1. PREDICTION OF IMPULSE CONTROL DISORDERS IN
PARKINSON’S DISEASE USING MACHINE LEARNING
TECHNIQUES
A PROJECT REPORT
SUBMITTED IN PARTIAL FULFILLMENT OF THE
REQUIREMENTSFOR THE AWARD OF THE DEGREE OF
MASTER OF TECHNOLOGY
IN
VLSI DESIGN AND EMBEDDED SYSTEM
submitted by:
SHWETA
(2K21/VLS/18)
Under the supervision of
DR. RAJESH ROHILLA
(Professor)
DEPARTMENT OF ELECTRONICS AND COMMUNICATION
ENGINEERING
DELHI TECHNOLOGICAL UNIVERSITY
(Formerly Delhi College of Engineering)
Bawana Road, Delhi - 110042
JUNE 2023
2. i
DEPARTMENT OF ELECTRONICS ANDCOMMUNICATION
ENGINEERING
DELHI TECHNOLOGICAL UNIVERSITY
(Formerly Delhi College ofEngineering)
Bawana Road,Delhi-110042
CANDIDATE’S DECLARATION
I, SHWETA, Roll No. 2K21/VLS/18 student of M.Tech (VLSI Design & Embedded
system), hereby declare that the project dissertation titled “Prediction of impulse
control disorders in Parkinson's disease Using Machine learning techniques”
which is submitted by me to the Department of Electronics and Communication
Engineering, Delhi Technological University, Delhi in partial fulfillment of the
requirement for the award of the degree of Master of Technology, is original and not
copied from any source without proper citation.
Place: Delhi SHWETA
Date: 28.05.2023 (2K21/VLS/18)
3. ii
DEPARTMENT OF ELECTRONICS ANDCOMMUNICATION
ENGINEERING
DELHI TECHNOLOGICAL UNIVERSITY
(Formerly Delhi College of Engineering)
Bawana Road, Delhi-110042
CERTIFICATE
I hereby certify that the Project Dissertation titled “Prediction of impulse control
disorders in Parkinson’s disease Using Machine learning techniques” which is
submitted by SHWETA, 2K21/VLS/18 (Department ofElectronics & Communication
Engineering), Delhi Technological University, Delhi in partial fulfillment of the
requirement for the award of the degree of Master of Technology,is a record of the
project work carried out by the student under my supervision.
Place: Delhi Prof. Dr Rajesh Rohilla
Date: 28.05.2023 Department of ECE
4. iii
ACKNOWLEDGEMENT
A successful project requires not only the efforts of the person to whom the project is
assigned, but also the assistance and supervision of others who assisted in the project's
completion. I'd like to express my gratitude to everyone who has assisted us in this
researchand motivated me throughout my studies.
With profound sense of gratitude, I thank Prof. Dr.Rajesh Rohilla, my Research
Supervisor, for his encouragement, support, patience and guidance in this project
work. I heartily appreciatethe guidance given by him in the project presentation that has
improved my presentation skills with her comments and advices. I am overjoyed to
express my gratitude to my family and friends for their assistance throughout this
undertaking.
SHWETA
Roll no: 2K21/VLS/18
5. iv
ABSTRACT
Non-engine side effects are normal in Parkinson's disease (PD) and incorporate
impulse control disorders (ICDs). This was the essential assessment to include cross-
endorsement and replication in an independent accomplice to evaluate the estimate addressing
things to come pace of these sicknesses using longitudinal data. Techniques: The preparation
set included information from two longitudinal Parkinson's illness associates. Drive for
Parkinson's Movement Markers, or PPMI; test bunch: DIGPD, Prescription Joint effort With
Characteristics in Parkinson's Affliction). We included 380 PD members from PPMI and 388
PD subjects from DIGPD in our examination. The two gatherings had somewhere around two
visits and approached both clinical and hereditary information. Using clinical bet factors and
inherited assortments as of late associated with ICDs, we arranged three key backslides and a
monotonous cerebrum association to predict ICDs at the going with visit. Execution was
estimated utilizing the typical accuracy and area under the receiver operating characteristic
curve (ROC AUC). We stood out these models from a direct model that anticipated ICDs in
view of the state of the latest visit. On the two assistants, the monotonous cerebrum
association (PPMI: 0.85 [0.80 - 0.90], DIGPD: 0.802 [0.78 - 0.83]) fared better compared to
the direct model (PPMI: 0.75 [0.69 - 0.81] is the ROC AUC; DIGPD: 0.78 [0.75 - 0.80]). In
foreseeing ICDs in Parkinson's sickness, we exhibited that a repetitive brain network model
beats an essential model. With PPMI information, the improvement as far as ROC AUC was
more noteworthy than with DIGPD information, however nor gathering's improvement was
clinically critical. Ends: ML techniques might be valuable for anticipating ICDs, as indicated
by our discoveries, however clinical pertinence will require extra examination.
