Classical drug associations MRCP.

1. Classic Drug association in MRCP DR.SHERIF BADRAWY

2. Psychosis 1a Dr. Sherif Badrawy Digitally signed by Dr. Sherif Badrawy DN: cn=Dr. Sherif Badrawy, o=KKUH, ou=Critical Care, email=sherif_badrawy@ya hoo.com, c=SA Date: 2015.03.23 10:45:36 +03'00'

3. ◥ levodopa ◥ corticosteroids 1b

4. Increased risk of venous thromboembolism 2a

5. ◥ combined oral contraceptive pill ◥ tamoxifen ◥ antipsychotics 2b

6. increased risk of endometrial cancer 3a

7. Tamoxifen 3b

8. Flushing 4a

9. ◥ amlodipine ◥ sildenafil ◥ tamoxifen 4b

10. Mucositis 5a

11. ◥ methotrexate ◥ fluorouracil (5-FU) 5b

12. Fluid retention 6a

13. ◥ pioglitazone ◥ ciclosporin ◥ corticosteroids ◥ hydralazine 6b

14. Peripheral neuropathy 7a

15. ◥ vincristine,vinblastine,cisplatin ◥ isoniazid ◥ amiodarone ◥ phenytoin ◥ etanercept 7b

16. haemorrhagic cystitis 8a

17. Cyclophosphamide 8b

18. Carbimazole 9a

19. myelosuppression/agranulocytosis 9b

20. Primaquine 10a

21. haemolysis in patients with G6PD deficiency 10b

22. Toxicity in patients with thiopurine methyltransferase deficiency 11a

23. azathioprine 11b

24. Thrombocytopaenia 12a

25. ◥ heparin ◥ sodium valproate ◥ thiazides ◥ valproic acid ◥ quinidine 12b

26. antagonist of the P2Y12 adenosine diphosphate (ADP) receptor 13a

27. Clopidogrel 13b

28. acetazolamide 14a

29. Normal anion gap metabolic acidosis 14b

30. Sumatriptan - contraindicated by: 15a

31. ischaemic heart disease 15b

32. tendon damage 16a

33. Ciprofloxacin 16b

34. acts as a decoy receptor for TNF- alpha 17a

35. Etanercept 17b

36. Prevents microtubule depolymerisation & disassembly, decreasing free tubulin 18a

37. docetaxel 18b

38. Inhibits formation of microtubules 19a

39. vincristine 19b

40. Intracranial hypertension 20a

41. ◥ isotretinoin ◥ corticosteroids 20b

42. Pulmonary, retroperitoneal and cardiac fibrosis 21a

43. bromocriptine 21b

44. glucagon-like peptide-1 mimetic 22a

45. Exenatide 22b

46. increased risk of fractures 23a

47. ◥ Pioglitazone ◥ heparin ◥ bisphosphonates ◥ corticosteroids 23b

48. Adenosine - contraindicated by: 24a

49. asthma 24b

50. Weight gain 25a

51. ◥ sodium valproate ◥ sulfonylureas ◥ pioglitazone ◥ lithium ◥ antipsychotics ◥ corticosteroids 25b

52. decreases IL-2 release by inhibiting calcineurin 26a

53. Ciclosporin - 26b

54. Causes cross-linking in DNA 27a

55. cisplatin 27b

56. Oculogyric crisis 28a

57. ◥ antipsychotics ◥ metoclopramide 28b

58. Metformin Monitoring 29a

59. review if creatinine is > 130, stop metformin if > 150 29b

60. ACE inhibitors Monitoring 30a

61. Acceptable ↑ in serum creatinine , up to 50% from baseline or up to 265 (whichever is smaller) & an increase in potassium up to 5.5 30b

