2. The Boston University Laboratory for
Cardiovascular-Renal Research
Richard Wainford serves as an assistant professor of
pharmacology and medicine at Boston University. In
addition to his teaching duties, Richard Wainford functions
as the principal investigator and director at the Laboratory
for Cardiovascular-Renal Research at the institution.
3. The Boston University Laboratory for
Cardiovascular-Renal Research
The researchers at the Laboratory for Cardiovascular-Renal
Research explore the central neural mechanisms for control
of fluid and electrolyte homeostasis as well as blood
pressure regulation. One of the major accomplishments at
the lab remains the identification of a new brain G-Alpha-i
(2)-subunit protein-gated pathway. This pathway plays an
essential role in the regulation of central sympathetic
outflow.
4. The Boston University Laboratory for
Cardiovascular-Renal Research
At present, researchers at the lab are pursuing several
projects related to the roles of PVN specific G-alpha subunit
protein-gated pathways. One of these projects looks at the
neural control of kidney function in the renal sympathetic
nerves. Another project examines systemic arterial blood
pressure regulation, especially in light of sodium-activated
neuronal activity. Researchers also focused on the activity
of renal sodium transporters and how enhanced
sympathetic outflow and sodium intake affect them in both
salt-resistant and salt-sensitive phenotypes.