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TABLE OF CONTENTS
CERTIFICATE ........................................................................................................ii
ACKOWLEDGEMENT..........................................................................................iii
ABSTRACT.............................................................................................................iv
TABLE OF CONTENTS..........................................................................................v
LIST OF FIGURE..................................................................................................vii
CHAPTER 1 INTRODUCTION...........................................................................1-4
SOFTWARE REQUIREMENT....................................................................1
HARDWARE REQUIREMENT ..................................................................2
CHAPTER 2 FEASIBILITY STUDY ..................................................................4-6
ECONOMIC FEASIBILITY ........................................................................5
TECHNICAL FEASIBILITY .......................................................................5
SOCIAL FEASIBILITY...............................................................................6
CHAPTER 3 LITERATURE SURVEY .............................................................7-10
CHAPTER 4 SYSTEM ANALYSIS.................................................................11-13
EXISTING SYSTEM .................................................................................11
DISADVANTAGES OF EXISTING SYSTEM..........................................11
PROPOSED SYSTEM ...............................................................................11
ADVANTAGES OF PROPOSED SYSTEM ..............................................12
FUNCTIONAL REQUIREMENTS............................................................12
NON FUNCTIONAL REQUREMENTS....................................................12
CHAPTER 5 SYSTEM DESIGN......................................................................14-22
SYSTEM ARCHITECTURE........................................................................14
UML DIAGRAM..........................................................................................16
CHAPTER 6 IMPLIMENTATION..................................................................23-26
MODULES...................................................................................................23
SAMPLE CODE...........................................................................................25
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CHAPTER 7 SOFTWARE ENVIRONMENT.................................................27-32
CHAPTER 8 SYSTEM TESTING ...................................................................33-36
TESTING STRATEGIES .............................................................................33
TEST CASES ...............................................................................................36
CHAPTER 9 SIMULATION ............................................................................37-39
CHAPTER 10 CONCLUSION ..............................................................................40
REFERENCES ..................................................................................................41-42
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CHAPTER 1
INTRODUCTION
Albeit the engine side effects of Parkinson's disease (PD) are the most notable,
the disease has likewise been related with different non-engine side effects. ICDs are
psychological instabilities depicted by an inability to go against a drive and inadequate
undertakings to control explicit approaches to acting. ICDs and the issues that
accompany them are normal in Parkinson's sickness. Cross-sectional examinations
report a predominance of 15-20%, yearly rates of generally 10%, and combined
frequencies of more than half in longitudinal examinations following five years of
disease. Individuals who have Parkinson's infection for over five years are impacted
by these issues. Psychotic wagering, pointless eating, and rash shopping are the four
most unavoidable ICDs in Parkinson's affliction, yet other ordinary ICDs consolidate
punding and hobbyism, and the pace of each ICD, particularly fanatical wagering,
contrasts exceptionally among social orders. ICDs should be tended to straightaway
since they are connected to a lower personal satisfaction, stressed relational
associations, and a more prominent weight on parental figures. Various contextual
analyses recommend that ICDs disappear when individuals quit taking dopamine
agonist (DA) drugs, either somewhat or totally. ICDs in Parkinson's illness have been
connected to various factors, including socio-segment, clinical, and hereditary
markers. Neurotic betting and hypersexuality problems are more normal in men, while
enthusiastic shopping and dietary issues are more normal in ladies. In various
investigation, more energetic age has been associated with ICDs in Parkinson's
disease. Uneasiness, pity, and anomalies in rapid eye movement (REM) rest conduct
have likewise been connected to ICDs. The essential gamble factor for ICD has been
recognized as dopamine substitution treatment.
SOFTWARE REQUIREMENTS
Programming essentialities are troubled about appearance current fashion
property and essentials that bear identify on a PC accompanying present highest in
rank protest of a program. More often than not, these environments or essentials
10. 2|Page
should come together alone before the program can convene taking everything in
mind the reality that they are usually not piece of the part endowment pack.
Platform – A chapter in enrolling is a somewhat foundation, either working or
prioritize, that authorizes the use of prioritize. The plan of a PC, allure functioning
whole, or compute tongues and their runtime athenaeums are cases of ordinary stages.
While naming makeup needs, individual of the chief measures resolved is
active plan (compute). For sure, even while few level of in proper sequence about
resemblance is now and then stopped informed about latest trends, set up can not be
realistic accompanying moderate histories of approximate accumulation of occupied
wholes. For instance, most Microsoft Windows XP uses achieved't attempt Microsoft
Windows 98, nevertheless the backward isn't be guaranteed to solid. On Linux
disseminations utilizing Part differences v2.2 or v2.4, compute fashioned utilizing
later parts of the number looks out for not run or total exactly (or by any means shape
or form).
APIs and drivers – Programming that powerfully applies distinguishing gear,
exemplification, first in class show connectors, demands unambiguous APIs or later
maneuver motorists. A extraordinary outline is DirectX, plenty APIs for directing
synthesized television connected satisfies, specifically game happening, on Microsoft
stages.
Web browser – The adulthood of netting requests and compute that completely relies
upon Web incident use bureaucracy's secret default program. No matter what the
imperfections in ActiveX controls, Microsoft Web Voyager is a notable piece of set
up that surprising pierce favorite for the Windows occupied makeup.
HARDWARE REQUIREMENTS
The honest PC money, incessantly unspoken as gear, are ultimate familiar
method of points of interest defined by some functioning structure or set up program.
11. 3|Page
An hardware compatibility list (HCL) is usually contained accompanying a look of the
principal gear, exceptionally when occupied foundations are complicated. For the
active construction or request, a HCL represents gear parts that have happened
scrutinized, are acceptable, and unpredictably are not. The miscellaneous details of
fittings necessities are hidden in the accompanying socially subsections.
Architecture – Each functioning scheme for a PC is renovate to the PC crafty. The
ample most of compute programs have express occupied structure and compositional
needs. Despite the fact that skilled are saved from arrangement occupied structures
and tasks, the most concede possibility be recompiled to require an alternate plotting.
Furthermore, explore a summary of unusual active foundations and the models that
help bureaucracy.
Processing power – A calculating main part of computer accompanying an enough
attractive care of layoff should happen again for some request. In x86-located uses, the
PC meat killer's model and alarm speed address a detracting unspecified moment of
truth gone hooking up accompanying capacity. Transport speed, store, and MIPS are
referring to a specifically known amount PC meat killer traits that impact killing and
capacity still are with determination overlooked. As AMD Athlon and Intel Pentium
pertaining to a focus processors occasionally have divergent throughput speeds at
corresponding timer speeds, this significance of capacity is usually assorted up. Since
they are a important unspecified moment of truth examined about attending and have
proficient an influential group of celebrity.
Memory – A PC's random-access memory (RAM) is where everything is helped
when it is used. Thought needs are open upon seeing the request's solicitations,
occupied plan, friend tasks and records, and various single phases. While last this
models, high-quality show of added minor uses handling a gambling out many tasks
PC method is additionally hope of.
Secondary storage – The diameter of the program groundwork, the amount of brief
records transported and grasped all along compute institution or custom, and the
rational use of exchange room all impact by virtue of what much hard plate room
necessary (it is lacking to (want RAM).
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Display adapter – Best in class show connectors are a meaningful few still very
uncertain in the form necessities of prioritize like plans editors and extreme level trick
that demand a show accompanying greater PC outlines than the average.
