emergency medications

2.  Vasopressor agent with direct and indirect effect on
the sympathetic system

3.  Indirect effect is by causing the release of
Noradrenaline
 Direct effect is by its action on β and α1 -
adrenoceptors

4.  Positive inotropic effect
 Constricts blood vessels
 Increases peripheral resistance
 Elevates systolic and diastolic blood pressure
 Improves cardiac contractility

5.  Over-dosage may cause severe hypertension, sinus
arrhythmias, myocardial infarction and cardiac arrest.

6.  Knights, K & Kathleen, B 2011, Pharmacology for
health professionals, Chapter 12, Elsevier,
Chatswood, Australia.