1. Pharmacology II
Chapter 33

2. Drug Classes
• Antacids
• H2 Receptor Antagonists
• GI Prostaglandins
• Proton Pump Inhibitors
• Prokinetics Agents
• Antispasmodic Agents

3. Antacids
• Aludrox
• Baking soda
• Di-Gel
• Gelusil
• Maalox
• Mylanta
• Phillips Milk of Magnesia
• Rioopan
• Titralac
• Tums

4. H2 Receptor Antagonists
• Cimetidine Tagmet
• Ranitidine Zantac
• Nizatidine Axid
• Famotidine Pepcid
• Dizziness headache somnolence
• Diarrhea constipation
• SERIOUS: confusion, disorientation,
hallucination, gynecomastia Hepatoxicity!

5. GI Prostaglandins
• Misoprostol Cytotec
• Diarrhea dose related after 2 wks. of therapy
– Minimized by taking with meals, avoid Mg+
antacids, & @ bedtime
• Pregnancy

6. Proton Pump Inhibitors
• Esomeprazole Nexium
• Lansoprazole Prevacid
• Omeprazole Prilosec
• Pantoprazole Protonix
• Rabeprazole Aciphex
• Constipation dry mouth dizziness

7. Prokinetic Agents
• Metoclopramide Reglan
• Drowsiness fatigue lethargy dizziness
• SERIOUS: Extrapyramidal symptoms

8. Antispasmodic Agents
• Atropine
• Belldonna
• Dicyclomine Bentyl
• Glycopyrrolate Robinul
• Mepenzolate Cantil
• Methscopolamine Pamine
• Propantheline Pro-Bathine
• Scopolamine Scopace
• Blurred vision constipation urinary retention dry mouth,
nose, throat
• SERIOUS: confusion, depression, nightmares, hallucinations
• Orthostatic hypotension!!