Peripherals – Some part programs need the intense and additionally clear use of
specific element, that demands the better show or ability of those part. These element
mix belongings like center of activity, indicating devices, Collection ROM drives, and
friendship novelty.
13. 5|Page
CHAPTER 2
FEASIBILITY STUDY
The project's sensitivity is evaluated at this stage, and a crucial work plan and
a few cost forecasts provide a foundational understanding. During the design
evaluation, it is essential to investigate the proposed structure's rationality. This will
guarantee that the organization will not encounter any issues as a result of the
proposed method. It is fundamental to have an intensive comprehension of the center
requirements for the system of the possibility study.
The following three factors have an impact on the feasibility study:
ECONOMICAL FEASIBILITY
This evaluation aims to determine the improvement's financial impact on the
alliance. The group has a predetermined number of resources to contribute to the
framework's creative endeavor. A money demand should be utilized to screen the
charges. The created system was under monetary arrangement since a great deal of the
upgrade was public space. It was planned that only those particular items would be
bought.
TECHNICAL FEASIBILITY
The structure's unique requirements or accessibility are the focus of this
evaluation. Any created plan shouldn't cause a lot of issue for the mechanical
resources that might be gotten to. In accordance with this, the quantity of mechanical
assets that are available will be vigorously emphasized. The customer will break the
rules in this way. Since its execution just expects close to zero alterations, the made
construction ought to be of little significance.
14. 6|Page
SOCIAL FEASIBILITY
The client's familiarity with the framework is the primary focus of the survey. The
client's planned method of system use is included in this. The customer shouldn't think
that the framework makes it hard for them to come to an equitable agreement; Instead,
they ought to think that it is necessaryin light of everything. One of the most
significant factors that influences the customers' level of affirmation is the method
used to educate and change them about the system. He ought to have his conviction
overturned because he is the actual user of the system. He will be able to conduct a
private, voluntary inspection because of this.
15. 7|Page
CHAPTER 3
LITERATURE SURVEY
Caregiver burden and the nonmotor symptoms of Parkinson’s
disease:https://pubmed.ncbi.nlm.nih.gov/28802929/
As per Chaudhuri and Schapira (2009), Parkinson's disease has for quite some
time been believed to be essentially a development issue. Regardless, obviously the
heaviness of nonmotor symptomatology influences carer weight and individual
fulfillment (Benavides, Alberquerque, and Chana-Cuevas, 2013; (2011) Martinez-
Martin As Parkinson's infection propels, nonmotor aftereffects, despite motor
incidental effects, become practically irrefutable. As their condition advances, patients
need more support, which is commonly given by a casual guardian, regularly a mate
or relative (Martinez-Martin, Forjaz, Frades-Payo, et al., 2007). As well as being
costly and tedious, the guardian position is inwardly, genuinely, and psychosocially
requesting. The expense of care is fundamentally conveyed by the family, and as
demonstrated by one study, the typical carer wears through 22 hours out of each and
every week completing their commitment. The parental figure has a remarkable and
favored perspective on the patient's state as a result of indifference, mental weakness,
and wretchedness side effects. Thus, they may habitually give a more exact
assessment of the patient's side effects and the viability of treatment. Subsequently, it
is fundamental for the parental figure to take part in clinical visits and treatment
choices whenever the situation allows. This section will underline the significance of
ahead of schedule and progressing commitment with the guardian as well as the effect
that nonmotor side effects have on the parental figure. The story will be mixed with
carer contemplations as experienced by Jon Hiseman while really focusing on his
significant other Barbara, an incredibly famous saxophonist. Further examination
concerning the effect of a few significant nonmotor side effects on parental figure
weight will be directed.
16. 8|Page
Impulsive and compulsive behaviors in Parkinson’s disease:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231987/
Impulsive and compulsive behaviours (ICBs) are an alternate grouping of
infections that may be conveyed by Parkinson's disease (PD) long-term dopaminergic
replacement therapy (DRT). Dopamine dysregulation syndrome (DDS), punding, and
impulse control disorders (ICDs). Contents: the study of disease transmission,
pathophysiology, clinical qualities, risk variables, finding, and treatment of ICBs were
all completely inspected by us. Results: The frequency of ICBs in Parkinson's sickness
patients goes from 3 to 4 percent for DDS, 0.34 to 4.2% for punding, and 6 to 14
percent for ICDs, with a more noteworthy pervasiveness in Western societies than
Asian ones. DDS is more normal in individuals who take a great deal of levodopa, and
ICDs are firmly connected to dopamine agonists. Different subtypes of ICBs share
various gamble factors, like a male orientation, higher levodopa identical everyday
dose, more youthful age at PD beginning, a drinking history, and an incautious or
curiosity looking for character. The Survey for Rash Routine Issue in Parkinson's
Disease Rating Scale is apparently a supportive gadget for social event important
information from patients and carers. ICB treatment is as yet a major issue for
specialists. DRT rearrangement keeps on being the most famous technique. Abnormal
antipsychotics, antidepressants, amantadine, and psychosocial treatments are likewise
used to control psychosis episodes brought about by urgent DRT. Be that as it may,
keeping ICB side effects and engine anomalies in balance is significant. Also,
significant brain sensation of the subthalamic center might be a promising way for
adjusting ICBs. End: It is as yet unclear what accurate pathophysiological processes
ICBs go through in Parkinson's illness. In addition to the fact that it is important to
direct extra examination to grasp the pathophysiology, pervasiveness, qualities, risk
factors, and pathophysiology of ICBs, yet in addition to foster treatments that are
powerful for individuals who are encountering these awful impacts.
Prevalence of repetitive and reward-seeking behaviors in
Parkinson disease:https://pubmed.ncbi.nlm.nih.gov/16957130/
297 individuals with Parkinson's disease (PD) were assessed utilizing severe
definitional standards and methodical screening techniques. 2.4% of individuals in the
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course of their life had pathologic hypersexuality. 0.7% of individuals were inclined to
enthusiastic shopping. When gotten together with our pathologic wagering data, the
lifetime transcendence of these approaches to acting was 6.1%, climbing to 13.7% in
dopamine agonist patients.
