabwe ReaMetrix Confidential
Key Centres who have already Validated Reagents and Published Data from Validation ,[object Object],[object Object],[object Object],ReaMetrix Confidential
Publications & Presentations ,[object Object],[object Object],[object Object],[object Object],ReaMetrix Confidential

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