The document discusses helical tomotherapy, a form of radiation therapy that uses a rotating x-ray beam. It summarizes a study of 150 patients treated with tomotherapy between 2006-2007 for reasons such as complex tumor geometry or need for image guidance. Setup corrections were often needed based on pretreatment MV CT scans. Treatment times were typically under 25 minutes with minimal increases over time. Tomotherapy allows conformal dose distributions and image-guided radiation for difficult cases near critical organs.
25. Machine Interior Fenwick JD, Tome WA, Soisson ET, Mehta MP, Rock Mackie T. Tomotherapy and Other Innovative IMRT Delivery Systems. Seminars in Radiation Oncology. 2006 Oct ;16(4):199-208.
52. ART: Why ? Due to a change in the contours (e.g. Weight Loss) the actual dose received by the organ can vary significantly from the planned dose despite accurate setup and lack of motion.
60. Craniospinal Radiation Penagaricano JA, Papanikolaou N, Yan Y, Youssef E, Ratanatharathorn V. Feasibility of cranio-spinal axis radiation with the Hi-Art tomotherapy system. Radiotherapy and Oncology. 2005 Jul ;76(1):72-78. Results : When considering D50% and D10%, CSA-TOMO has a dosimetric advantage over CSA-RT for most organs at risk. The body integral dose was higher for the CSA-TOMO plan by approximately 6.5% .
61. Dosimetric Comparison Fiorino C, Dell'Oca I, Pierelli A, Broggi S, Martin ED, Muzio ND, et al. Significant improvement in normal tissue sparing and target coverage for head and neck cancer by means of helical tomotherapy. Radiotherapy and Oncology. 2006 Mar ;78(3):276-282.
62. Dosimetric Comparison Fiorino C, Dell'Oca I, Pierelli A, Broggi S, Martin ED, Muzio ND, et al. Significant improvement in normal tissue sparing and target coverage for head and neck cancer by means of helical tomotherapy. Radiotherapy and Oncology. 2006 Mar ;78(3):276-282.
63. Clinical Results: Bauman et al Bauman G, Yartsev S, Rodrigues G, Lewis C, Venkatesan VM, Yu E, et al. A Prospective Evaluation of Helical Tomotherapy. International Journal of Radiation Oncology*Biology*Physics. 2007 Jun 1;68(2):632-641.