Impulse control disorders in Parkinson disease: A cross-
sectionalstudy of 3090
patients:https://pubmed.ncbi.nlm.nih.gov/20457959/
Groundwork investigation has revealed an association between dopamine-
replacement treatment and impulse control disorders (ICDs) in Parkinson's disease
(PD). Targets: Gauge the point commonness of four ICDs in Parkinson's sickness and
examine how they connect with dopamine substitution treatment and other clinical
attributes. Cross-sectional assessment with stupefied raters to PD remedy status and a
derived chose reviewing process for subject enrollment. people: 46 development
problem focuses in the US and Canada gave normal clinical treatment to 3900
individuals with treated idiopathic Parkinson's sickness. The essential result measures
were the Minnesota Rash Issues Interview score for urgent sexual way of behaving
and buying, the Massachusetts Betting Screen score for flow issue/neurotic betting,
and the examination rules for voraciously consuming food problem from the
Indicative and Factual Manual of Mental Problems. The discoveries uncovered that
13.6% of patients had an ICD, with 3.9% having at least two ICDs and 5.0% betting,
3.5% urgent sexual way of behaving, 5.7% impulsive buying, and 4.3% gorging
problem. Issues with drive control were more normal in patients treated with
dopamine agonists than in patients not treated with dopamine agonists (17.1% versus
6.9%; 2.72 chances proportion (OR); 95% confidence interval [CI], 2.08-3.54; P.001).
The event of inspiration control mix was equivalent for pramipexole and ropinirole
(17.7% versus 15.5%; OR, 1.22; 95% CI, 0.94-1.57; P =.14). ICDs were freely
connected with levodopa use, being in the US, being more youthful, being single,
presently smoking, and having a family background of betting issues. Ends: In
Parkinson's sickness, dopamine agonist treatment is connected to a 2-to 3.5-overlay
improve in the probability of fostering an ICD. Cross-ICD drug class connect is
apparent in this relationship. Other fragment and clinical factors' relationship with
ICDs uncover a bewildered affiliation that needs more examination to smooth out
insurance and treatment attempts.
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Longitudinal analysis of impulse control disorders in Parkinson
disease:https://pubmed.ncbi.nlm.nih.gov/29925549/
The goal of this study was to look at the long part influence relationship
between dopamine replacement treatment and impulse control disorders (ICDs) in
Parkinson's disease (PD). Strategies: We utilized data from a multicenter longitudinal
companion of back to back Parkinson's infection patients who had been distressed for
a considerable length of time at the hour of the review's initiation and were followed
yearly for the accompanying five years. ICDs were assessed in semistructured eye to
eye interviews with improvement mix trained professionals. Summed up assessing
conditions and Poisson models with strong change were utilized to explore the
association between ICDs at each visit and numerous time-subordinate meanings of
dopamine agonist (DA) utilization, including measurements and length of treatment.
Other antiparkinsonian prescriptions were also analyzed. The results showed that 356
(86.6%) of 411 patients (40.6% women, mean age 62.3 years, ordinary ensuing 3.3
years, SD 1.7 years) had taken a DA something like once since infection start. The 5-
year consolidated event of ICDs in 306 individuals without ICDs at benchmark was
46.1% (95% confidence interval [CI] 37.4-55.7, DA ever clients 51.5% [95% CI 41.8-
62.1], DA never clients 12.4% [95% CI 4.8-30.0]). Following five years, the
predominance of ICD expanded from 19.7% toward the starting to 32.8%. Before,
there was a relationship between's ICD use and DA use (predominance proportion
4.23, 95% CI 1.78-10.09). ICDs were independently related with lifetime ordinary
regular portion and treatment length, with huge piece influence connections.
Comparative investigations on levodopa didn't track down a critical connection. ICDs
continuously vanished after DA was finished. End: In this longitudinal investigation
of Parkinson's sickness patients getting a high level of DA treatment, the 5-year total
frequency of ICDs was 46%. Portion impact connections between's DA use and ICDs
were found; Expanded term and measurement were connected to ICDs. ICDs
progressively vanished after DA was finished.
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CHAPTER 4
SYSTEM ANALYSIS
EXISTING SYSTEM
ICDs in Parkinson's sickness have been connected to various factors, including
socio-segment, clinical, and hereditary markers. Obsessive betting and issues are more
normal in men, while impulsive shopping and dietary problems are more normal in
ladies. In various investigation, more young age has been associated with ICDs in
Parkinson's ailment. Uneasiness, misery, and irregularities in rapid eye movement
(REM) rest conduct have likewise been connected to ICDs. The essential gamble
factor for ICD has been recognized as dopamine substitution treatment. ICDs have
been connected to both levodopa and dopamine agonists, with dopamine agonists
having an increasingly strong association. At last, ICDs have been connected to a
couple of single-nucleotide polymorphisms (SNPs) in qualities engaged with the
dopamine flagging pathway. There has not been a great deal of consideration paid to
the prescient capacities of these parts all in all. Patient-level expectations were given
by just three investigations. The makers of every one of the three assessment used
clinical and inherited data to set up an essential backslide and a while later attempted
its gauge limit using the area under the receiver operating characteristic (ROC) curve
(ROC AUC). In these examinations, there was no replication associate or cross-
approval, which brought down trust in the expressed execution.
DISADVANTAGES OF EXISTING SYSTEM
In all these studies, there was no replication cohort or cross-validation, which
lowered confidence in the claimed performance.Impulse control disorders (ICDs) are
mental infections set apart by the powerlessness to oppose a drive and the inability to
manage specific ways of behaving.
Proposed System
Foreseeing ICDs from clinical and genomic information utilizing ML
calculations was our essential goal. The models were prepared and cross-approved on
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one companion utilizing two longitudinal accomplices, and their speculation
capacities were tried on the other associate all the while. The goal was to foresee the
probability of ICDs at the accompanying arrangement utilizing the patient's hereditary
data and clinical history.
Advantages of proposed system
ML calculations might be valuable in foreseeing ICDs.
Based on the patient's clinical history and genotyping data, predict the likelihood of
ICDs at the subsequent visit.
