Injuries to any of the bones, ligaments, tendons or nerves in the wrist joint can cause pain. Severe arthritis is the most common condition for patients considering a total wrist replacement surgery. Two major categories of arthritis may affect the wrist joint, namely osteoarthritis and rheumatoid or inflammatory arthritis. Post traumatic arthritis is another reason for the onset of osteoarthritis years later after trauma to the joint. Finally another indication for wrist pain and dysfunction includes carpal tunnel syndrome.

1. MediPoint: Total Wrist Reconstruction - APAC Analysis and Market Forecasts
MediPoint: Total Wrist Reconstruction - APAC Analysis and Market Forecasts
Summary
Injuries to any of the bones, ligaments, tendons or nerves in the wrist joint can cause pain. Severe arthritis is
the most common condition for patients considering a total wrist replacement surgery. Two major categories
of arthritis may affect the wrist joint, namely osteoarthritis and rheumatoid or inflammatory arthritis. Post
traumatic arthritis is another reason for the onset of osteoarthritis years later after trauma to the joint. Finally
another indication for wrist pain and dysfunction includes carpal tunnel syndrome.
The TWR market in APAC is expected to only have moderate growth, while TWF will be steady. The market
is based on and will be driven by the rising prevalence of osteoarthritis and the rising aging population.
Countries to watch are India and China, but these markets depend heavily on physician training and the
distribution networks and market entry of major players.
Scope
An overview of arthritis, which includes epidemiology, etiology, symptoms, diagnosis, pathology and
treatment guidelines. Annualized APAC TWR market revenue and future forecasts from 2009 to 2011,
forecast for 7 years to 2018. Investigation of current and future market competition for TWR Insightful review
of the key industry drivers, restraints and challenges as well as predicted impact of key events. Competitor
assessment including device approval analysis and device sales forecasts. Marketed and pipeline product
profiles covering efficiency, safety, clinical study details, device approvals, product positioning and device
sales forecast. Analysis of unmet needs within the market and opportunities for future players. Technology
trends evaluation to assess strength of pipeline. An overview of all devices in development including clinical
study details, design and material selection considerations, efficacy reports, and device approval timelines.
Company profiles including business description, financial overview and SWOT analysis. Coverage of key
market players. Strategic assessment of the TWR device sector through market impact analysis, future market
scenario and company analysis. Direct quotes from Key Opinion Leaders (KOL) as well as orthopedists
Reasons to buy
Understand the trends shaping and driving the APAC TWR Market. Realize device preferences of
physicians who have performed the tests already. Access market sizing, forecasts and quantified growth
opportunities in the APAC TWR Market through 2018. Quantify candidate patient populations to better design
product pricing & launch plans. Drive revenues, formulate effective sales and marketing strategies and gain
in-depth understanding of the competitive landscape. Perform benchmarking analysis of growth opportunities
against currently marketed products. Assess competitiveness of products in market by understanding the
strengths and weaknesses of current competition. Take a comprehensive look at the market's device pipeline
and identify promising, paradigm-shifting products. Create an effective counter-strategy to gain a competitive
advantage against those currently in the market. Organize your sales and marketing efforts by identifying the
market categories and segments that present the best opportunities for growth. What's the next big thing in
APAC TWR market landscape? Identify, understand and capitalize.
table Of Contents
MediPoint: Total Wrist Reconstruction - APAC Analysis and Market Forecasts

2. 1 Table Of Contents
1 Table Of Contents 5
1.1 List Of Tables 11
1.2 List Of Figures 13
2 Introduction 14
2.1 Catalyst 14
3 Disease Overview 15
3.1 Anatomy And Physiology 15
3.2 Pathophysiology 16
3.2.1 Overview 16
3.2.2 Osteoarthritis 16
3.2.3 Rheumatoid Arthritis 17
3.2.4 Carpal Tunnel Syndrome 17
3.2.5 Others 18
3.3 Clinical Presentation 18
3.4 Clinical Outcomes 19
3.4.1 Overview 19
3.4.2 Conservative Therapy 20
3.4.3 Arthroscopic Debridement 20
3.4.4 Proximal Row Carpectomy 20
3.4.5 Total Wrist Fusion 21
3.4.6 Total Wrist Replacement 23
3.4.7 Wrist Fusion Versus Total Wrist Replacement 25
3.5 Epidemiology 27
3.6 Economic Impact 29
3.6.1 Economic Impact Of Treating Arthritis 29
3.6.2 Cost Effectiveness Of Orthopedic Implants 30
4 Competitive Assessment 31
4.1 Total Wrist Implant 31
4.1.1 Overview Of Historical Designs 31
4.1.2 Current Designs 31
4.2 Total Wrist Fusion 44
4.2.1 Overview Of Historical Designs 44
4.2.2 Current Designs 44
MediPoint: Total Wrist Reconstruction - APAC Analysis and Market Forecasts

