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Embase – Building search strategies 21 March 2012
- 1. Welcome to our Embase webinar! Embase for biomedical searching: Building search strategies Your host: Chris Flemming Your presenter: Ann-Marie Roche
- 2. Need to know • Webinar control panel: • ‘chat’ or ‘ask a question’ for questions and comments • Option for full screen view • Q&A after presentation
- 3. Registering in Embase •Setting up email alerts •Saving your searches 3 •Staying up to date
- 4. Planning your systematic searching Planning the search strategy and process in advance helps you to: f td oumiinno ps y li o t u l io w w l toc me – hneeid btleratis groo •Systematicallyhoc t/estthe g ed/ t e number of highly WyHu nb purs,i a maximum retrieve Doconhe yeaeheneive Ar g t tie relevant references dpr ytudi fc e ou n s? s ecicomio s cific eadin sptypes if c spe ubh ecr ad/ spveo?ecific s o r co br p ses? s answersisea •Extract the relevant s and d there ug f or dr 4
- 6. Embase Content Overview Emtree: Biomedical thesaurus, over 60k terms 1947 1950 1974 2009 Embase: Fully indexed: Over 7,700 journals, 1974- MEDLINE: 2,500 journals unique to Embase, mapped to Embase indexing, 1950- (including MEDLINE Classic) Embase Classic: AIP and In Process: Digitally scanned and Indexing added, from 2009 re-indexed, 1947-1973 Conference Abstracts: Indexing added, from 2009 http://www.embase.com/info/what-is-embase/coverage
- 8. Start with Emtree Search for over 60K terms, including MeSH terms and over 30K drug and chemical terms Click here to search further in an Embase search form, mapping all synonyms. Click here to perform an explosion search, if applicable. 3 x updates per year. www.embase.com/info/emtree for more 8information
- 9. Reviewing an Emtree term Consider the term’s History Take note of any Synonyms listed Look at the CAS registry number(s) displayed Read the entry provided from Dorland’s dictionary, when available 9
- 10. Backposting • Emtree terms changes such as trade name and now generic name – How do you find ALL articles, NOT only those indexed from the date of the new term? • BACKPOSTING!
- 12. Search in specific fields Perform a search in the title and abstract fields. Fields such as Drug Trade name (:tn) and CAS registry number (:rn) may also be searched. 12
- 13. F The most common i type of search filter is for specific l study types. Other t filters include publication type . e http://embase.com/info/User for a list of r Embase study s types with definitions (14). 13
- 14. 78 drug and disease subheadings
- 16. Review Question Find disease management studies for Type II diabetes •Look for your term in Emtree •Use the disease search form for disease subheadings. •Use major focus to limit your results. 16
- 17. Review Question •Tracking the efficacy of saxagliptin in treating diabetes type 2 •Comparing the efficacy/safety of dipeptidyl peptidase 4 inhibitors •Investigate the use of subheadings, such as: ‘Pharmacokinetics’, ‘Adverse Drug Reaction’, ‘Drug Toxicity’ •Use explosion to investigate other depeptidyl peptidase 4 inhibitors 17
- 18. Poll The poll should appear on your screen shortly...
- 19. More drug and disease combination searches Find recent reports of cardiac adverse effects of beta 2 agonists in asthma treatment (e.g. formoterol, salmeterol, indacaterol) 19
- 20. More drug and disease combination searches Are there any risks associated with the administration of antibiotics together with digoxin in a patient with congestive heart failure who has contracted pneumonia? 20
- 21. More drug and disease combination searches Cost effectiveness of treatment with rosuvastatin compared with other statins 21
- 22. Free-text searching tips and tricks • Differences between /de and :de, exact search Vs phrase search. • Truncation and operators, AND, OR, NOT, NEXT, NEAR • Review Index terms and Abstracts for additional terms • Remember to consider variant spellings including British and American spellings and terminology o e.g.,diaper vs nappy; pediatric vs paediatric; otorhinolaryngology vs ear, nose and throat; overuse injury vs repetitive strain injury Refer to http://info.embase.com/helpfiles for more guidance and links to materials such as the Quick User Guide.
- 23. Saving searches • Save in personal folders or share your saved searches. • Edit sub-searches within your main search strategy and re-run • Re-use a save search - #name in future searches
- 24. Registering in Embase •Setting up email alerts •Saving your searches 24 •Staying up to date
- 26. • Q&A will be sent to you by email. • For more information and questions please contact bdtraining@elsevier.com • Our next Embase webinar is scheduled for April 18th and will be an introductory webinar. • Go to www.trainingdesk.elsevier.com/embase for all training related materials Please fill out the survey that appears on your screen after leaving the webinar.