FUNCTIONALREQUIREMENTS
NON-FUNCTIONALREQUIREMENTS
The quality component of a product framework is alluded to as a NON-
FUNCTIONAL REQUIREMENT (NFR). They survey the item structure considering
its responsiveness, accommodation, security, mobility, and other non-helpful
characteristics that are indispensable to its success. " How rapidly does the site open?
is an outline of a necessity that doesn't work. Non-viable essentials that are not met
may provoke structures that don't fulfill the solicitations of the clients. You can restrict
or limit the framework's design across different dexterous accumulations utilizing non-
useful prerequisites. For example, the site ought to stack in three seconds assuming
that there are in excess of 10,000 simultaneous guests. Portraying non-useful
prerequisites as completely as practical requirements is important.
22. 14|Page
CHAPTER 5
SYSTEM DESIGN
SYSTEM ARCHITECTURE
Fig.5.1.1 System architecture
DATA FLOW DIAGRAM
1. A DFD frame another name puzzling over a DFD. It a important graphical
etiquette sure preserve pass secondhand through design seeing describe a
scaffolding in wording about dossier it gets, dealing with it acts on distinguishing
dossier, also towards dossier it produces as result.
2. One about most essential exhibiting gadgets data stream outline (DFD). It's used
through address system's an immense number. skeleton process, data used through
process, an external substance certain imparts among system, in addition towards
information streams in skeleton continue models about these parts.
3. DFD depicts how information flows through skeleton in addition towards changed
through a progression about changes. It's a graphical depiction about data stream
23. 15|Page
in addition towards changes certain happen when data goes starting contribution
through yield.
4. DFD was occasionally suggested as an air pocket chart by method thinking. At
any level about discussion, a DFD protect beat utilized through strategy
considering portray a framework. DFD protection is broken down into levels, with
each level focusing on a more important level in the information stream and viable
detail.
Fig.5.1.3 Dataflow diagram
24. 16|Page
UML DIAGRAMS
Unified Modeling Language (UML) a truncation considering "Bound together
Modeling Language." In space about object-arranged programming, UML a
standardized extensively helpful showing language. Object Management Group in
charge about standard, in addition via it endure conveyed through them.
The goal considering UML through method considering transformed into a standard
language considering making object-arranged programming models. UML has two
fundamental parts in its continuous construction: a meta-model in addition via a
documentation. Some sort about procedure or process could get past added to, or
related with, UML in future.
The Unified Modeling Language (UML) a standard language considering
portraying, imagining, working, in addition via revealing programming system relics,
as well as business showing in addition via other non-programming structures.
The UML a collection about best planning deals among considering showing huge in
addition via complex structures certain have been appeared through work.
The UML an essential part about object-arranged programming improvement in
addition via programming improvement process. through method considering express
arrangement about programming projects, UML basically uses graphical
documentations.
GOALS
Coming up next persist essential objectives about UML plan:
1. Give clients among a prepared to-utilize visual demonstrating language
certainpermits them through make plus offer significant models.
2. Give components considering expanding plus practicing key ideas.
3. Get through indifferent about specific programming dialects or advancement
processes.
4. Lay out a proper establishment considering grasping demonstrating language.
5. Advance development about market considering OO instruments.
6. Empower use about more significant level advancement thoughts like coordinated
efforts, systems, examples, plus parts.
7. Apply brilliant practices.
25. 17|Page
Use Case Diagram
A construction for a use case diagram that has not yet been fully resolved was
also used to initiate a UML use-case assessment. Its goal through offer a graphical
depiction about a structure's convenience in phrasing about performers, targets
(imparted as use cases), in addition via any circumstances between those usage cases.
A use case diagram's central point through show which system limits persist
performed pondering which performer. occupations about structure's performers
preserve overcome shown.
Importing the packages
Exploring the dataset
Data processing
Splitting the data into train & test
User
Building the model
Training the model
User signup & signin
User input
Final outcome
Fig.5.2.1 Usecase diagram
26. 18|Page
Class Diagram
The class outline was applied using a measure use case chart and the counted
plan determined by the foundation. In a secondhand case chart, performers are
separated into a collection of relevant classes using a class diagram. The distinction
between "is-a" and "has-a" continues to hold in connection or network tween classes.
Class capacities continue to be referred to as class "techniques," and each class in the
class diagram maintains proficiency through knowledge of all clear acts. Aside
commencing that, each class might have some "credits" certain recognize it
commencing others.
Fig.5.2.2 Class diagram
27. 19|Page
Activity diagram
The action chart portrays how framework's cycles stream. A movement graph
has exercises, activities, changes, introductory plus last states, plus gatekeeper
conditions, very much like a state chart.
Fig.5.2.3 Activity diagram
28. 20|Page
Sequence diagram
The collaboration between unmistakable items in skeleton addressed through a
grouping graph. A succession chart's most huge element certain it time-requested.
previously mentioned implies certain careful request in which things collaborate
portrayed advance through advance. arrangement chart's different components impart
among each other through passing "messages.".
importing the packages
Fig.5.2.4 Sequence diagram
System
User
Exploring the dataset
Data processing
Splitting the data into train & test
Model building - SVM, RF, DT, LR, XGBoost, Voting classifier, RNN and GRU
Training the model
User signup & signin
User input
Prediction
29. 21|Page
Component diagram
The part frame portrays design's more basic level parts. The recent outline
demonstrates the components that make up the skeleton and how they are connected
on a large scale. After the skeleton has progressed or the building stage has continued,
the parts that died are depicted in a section frame.
Fig.5.2.6 Component diagram
Collaboration diagram
The communications between things persist gathered in a participation graph.
communications persist recorded as numbered connections, which makes it more
straightforward through means of follow arrangement about occasions. cooperation
chart helps among distinguishing proof pretty much all potential connections between
things.
Splitting the datase
t into train & test
Importing
libraries
Prediction
User input
User signu
p & sgnin
Training the
model
Building the
model
Data
processing
Exploring
the dataset
30. 22|Page
1: importing the packages
2: Exploring the dataset
3: Data processing
4: Splitting the data into train & test
5: Model building - SVM, RF, DT, LR, XGBoost, Voting classifier, RNN and GRU
6: Training the model
7: User signup & signin
8: User input
9: Prediction result
User System
Fig.5.2.5 Collaboration diagram
Deployment diagram:
The application's runtime components' planned lifespan can be seen in the
organization graph. Using a get-through, a skeleton can be created and prepared, and
the above chart is extremely helpful.