62. oesophagitis 31a

63. Bisphosphonates 31b

64. liver fibrosis 32a

65. Methotrexate 32b

66. 5-HT3 antagonist 33a

67. Ondansetron - 33b

68. Increased risk of ischaemic stroke 34a

69. ◥ combined oral contraceptive pill ◥ antipsychotics 34b

70. Hypomagnesaemia 35a

71. cisplatin 35b

72. torticollis 36a

73. Antipsychotics 36b

74. slate-grey appearance 37a

75. Amiodarone 37b

76. Anal ulceration 38a

77. nicorandil 38b

78. Increased risk of cervical cancer 39a

79. combined oral contraceptive pill 39b

80. Sildenafil - contraindicated by: 40a

81. recent myocardial infarction 40b

82. Aspirin in breastfeeding 41a

83. must be avoided 41b

84. Corneal deposits 42a

85. ◥ amiodarone ◥ antipsychotics 42b

86. irreversible blockade of H+/K+ ATPase 43a

87. Omeprazole - 43b

88. Metformin - contraindicated by: 44a

89. recent myocardial infarction 44b

90. Palpitations 45a

91. ◥ levodopa ◥ hydralazine ◥ adenosine 45b

92. Akathisia (severe restlessness) 46a

93. antipsychotics 46b

94. Red man syndrome 47a

95. vancomycin 47b

96. Epistaxis 48a

97. ◥ isotretinoin (dt dryness) ◥ warfarin 48b

98. Reactivation of tuberculosis 49a

99. ◥ corticosteroids ◥ infliximab ◥ etanercept 49b

100. recombinant version of urate oxidase 50a

101. Rasburicase - 50b

102. Depression 51a

103. ◥ isotretinoin ◥ corticosteroids ◥ levodopa 51b

104. Hypertrichosis 52a

105. ◥ ciclosporin ◥ minoxidil 52b

106. Cinchonism 53a

107. quinidine 53b

108. Thrombophlebitis 54a

109. ◥ amiodarone ◥ vancomycin 54b

110. Impotence 55a

111. thiazides beta-blockers 55b

112. Pruritus 56a

113. ◥ opioids ◥ fenofibrate 56b

114. Hypocalcaemia 57a

115. ◥ loop diuretics ◥ foscarnet 57b

116. Skin necrosis 58a

117. warfarin 58b

118. anticoagulant which don't cross-react é HIT Abs 59a

119. ◥ Danaparoid ◥ Lepirudin ◥ Argatroban 59b

120. Oligospermia 60a

121. sulphasalazine 60b

122. urinary retention 61a

123. ◥ Tricyclic antidepressants ◥ antipsychotics ◥ chlorpheniramine61b

124. Proximal myopathy 62a

125. corticosteroids 62b

126. Hypothyroidism 63a

127. ◥ amiodarone ◥ lithium ◥ carbimazole 63b

128. Blocks T-type calcium channels in thalamic neurons 64a

129. ethosuximide 64b

130. Binds to TNF-alpha and prevents it from binding with TNF receptors 65a

131. infliximab 65b

132. Anti-CD20 monoclonal antibody 66a

133. rituximab 66b

134. Decreases absorption of fat-soluble vitamins 67a

135. cholestyramine 67b

136. Osteoporosis 68a

137. ◥ corticosteroids ◥ heparin ◥ pioglitazone 68b

138. Mania 69a

140. Competitive antagonist of nicotinic acetylcholine receptors 70a

141. atracurium 70b

142. Myalgia 71a

143. ◥ statins ◥ fenofibrate 71b

144. Dopamine receptor agonist 72a

145. ◥ ropinirole ◥ apomorphine ◥ bromocriptine ◥ cabergoline 72b

146. Acetylcholinesterase inhibitor 73a

147. ◥ donepezil ◥ pyridostigmine ◥ galantamine ◥ rivastigmine ◥ edrophonium 73b

148. inhibits RANK ligand, which in turn inhibits the maturation of osteoclasts 74a

149. Denosumab - 74b

150. Insomnia 75a

152. Tachycardia 76a

153. ◥ isosorbide mononitrate ◥ hydralazine ◥ minoxidil 76b

154. Neuroleptic malignant syndrome 77a

155. antipsychotics 77b

156. Anorexia 78a

157. ◥ levodopa ◥ digoxin ◥ interferon-alpha 78b

158. Optic neuritis 79a

159. ethambutol 79b

160. Non-arteritic anterior ischaemic neuropathy 80a

161. sildenafil 80b

162. coarsening of facial features 81a

163. Phenytoin 81b

164. Pneumonitis 82a

165. ◥ amiodarone ◥ methotrexate 82b

166. Bronchospasm 83a

167. ◥ beta-blockers ◥ adenosine 83b

168. Hypertension 84a

169. ◥ corticosteroids ◥ ciclosporin 84b

170. Inhibits microtubule polymerization by binding to tubulin, interfering with mitosis. Also inhibits neutrophil motility and activity 85a

