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DIAdvisor
Personal Glucose Predictive Diabetes Advisor
                        Jens Ulrik Poulsen (Novo Nordisk, DK)
                        Lucian Nita (Romsoft, RO)
                        Eric Renard (CHU Montpellier, F)




  Take 2 IU
  of insulin                          Lucian Nita
                                       RomSoft,
                       On Behalf of the DIAdvisor
                                 Consortium, EU
                          Funded by FP7, European Commission
The consortium
9 countries
13 partners
3 Universities
3 Hospitals
4 SME’s
2 Large enterprises
1 NGO




                      1. Dept. Information Eng.
                      2. Dept. of clin. and Exp.
                         Med.
About DIAbetes
  •   What?    Chronic hyperglycemia
  •   When?    Constant, for life
  •   Why?     Loss of insulin secretion by pancreatic islets
  •   How?     Insulin therapy
  •   Risks?   Severe vascular damages and
               hypoglycemic events

• In Europe:
  • 22.5 Millions persons affected (WH0, 2002)
  • > 50% undiagnosed => 60 M (IDF, 2004)
Insulin-treated Diabetes Mellitus:
       What do we Aim at ?




                                  BASAL

                          BOLUS
Why is it so Difficult to Reach this Goal ?
       Blood Glucose Variability in Insulin-treated
                      Patients !
Glucose Variability is Manageable by ‘Thoroughly Instructed
       and Driven’ Insulin-treated Diabetic Patients




                                     Education
                                     THE MISSING
                              + Modern insulin delivery
                                             LINK:
                                    + Tight glucose
                               A      monitoring
                                   DIABETES ADVISOR
                                    ON EXPECTED
                                 + Advice providers
                                       CHANGES




          But unexpected events may occur…
DIAdvisor concept
Glucose




                            Prediction



            Ad
               v
           som ise:
               e in take
                   sul
                       in

                                         Time
     Now
DIAdvisor concept




              VITAL
                      SIGNS
DIAdvisor system
DIAdvisor system – Patient Interface
DIAdvisor system – Clinician Interface
DIAdvisor is expected to make
   Life with Diabetes Easier




        RomSoft
       www.rms.ro

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Rom soft - Diadvisor presentation - CodeCamp 10 march 2012

  • 1. DIAdvisor Personal Glucose Predictive Diabetes Advisor Jens Ulrik Poulsen (Novo Nordisk, DK) Lucian Nita (Romsoft, RO) Eric Renard (CHU Montpellier, F) Take 2 IU of insulin Lucian Nita RomSoft, On Behalf of the DIAdvisor Consortium, EU Funded by FP7, European Commission
  • 2. The consortium 9 countries 13 partners 3 Universities 3 Hospitals 4 SME’s 2 Large enterprises 1 NGO 1. Dept. Information Eng. 2. Dept. of clin. and Exp. Med.
  • 3. About DIAbetes • What? Chronic hyperglycemia • When? Constant, for life • Why? Loss of insulin secretion by pancreatic islets • How? Insulin therapy • Risks? Severe vascular damages and hypoglycemic events • In Europe: • 22.5 Millions persons affected (WH0, 2002) • > 50% undiagnosed => 60 M (IDF, 2004)
  • 4. Insulin-treated Diabetes Mellitus: What do we Aim at ? BASAL BOLUS
  • 5. Why is it so Difficult to Reach this Goal ? Blood Glucose Variability in Insulin-treated Patients !
  • 6. Glucose Variability is Manageable by ‘Thoroughly Instructed and Driven’ Insulin-treated Diabetic Patients Education THE MISSING + Modern insulin delivery LINK: + Tight glucose A monitoring DIABETES ADVISOR ON EXPECTED + Advice providers CHANGES But unexpected events may occur…
  • 7. DIAdvisor concept Glucose Prediction Ad v som ise: e in take sul in Time Now
  • 8. DIAdvisor concept VITAL SIGNS
  • 10. DIAdvisor system – Patient Interface
  • 11. DIAdvisor system – Clinician Interface
  • 12. DIAdvisor is expected to make Life with Diabetes Easier RomSoft www.rms.ro