Fig.5.2.7 Deployment diagram
System
User
31. 23|Page
CHAPTER 6
IMPLEMENTATION
MODULES
Data exploration: using aforementioned module we will load data into system
Processing: Using module we will read data considering processing
Splitting data into train & test: using aforementioned module data will be
divided into train & test
Model generation: Model building - SVM, RF, DT, LR, XGBoost, Voting
classifier, RNN and GRU. Accuracy calculated
User signup & login: Using aforementioned module will get registration &
login
User input: Using aforementioned module will give input considering
prediction
Prediction: final predicted displayed
ALGORITHMS
SVM: Support Vector Machine (SVM) is a directed order of machine learning that
maybe employed for reversion and categorization. They are best adapted for
categorization,despite we concern bureaucracy as reversion issues. In an N-spatial
scope, the objective of the SVM invention search out establish a hyperplane that
plainly categorizes the recommendation points.
RF:A Random Forest method (RF) is a controlled ML procedure namely mainly
promoted in ML for arrangement and relapse issues. We are knowledgeable that
32. 24|Page
skilled are plenty saplings in a thicket, and the more wood skilled are, the more
forceful the wood is.
DT: A non-parametric directed knowledge system famous as a decision tree (DT)
maybe appropriated in reversion and categorization tasks. A root bud, arms, within
knots, and leaf growth constitute allure hierarchic seedling building.
LR: Logistic regression (LR) is an ML arrangement blueprint that forecasts the
feasibility of specific classes taking everything in mind driven subordinate
determinants. In a nutshell, the logistic regression model increases the traits of the
recommendation to reckon the logistic of the effect (skilled is usually a bias
component).
XGBoost:XGBoost is a fashionable and active open-beginning resolution for slope-
pushed forests. Gradient pushing is a system of directed education that attempts to
correctly think a aim changing by joining the estimates of a group of tinier, feebler
models.
Voting Classifier: A vote classifier is an ML judge that prepares differing base
models or assessors and anticipates on account of the results of each base judge.
Amassing principles maybe connected representative selections for each judge yield.
RNN: A type of neural network popular as recurrent neural network (RNN) uses the
amount of the former step as recommendation for the current step. Sequence
categorization, emotion categorization, and broadcast categorization are ultimate
average requests for RNNs. Examples of order branding contain chosen individual
acknowledgment and one talk tagging.
GRU: In few positions, the Gated Recurrent Unit (GRU) is a type of recurrent neural
network (RNN) that has benefits over long short term memory (LSTM). GRU is
active and uses less thought than LSTM; However, when handling best series datasets,
LSTM is more correct.
35. 27|Page
CHAPTER 7
SOFTWARE ENVIRONMENT
PYTHON LANGUAGE
Python is an efficiently pertaining to syntax, object-organized, giant level,
interpreted set up speech. In light of charm demonstrated level explicit dossier
structures, dynamic making, and dynamic restricting, it is explicitly captivating for
Quick Application Improvement likewise to the reach that charm propensity as a
status or stick writing to facilitate existent parts. The expense of program support is
abridged by Python's justifiable accentuation on understandability. When projects are
removed and discussed once more, Python's support for modules and assortments
governs everything. The Python judge and the entire standard athenaeum are literally
interchangeable and available as a starting point or duplicate scenario for each
comprehendible foundation. Due to the allure of governing proficiency, most designs
in moment of truth have overwhelming Python tendencies. Because there is no
drawing stage, the change test-interrogate phase is remarkably intelligent. Python
programs are simple to examine due to the convention that a bug or incorrect
information will never cause separation hindered anticipation to be successful. Right
when the translator finds an impression, it raises of best comparable condition
pondering total. The interpreter comes from the stack in the event that the request does
not take the single case. Using a starting level debugger, you can streak at discord
explanations, set breakpoints, decide close by and typically determinants, go line by
line through the law, and look at different parts. Python's solidarity uproar mind is
demonstrated each debugger, that is formed in Python. Of course, the most effective
and quickest way to evaluate a program in terms of the dupe test-check era out is to
increase referring to a specifically known number of print clarifications to the
beginning law.
Python is a perplexing, cost-free, interactive, active, and fundamentally
prioritized programming language. Procedural and object-collecting PC making
programs are stopped informed of the most recent trends. Because Python is a
36. 28|Page
uniquely designed sound, we are forbidden from displaying the component. For
instance, in the current situation, x = 10, where x might be a type that is equivalent to
a String or an int.
Features in Python:There are numerous Python components, some of which are
discussed below:
1. Open Source and Free
By tapping the Download Python knob in the load associate below, you can sign in
to the Python priority word for free. You will be taken to the capacity webpage via
this. Despite the odds, the majority of Python users also investigate the beginning
law because Python is open-source. From expert on, you can load, use, and close it.
2. Easy to code
The majority of the time, Python is a fundamental setup language. Python is much
simpler to learn than other programming languages like C, C#, Javascript, and so on.
Because Python is a vocabulary with a high priority, it typically moves quickly or in
days. The design will also be useful to fashion designers.
3. Easy to Read
Python is easy to learn, as might be expected. Python's supplement is authentically
fundamental, as of late composed. The law block's signification is carried by spaces
rather than divisions or semicolons.
4. Object-Oriented Language
One of Python's most important climaxes is the ability to design PC programs in an
item-located manner. Modified classes, object representation, and additional Python-
systematized prose plans provide support.
5. GUI Programming Support
You can create graphical user interfaces in Python by utilizing a pack like PyQt5,
PyQt4, wxPython, or Tk. PyQt5 is the utilized final, or graphical use foundation, for
Python.
37. 29|Page
6. Python is a high-level programming language
Python makes it irrelevant to screen the occurrence's sythesis or control thought
when making uses.
7.Extensible feature
A language that could be shared is Python. After Python has been convinced into
either individual or the different C or C++, we can use C or C++ to draw Python
regulations.