3. 5 Unmet Needs 53
5.1 Long-term Clinical Data 53
5.2 Limited Product Offerings 54
5.3 Failure And Revision Rate 55
5.4 Minimal Bone Resection And Other Complications 56
5.5 Lack Of Pipeline Products 57
5.6 Need For Better Physician Training 58
6 Pipeline Products 59
6.1 Overview 59
7 Industry Overview 60
7.1 Procedure Volumes 60
7.1.1 Asia-pacific 61
7.2 Market Access 63
7.2.1 Asia-pacific 64
7.3 Reimbursement Trends 65
7.3.1 Japan 65
7.3.2 China 66
7.3.3 India 67
7.4 Regulatory Issues/recalls 67
7.5 Mergers & Acquisitions / Key Partnerships 68
8 Company Profiles 70
8.1 Small Bone Innovation Inc. 70
8.1.1 Overview 70
8.1.2 Portfolio Assessment 70
8.1.3 Swot Analysis 71
8.2 Depuy Synthes International 71
8.2.1 Overview 71
8.2.2 Portfolio Assessment 72
8.2.3 Swot Analysis 72
8.3 Integra Lifesciences Inc. 73
8.3.1 Overview 73
8.3.2 Portfolio Assessment 73
8.3.3 Swot Analysis 74
8.4 Biomet Orthopedics 74
8.4.1 Overview 74
8.4.2 Portfolio Assessment 75
8.4.3 Swot Analysis 75
MediPoint: Total Wrist Reconstruction - APAC Analysis and Market Forecasts

4. 8.5 Medartis Ag 76
8.5.1 Overview 76
8.5.2 Portfolio Assessment 76
8.5.3 Swot Analysis 76
8.6 Acumed 77
8.6.1 Overview 77
8.6.2 Portfolio Assessment 77
8.6.3 Swot Analysis 78
8.7 Tornier N.v. 78
8.7.1 Overview 78
8.7.2 Portfolio Assessment 78
8.7.3 Swot Analysis 79
8.8 Swemac Orthopaedics Ab 80
8.8.1 Overview 80
8.8.2 Portfolio Assessment 80
8.8.3 Swot Analysis 81
8.9 Zimmer Holdings Inc. 81
8.9.1 Overview 81
8.9.2 Portfolio Assessment 82
8.9.3 Swot Analysis 82
8.10 Skeletal Dynamics 83
8.10.1 Overview 83
8.10.2 Portfolio Assessment 83
8.10.3 Swot Analysis 83
9 Market Drivers & Opportunities 84
9.1 Market Drivers 84
9.1.1 Rise In Osteoarthritis 84
9.1.2 Aging 84
9.1.3 Trauma 84
9.1.4 Patient Demand And Awareness 85
9.1.5 Availability Of Long-term Clinical Data 85
9.1.6 Further Technological Advancement 86
9.1.7 Corporate Promotions And Teaching Seminars 87
9.2 Opportunities 87
9.2.1 Expanding Aging And Arthritis Indication 87
9.2.2 Revision Surgery 87
9.2.3 Emerging Markets 88
9.2.4 Capitalizing On Market Fragmentation 88
10 Market Threats & Substitutes 89
MediPoint: Total Wrist Reconstruction - APAC Analysis and Market Forecasts

5. 10.1 Market Threats 89
10.1.1 Slow Technological Advancement 89
10.1.2 Physician Perception And Learning Curve 89
10.1.3 Complications 90
10.1.4 Cost 90
10.1.5 Lack Of Long-term Studies 91
10.2 Substitutes 91
10.2.1 Therapeutic Options And Fusion 91
11 Country Outlooks & Forecasts 92
11.1 Major Markets Overview 92
11.2 Japan 96
11.2.1 Overview 96
11.2.2 Japan Market Analysis 96
11.3 China 97
11.3.1 Overview 97
11.3.2 China Market Analysis 97
11.4 India 99
11.4.1 Overview 99
11.4.2 India Market Analysis 99
12 Appendix 101
12.1 Abbreviations 101
12.2 Bibliography 102
12.3 Report Methodology 108
12.3.1 Overview 108
12.3.2 Coverage 108
12.3.3 Secondary Research 108
12.3.4 Forecasting Methodology 109
12.3.5 Primary Research - Key Opinion Leader Interviews 110
12.3.6 Primary Research - Physician Survey 110
12.3.7 Expert Panel Validation 110
12.4 Physicians And Specialists Included In This Study 111
12.4.1 Dr. Philippe Bellemere 111
12.4.2 Dr. Vikas Gupta, Mbbs, Ms 111
12.4.3 William H. Seitz, Jr., Md 111
12.4.4 Robert M. Szabo, Md, Mph 111
12.4.5 David Warwick, Md, Bm, Dimc, Frcs (orth) 111
12.5 About The Authors 112
12.5.1 Analysts 112
12.5.2 Global Head Of Healthcare 113
MediPoint: Total Wrist Reconstruction - APAC Analysis and Market Forecasts

6. 12.6 About Medipoint 113
12.7 About Globaldata 113
12.8 Contact Us 114
12.9 Disclaimer 114
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MediPoint: Total Wrist Reconstruction - APAC Analysis and Market Forecasts