171. colchicine 85b

172. Metabolised to the active compound mercaptopurine, a purine analogue that inhibits purine synthesis 86a

173. azathioprine 86b

174. potassium-channel activator 87a

175. Nicorandil - 87b

176. bivalirudin 88a

177. Reversible direct thrombin inhibitor 88b

178. Activates antithrombin III. Forms a complex that inhibits thrombin, factors Xa, Ixa, Xia and XIIa 89a

179. unfractionated heparin 89b

180. Bladder cancer 90a

181. pioglitazone 90b

182. Suppression of growth in children 91a

184. Steven-Johnson syndrome 92a

185. ◥ lamotrigine ◥ carbamazepine 92b

186. Increased risk of breast cancer 93a

188. MAO-B inhibitor 94a

189. selegiline 94b

190. COMT inhibitor 95a

191. ◥ entacapone ◥ tolcapone 95b

192. Inhibits sodium absorption at the beginning of the distal convoluted tubule 96a

193. bendroflumethiazide 96b

194. Blocks the action of cyclooxygenase-1 and 2 and thromboxane A2 formation 97a

195. aspirin 97b

196. Hyperprolactinaemia 98a

197. ◥ antipsychotics ◥ metoclopramide 98b

198. Enhance the effect of the inhibitory neurotransmitter gamma- aminobutyric acid (GABA) 99a

199. benzodiazepines 99b

200. Alopecia 100a

201. ◥ sodium valproate ◥ valproic acid 100b

202. Increased risk of myocardial infarction 101a

204. Constipation 102a

205. ◥ antipsychotics ◥ verapamil ◥ tricyclic antidepressants ◥ opioids 102b

206. Apomorphine 103a

207. dopamine receptor agonist 103b

208. Retinopathy 104a

209. hydroxychloroquine 104b

210. Slurred speech 105a

211. ◥ antipsychotics ◥ phenytoin ◥ amantadine 105b

212. Gout 106a

213. ◥ thiazides ◥ pyrazinamide ◥ loop diuretics ◥ nicotinic acid 106b

214. Blurred vision 107a

215. ◥ antipsychotics ◥ tricyclic antidepressants ◥ ivabradine ◥ chlorpheniramine 107b

216. Gingival hyperplasia 108a

217. ◥ phenytoin ◥ ciclosporin ◥ amlodipine ◥ diltiazem ◥ verapamil 108b

218. Dyskinesia 109a

219. ◥ levodopa ◥ antipsychotics ◥ phenytoin 109b

220. Photosensitivity 110a

221. ◥ amiodarone ◥ tetracyclines ◥ isotretinoin ◥ thiazides 110b

222. Nasal congestion 111a

223. sildenafil 111b

224. Ototoxicity 112a

225. ◥ loop diuretics ◥ aminoglycosides ◥ vancomycin 112b

226. Ataxia 113a

227. ◥ phenytoin ◥ sodium valproate ◥ carbamazepine ◥ amantadine 113b

228. Dry mouth 114a

229. ◥ isotretinoin ◥ tricyclic antidepressants ◥ levodopa ◥ antipsychotics ◥ chlorpheniramine 114b

230. Hypoglycaemia 115a

231. ◥ sulfonylureas ◥ meglitinides 115b

232. Heart failure 116a

233. ◥ verapamil ◥ diltiazem 116b

234. Dry skin 117a

235. isotretinoin 117b

236. Cartilage damage 118a

237. ciprofloxacin 118b

238. pyrimidine analogue which induces cell cycle arrest and apoptosis by blocking thymidylate synthase 119a