8.Easy to Debug
Excellent shadings to avoid making a mistake. Before you can check Python errors,
you'll need to find and fix the majority of them quickly. By looking at it, you can
figure out what the rule should basically do.
9. Python is a portable programming language
Python is a standard for dealing with setup jargon that may have been addressed in
some place. To run it on Linux, Unix, or a Macintosh, we won't need to alter the
Python rule in any way after making it for Windows.
10. Python is a language with integration
Python is also a related language because it is easy to include various jargons like C,
C++, and so on with Python.
11. Language Interpreted
Python is a referee sound taking everything in mind the case that allure rule is
proved line by line. As opposite to rule inscribed indifferent accents like C, C++,
Java, etc, Python rule doesn't need assembling, making it more unequivocal to
research. A after methods is captured while changeful over Python's beginning rule
into bytecode.
38. 30|Page
12. Large Standard Library
You achieved't should form some law not enough your own cause Python matches a
monumental standard bibliotheca that integrates various modules and limits.
Standard clarifications, whole experiment, netting uses, and miscellaneous aspects
are essential for the talkative Python book repository.
13. Dynamically Typed Language
You can insert in a novel manner thanks to the Python setup sound. due to the fact
that it selects the type (int, bifold, long, thus.). A changeable's type does not need to
open or spread out over a long period of time due to this component, but it is
preferred at run time.
14. Development of the frontend and backend
Python plans for HTML can be executed and created using clear, unambiguous parts
like "py-handwriting," "py-env," and so on that come with the new attempt "py
handwriting." Thusly, you will in a real sense be going to finish jobs for Python front-
end progress that are almost similar from Java penmanship. Allure backend is one of
Python's best materials; Through its use of the Django and Carafe frameworks, this
work rarely promotes it.
15. Allocating Memory Dynamically
In Python, the need to select the realities fairly the evolving is overwhelming. When
a value is distributed for a change at runtime, thought course occurs. Software
engineers should create the int y = 18 because they are able to simply introduce the
value y=18 and comprehend that each number 15 is assigned to y.
LIBRARIES/ PACKGES:
Tensorflow
TensorFlow is a register study that can be used for a variety of dataflow and setup
needs and is free and open-source. Like a delegate numerical review for played
dossier, front facing skin network demands Google involves it for both judgment and
well disposed procedures all the while. For use inside Google, the Google Cerebrum
39. 31|Page
pack fashioned TensorFlow. On November 9, 2015, it was created approachable under
the Apache 2.0 open-beginning grant.
Numpy
The bundle the chiefs register vocabulary Numpy is usually secondhand. It offers a
accumulation object accompanying a lot, extraordinary speed, and the strength to
work together these shows.It is the essential rational communicable care of piece for
Python. It has various traits, containing the matching elementary one:
Instruments for mixing C/C++ and Fortran law
A powerful N-hide bunch object
Present day (telecom) capabilities
Steady straight polynomial arithmetic, Fourier change, and contradictory
number limits
Regardless of what allure realistic rational uses, Numpy is dependable settings for a
sever news owner. Numpy's talent to open some dossier types create it feasible for
Numpy to fast and really talk accompanying an far-reaching level of educational
records.
Pandas
Pandas, an open-beginning Python book repository, gives peerless killing dossier
control and evaluation apparatuses by utilizing allure broad dossier constructions.
Most of moment of truth, Python was appropriated for preprocessing and munging
dossier. It touched the dossier search. Pandas understood the plan completely. Pandas
can be used to finish the five standard models of news handling and testing, but the
dossier's fountain: plan, alter, model, and distinguish Python and Pandas are turned to
in different expert and expert fields, containing financial issues, evaluations,
assessment, consequently.
Matplotlib
In different honest plans and cross-stage intelligent scenes, Matplotlib, plenty Python
2D scheming novelty, produces plans of uneven character. The Python and IPython
structures, the Jupyter Scratch cushion, netting request servers, and Python content are
40. 32|Page
surely uphold by Matplotlib's four graphical UI device compartments. Using
Matplotlib, you can handle experiment endeavors and complicate one. Each somewhat
plot, graph resembling pie, capacity ranges, bar frame, disorder outline, and
distributing plot maybe steal two or three lines of rule. Models maybe in the direction
of the condensed shows and model plots.
When appropriated accompanying IPython, the pyplot bunch gives a MATLAB-like
partnership point for fundamental plan. With compliments to ruling belongings like
line styles, content style backgrounds, center point features, etc, the capacity customer
has two selections: a act attracted connect or an variety of MATLAB-considerate
methods.
Scikit – learn
Scikit-learn offers a difference of matched and free knowledge methods through a
normalized Python connect. It is open under a generous BSD-located grant and is
applicable under various Linux dispersals, that form it auxiliary for two together
educational and trade purposes.
41. 33|Page
CHAPTER 8
SYSTEM TESTING
System testing is a method of quality assurance (QA) that examines how
various application components contribute to the development of an organized
foundation or request. Building experiment mix form level experiment and foundation
compromise experiment have various names. A program's building is tried to
guarantee it everything particularly as wonted. The comfort of an request inserts as the
bedrock for this foundation, what competencies as a somewhat flight data recorder
experiment. For instance, foundation experiment commit research to check either each
somewhat customer recommendation further forges request killing.
Phases of system testing
A broadcast manual for this level of the test. Structure testing takes a glance by
any means facets of an request to guarantee it everything overall. After beneficial or
customer account experiment of individual modules and meld experiment of each part
have existed done, a QA group usually acts scheme experiment.
In the event that an part build meets the conditions of building experiment, it
uses up individual last evaluation through profit experiment superior to ongoing on
toward invention, place customers will promote the article. All flaws are inspected by
an use bettering group, that figures out that types and the number of are OK.
Software Testing Strategies
Upgrading the method is high-quality methods for spending money the
reasonability of PC set up experiment. An part experiment plan displays what, when,
and by what method to complete entirety anticipated to give an peerless concluding
consequence. The following set up testing wholes and their blends are usually used to
realize this important objective:
42. 34|Page
Static Testing
In the latent points of experiment, changeless experiment is exploited to handle
the article outside surely exploiting it. As a rule, this table hindering is important for
pursueing defects and issues in the real rule. Set-up experiment is outrageous seeing
the habit that it obstructs issues agreeable on by systematize blunders and fundamental
flaws in latest fashion.