Notes de l'éditeur

  1. Buna ziua, sunt Lucian Nita, project manager la firma RomSoft si in urmatoarele 5 minute voi prezenta proiectul Diadvisor, proiect realizat in cadrul unui consortiu multinational cu finantare europeana. Acest proiect isi propune sa realizeze un instrument de analiza si predictie a evolutiei starii de sanatate a persoanelor ce sufera de diabet, numita si “boala secolului 21”.
  2. Consortiul din care firma RomSoft face parte este format din 13 parteneri de pe intreg cuprinsul Europei, incluzand universitati, spitale, firme mari si mijlocii.
  3. Ce este diabetul? Este o boala cronica ce se manifesta printr-o crestere a concentratiei de glucoza din sange datorata lipsei de insulina din organism. Insulina reprezinta hormonul ce ajuta celulele sa absoarba glucoza din sange si s-o transforme in energie. Din cauze inca necunoscute, pancreasul inceteaza la un moment dat sa produca acest hormon, zaharul din sange nu mai este consumat si pacientul intra in hyperglicemie. Hyperglicemia nu doare, nu se manifesta prin stari deosebite, fapt ce sustine parerea specialistilor ca peste 50% din diabetici nu vin la spital si nu sunt diagnosticati. Totusi, este o boala foarte grava, ce produce efecte ireversibile in timp, efecte ce duc la orbire, sau amputarea membrelor inferioare. Se trateaza prin injectarea periodica in organism a unor cantitati specifice de insulina.
  4. Cum se trateaza diabetul? Prin injectarea unei cantitati de insulina de tip “basal” ce actioneaza pe tot parcursul zilei La care se adauga injectii de insulina rapida sau “bolus” prin care sa se compenseze efectele diferitelor mese luate in timpul zilei
  5. Totusi, pacientul este pus zilnic in fata unei dileme, intrucat nu stie ce cantitate de insulina sa-si injecteze deoarece raspunsul organismului la insulina este foarte variabil, depinzand de o multime de factori ce nu pot fi urmariti. O cantitate prea mica de insulina nu rezolva problema hiperglicemiei, in schimb, o cantitate prea mare duce la efectul invers numit hypoglicemie ce are efecte devastatoare pentru organism.
  6. In principiu un pacient poate sa-si controleze in mod eficient diabetul prin impunerea unei disciplini in ce priveste mesele luate in timpul zilei, activitatea fizica desfasurata sau modul de viata. Dar riscul accidentelor ramane ridicat!
  7. Ideea principala este ca pacientul sa fie alertat in timp util sa-si injecteze o cantitate de insulina atunci cand se estimeaza ca acesta intra in starea de hiperglicemie
  8. In acest scop s-a implementat proiectul Diadvisor ce-si propune sa colecteze continuu datele despre starea pacientului si sa calculeze anumite predictii referitoare la evolutia viitoare a acesteia
  9. Sistemul a fost testat in diverse spitale din Europa, datele culese au fost de asemenea trimise pe un server FTP de unde pot fi downloadate si analizate de echipele de matematicieni din cadrul consortiului.
  10. Aceasta este imaginea afisata de aplicatie pe telefonul mobil al pacientului indicand valoarea glicemiei in ultima perioada, precum si predictia acestei valori pentru perioada viitoare. In caz de pericol de hiperglicemie, pacientul este alertat sa-si injecteze o cantitate calculata de insulina
  11. Toate datele culese sunt salvate intr-o baza de date unica la care se conecteaza doctorul in vederea analizei evolutiei pacientului. Doctorul selecteaza un anumit pacient din baza de date si aplicatia afiseaza toate informatiile specifice acelui pacient ce-l ajuta pe doctor sa-si formeze o imagine corecta despre starea pacientului.
  12. Prin utilizarea aplicatiei Diadvisor viata pacientului devine mult mai simpla, stresul asociat cu urmarirea si prevenirea hiperglicemiei este minim, pacientul avand un instrument de incredere care sa-l sfatuiasca zilnic in legatura cu gestionarea situatiei data de aceasta afectiune. Iar RomSoft este mandra sa va anunte ca este implicata in acest proiect european ce are drept scop imbunatatirea vietii pacientilor si a noastra in general.