1. Successful development programs require measurable results and impacts that are sustained over time, which depend on the quality of program design and implementation. 2. Key challenges in program design include promoting collaboration, flexibility, sustainability, rigorous monitoring and evaluation plans, consideration of implementation options, and addressing cross-cutting issues. 3. Important components of program design are problem analysis, development hypotheses, logical frameworks, results frameworks, performance management plans, identification of appropriate interventions, and structuring public-private partnerships.