This document discusses oral anticoagulants, including coumarin derivatives like warfarin, and newer oral anticoagulants. It provides details on warfarin such as its discovery, pharmacokinetics, interactions, side effects and monitoring. Newer oral anticoagulants discussed include direct thrombin inhibitors like dabigatran and factor Xa inhibitors like rivaroxiban which have advantages over warfarin like predictable pharmacokinetics and no need for routine monitoring. Overall the document reviews both traditional and newer oral anticoagulant options.