antacid therapy for ulcer

1. ANTACID THERAPY FOR
PEPTIC ULCER
s sarvesh

2. Antacid which neutralize the gastric acid and reduce the ulcer pain
Studies shows antacids and H2 blockers are equal effective .
Such as – Magnesium , aluminium and calcium
Duodenal ulcer occur in absence of acid when the hourly maximum
acid output is < 10mEq

3. Antacid reduce the concentration and total load of acid in the gastric
region by increasing the gastric pH
Antacid inhibit the pepsin activity
Antacid strengthen the mucosal barrier

4. NON SYSTEMIC AGENTS
Magnesium and aluminium preferred
as systemic Antacids .
Sodium bicarbonate for intensive ulcer therapy because it avoid risk
of alkalosis .
Liquid antacids having a greater buffering capacity .
Antacid mixture – aluminium hydroxide and magnesium hydroxide
having sustained action but it will induce diarrhea .
Calcium carbonate – it cause acid rebound and hypercalcemia .(milk
alkali syndrome)

5. Thank you