239. Fluorouracil (5-FU) - 119b

240. discolouration of teeth 120a

241. Tetracyclines 120b

242. Osteonecrosis of the jaw 121a

243. bisphosphonates 121b

244. Blocks the release of acetylcholine 122a

245. Botox 122b

246. Heart block 123a

247. ◥ verapamil ◥ diltiazem ◥ ivabradine ◥ adenosine ◥ digoxin 123b

248. Hirsutism 124a

249. ◥ phenytoin ◥ corticosteroids 124b

250. growth hormone receptor antagonist 125a

251. Pegvisomant - 125b

252. agonist of the A1 receptor in the AV node 126a

253. Adenosine - 126b

254. Hypokalaemia 127a

255. ◥ thiazides ◥ loop diuretics ◥ amphotericin B 127b

256. Stimulates alpha adrenergic, dopaminergic and serotonergic receptors resulting in uterine contractions 128a

257. ergometrine 128b

258. Blocks the uptake of dopamine, noradrenaline and serotonin 129a

259. cocaine 129b

260. Crystalline nephropathy 130a

261. aciclovir 130b

262. Confusion 131a

263. ◥ digoxin ◥ amantadine ◥ phenytoin ◥ metoclopramide 131b

264. Haemolysis in patients with G6PD deficiency 132a

265. ◥ primaquine ◥ ciprofloxacin ◥ sulphonamides ◥ sulphasalazine ◥ sulfonylureas 132b

266. Meglitinides MOA 133a

267. increase pancreatic insulin secretion 133b

268. non-specific phosphodiesterase inhibitor and decreases cellular uptake of adenosine 134a

269. Dipyridamole - 134b

270. Pancreatitis 135a

271. ◥ corticosteroids ◥ sodium valproate ◥ thiazides ◥ valproic acid 135b

272. Facilitate GABAA action by increasing the duration of chloride channel opening 136a

273. barbiturates 136b

274. Yellow-green vision 137a

275. digoxin 137b

276. Arachidonic acid product causing vasoconstriction & increased platelet aggregation 138a

277. TXA2 138b

278. Lymphadenopathy 139a

279. phenytoin 139b

280. Tremor 140a

281. ◥ lithium ◥ ciclosporin ◥ sodium valproate ◥ antipsychotics 140b

282. Sumatriptan - contraindicated by: 141a

283. cerebrovascular disease 141b

284. Inhibits GABA transaminase 142a

285. valproic acid 142b

286. Increased susceptibility to severe infection 143a

287. ◥ corticosteroids ◥ ciclosporin 143b

288. Hyponatraemia 144a

289. ◥ thiazides ◥ loop diuretics ◥ sulfonylureas ◥ carbamazepine ◥ sodium valproate 144b

290. Non-specific inhibitor of phosphodiesterase resulting in an increase in cAMP 145a

291. theophylline 145b

292. Increases cGMP leading to smooth muscle relaxation 146a

293. ◥ isosorbide mononitrate ◥ hydralazine 146b

294. Antagonises the effects of vitamin K 147a

295. warfarin 147b

296. Gynaecomastia 148a

297. spironolactone 148b

298. Drug-induced lupus 149a

299. ◥ hydralazine ◥ procainamide ◥ hydralazine ◥ phenytoin ◥ carbamazepine ◥ tetracyclines ◥ isoniazid 149b

300. Disulfiram-like reaction with alcohol 150a

301. metronidazole 150b

302. Nephrotoxicity 151a

303. ◥ ciclosporin ◥ aminoglycosides ◥ amphotericin B ◥ foscarnet ◥ vancomycin ◥ loop diuretics 151b

304. HER2/neu receptor antagonist 152a

305. trastuzumab 152b

306. Respiratory depression 153a

307. ◥ benzodiazepines ◥ opioids 153b

308. Reduced seizure threshold 154a

309. ◥ ciprofloxacin ◥ antipsychotics ◥ foscarnet 154b

310. Dizziness 155a

311. ◥ phenytoin ◥ carbamazepine ◥ amantadine ◥ nicorandil 155b

312. Hyperlipidaemia 156a

313. ◥ isotretinoin ◥ corticosteroids ◥ ciclosporin ◥ protease inhibitors ◥ antipsychotics 156b

314. Lipodystrophy 157a

315. ◥ protease inhibitors ◥ corticosteroids 157b

316. Cholesterol gallstones 158a

317. ◥ cholestyramine ◥ fenofibrate 158b

318. Bradycardia 159a

319. ◥ amiodarone ◥ beta-blockers ◥ digoxin ◥ verapamil ◥ diltiazem ◥ ivabradine 159b

Classical drug associations MRCP.

Recommandé

Recommandé

Contenu connexe

Tendances

Tendances (20)

En vedette

En vedette (20)

Similaire à Classical drug associations MRCP.

Similaire à Classical drug associations MRCP. (20)

Dernier

Dernier (20)

Classical drug associations MRCP.