Notes de l'éditeur
- Welcome to this webinar about Embase, my name is Chris and I am your host today. I am here with our Embase expert Ann-Marie Roche. Ann-Marie has a biological background and has delivered Embase training for several years. She works closely with the Embase product team and our customers to understand how Embase provides a solution for many different workflows. Today she will introduce you to Embase, showing you for example how to pinpoint precise biomedical information, set up basic search strategies and how to continuously track the biomedical information.
- What can attendees expect from todays’ session?
- Don’t loose those important searches, register in Embase so you may save your searches or set up email alerts. Registering also means you receive all up to date information such as upcoming webinars.
- Content is key/backbone for Embase (Over 600k conference abstracts) Continue to focus to building up content but also on enhancing functionality and indexing/quality.
- Search Emtree term and all synonyms, with title and abstract fields. Select Free Text search before clicking on search and decide if you want mapping on/off.
- We began to index Diagnostic Test Accuracy last year in Embase. As far as we know, Embase is the only online tool to index this study type.
- Check out http://embase.com/info/helpfiles/search-forms/drug-search/drug-subheadings and http://embase.com/info/helpfiles/search-forms/disease-search/disease-subheadings for subheading definitions.
- Starting with Emtree to find suitable terms/subject headings and then using Disease Search to add subheadings. From Session Results, you can edit in-line by moving your mouse over the search strategy and selecting Edit. Try using /de and :de etc exact search and phrase search. Human/de picks up records where human is in the index field and human:de picks up aspects of human. Selecting human from the Advanced Search form searches /de. When looking for exact journal names, such as biochemistry, use /jt. From the Session Results, we may also Copy to Disease Search form and use major focus. Refer to www.trainingdesk.elsevier.com/embase and the Quick User Guide for more guidance
- Starting with Emtree to find suitable terms/subject headings and then using Drug Search to add subheadings. Search saxagliptin with pharmacokinetics and combine with ‘type 2 diabetes mellitus’ with disease subheading ‘drug therapy’. Go back and search for dipeptidyl peptidase IV inhibitors exploded and combine with disease search. Advanced combine on the Session Results: Last search above NOT saxagliptin search, for example #2 NOT #1.
- Search for ‘beta 2 agonists’ in Emtree and once you find a good term, take to the disease search form and search with subheading ‘adverse drug reaction’ . Now search for ‘cardiovascular disease’ exploded with subheading ‘side effect’ and combine with previous search. You can now show how to set up an email alert.
- We shall take this review question as an example for demonstrating Embase tips. Starting with looking into finding subject headings in Emtree, using indexing and combining with filters. Antibiotic and digoxin with drug comparison AND ‘ congestive heart faliure’ with drug therapy AND Pneumonia Save this search – remove drug therapy from disease and rerun main search Now in session results, remove drug comparison from drug sub-searches and note asterix (indicates which searches have been effected by a change to a related search)– now click on result number to update your search strategy.
- Ask the class how they would approach this search. Guidance: Search for rosuvastatin in drug search form with subheading ‘pharmacoeconomics’ and ‘drug comparison’. Now search for with the same subheadings and do another combination. You can also type both in the drug search form in the same search and use the 2 subheadings indicated above. Review your results. Click on one or 2 to show record view and how you can open all drug terms (including the key subheading additional information).
- We recommend always checking Emtree before setting up your free-text searching to check synonyms etc and consider how the mapping will benefit your search. Explosion searching will also effect the terms included in your search. Differences between /de and :de, this is exact search Vs phrase search. Human/de picks up records where human is in the index field and human:de picks up aspects of human. When looking for exact journal names, such as biochemistry, use /jt. Check out http://embase.com/info/helpfiles/search-hints/command-line for more guidance. Proximity operators are supported such as NEXT and NEAR with truncation and field limits. (symptom* NEAR/5 (headache* OR ‘head ache’)):TI,AB The use of more than one proximity operator in a search is not supported, this is A NEXT B NEXT C ( symptom* NEAR/5 headache NEAR/5 aspirin). You may instead search A NEXT B, then B NEXT C and AND together: symptom*NEAR/5 headache AND headache NEAR/5 aspirin Review Index terms and abstracts for additional terms. When performing free-text searches, remember to consider variant spellings including British and American spellings and terminology e.g., diaper vs nappy; pediatric vs paediatric; otorhinolaryngology vs ear, nose and throat; overuse injury vs repetitive strain injury. Refer to www.trainingdesk.elsevier.com/embase and the Quick User Guide for more guidance
- Antibiotic and digoxin with drug comparison AND Congestive heart faliure with drug therapy AND Pneumonia Save this search – remove drug therapy from disease and rerun main search Now in session results, remove drug comparison from drug sub-searches and note asterix (indicates which searches have been effected by a change to a related search)– now click on result number to update your search strategy. Re-use a named search in a new search. For example you may have a group of #limitstrial AND digoxin
- And once again, don’t loose those important searches, register in Embase so you may save your searches or set up email alerts. Registering also means you receive all up to date information such as upcoming webinars.