Structural Testing
Without being run, process can't be adequately tried. The white-box
experiment, also known as the fundamental experiment, is crucial for identifying and
resolving issues and deviations arising throughout the current fashion and improving
the pre-concoction stage of the era. Utilizing lapse experiment and observing the
program's development, unit experiment is immediately achieved. In most cases, a
43. 35|Page
reworked method incorporated into the test science is used at this point to accelerate
the improvement of ideas by designing analogous mechanical systems foundation.
Because they have unrestricted access to the most recent fashion's happening and facts
streams, makers and QA designers are able to test some changes (change experiment)
in the design's habit of handling acting. This is done by isolating the effects of the
tests from those of earlier differences (control stream experiment).
Behavioral Testing
The latest round of testing centers less around these significant times and more
on what the program's kickbacks changed from the start fulfills on or in a
transportation object. As a result, the lead experiment, also known as the "dirty-box
experiment," entails carrying out various manual tests to ascertain the article from the
perspective of the customer. QA plans usually have few particular dossier about an
union or various clarifications behind the program, that is allude to as "the flight data
recorder," to lead comfort tests, for instance, and answer issues likewise that usual
customers of the article would. Lead experiment concede possibility similarly
combine motorization (lapse tests) to omit human blunder, it be necessary to
acknowledge that difficult appointments. For instance, if you want to see how the
article handles a particular attempt, you will need to fill out 100 conscription forms in
person. Mechanization is famous for this test.
48. 40|Page
CHAPTER 10
CONCLUSION
As per our discoveries, Parkinson's disease related deficiencies in drive control
can be expected. In any case, the increments over a basic model are lacking to
legitimize clinical utility at this level of study. In any case, this study lays out a pattern
against which resulting examination can measure up and shows great method. To
make clinically accommodating models, more investigation including other bet factors
and surveying the beginning of ICDs are fundamental.
49. 41|Page
REFERENCES
[1] J. P. Hiseman and R. Fackrell, “Caregiver burden and the nonmotor symptoms
of Parkinson’s disease,” Int. Rev. Neurobiol., vol. 133, pp. 479–497, 2017.
[2] A. H. Evans, A. P. Strafella, D. Weintraub, and M. Stacy, “Impulsive and
compulsive behaviors in Parkinson’s disease,” Movement Disord.: Official J.
Movement Disord. Soc., vol. 24, no. 11, pp. 1561–1570, 2009.
[3] V. Voon et al., “Prevalence of repetitive and reward-seeking behaviors in
Parkinson disease,” Neurology, vol. 67, no. 7, pp. 1254–1257, 2006.
[4] D. Weintraub et al., “Impulse control disorders in Parkinson disease: A cross-
sectional study of 3090 patients,” Arch. Neurol., vol. 67, no. 5, pp. 589–595,
May 2010.
[5] J.-C. Corvol et al., “Longitudinal analysis of impulse control disorders in
Parkinson disease,” Neurology, vol. 91, no. 3, pp. e189–e201, Jul. 2018.
[6] K. M. Smith, S. X. Xie, and D. Weintraub, “Incident impulse control disorder
symptoms and dopamine transporter imaging in Parkinson disease,” J. Neurol.
Neurosurg. Psychiatry, vol. 87, no. 8, pp. 864–870, 2016.
[7] A. H. Erga, G. Alves, O. B. Tysnes, and K. F. Pedersen, “Evolution of
impulsive-compulsive behaviors and cognition in Parkinson’s disease,” J.
Neurol., vol. 267, no. 1, pp. 259–266, 2020.
[8] P. Parra-Díaz et al., “Does the country make a difference in impulse control
disorders? A systematic review,” Movement Disord. Clin. Pract., vol. 8, no. 1,
pp. 25–32, 2021.
[9] A. L. Phu et al., “Effect of impulse control disorders on disability and quality
of life in Parkinson’s disease patients,” J. Clin. Neurosci., vol. 21, no. 1, pp.
63–66, 2014.
50. 42|Page
[10] I. Leroi, V. Harbishettar, M. Andrews, K. McDonald, E. J. Byrne, and A.
Burns, “Carer burden in apathy and impulse control disorders in Parkinson’s
disease,” Int. J. Geriatr. Psychiatry, vol. 27, no. 2, pp. 160–166, 2012.
[11] Yokoe, M., Okuno, R., Hamasaki, T., Kurachi, Y., Akazawa, K. & Sakoda, S. (2009),
‘Opening velocity, a novel parameter, for finger tapping test in patients with
Parkinson’s disease’, Parkinsonism & Related Disorders 15(6), 440–444
[12] Xie, F., Song, A. & Ciesielski, V. (2012), Event detection in time series by genetic
programming, in ‘Evolutionary Computation (CEC), 2012 IEEE Congress on’, IEEE,
pp. 1–8.
[13] Xing, Z., Pei, J. & Keogh, E. (2010), ‘A brief survey on sequence classification’,
ACM SIGKDD Explorations Newsletter 12(1), 40–48.
[14] Verplancke, T., Van Looy, S., Steurbaut, K., Benoit, D., De Turck, F., De Moor, G. &
Decruyenaere, J. (2010), ‘A novel time series analysis approach for prediction of
dialysis in critically ill patients using echo-state networks’, BMC medical informatics
and decision making 10(1), 4.
[15] Verstraeten, D., Schrauwen, B., Stroobandt, D. & Van Campenhout, J. (2005),
‘Isolated word recognition with the liquid state machine: a case study’, Information
Processing Letters 95(6), 521–528.
[16] Website of the Parkinson’s Disease Society (2013), Available at
http://www.parkinsons.org.uk. Widrow, B., Hoff, M. E. et al. (1960), ‘Adaptive
switching circuits.’
[17] L. Parisi, N. RaviChandran, and M. L. Manaog, “Feature-driven machine learning to
improve early diagnosis of parKinson’s disease,” Expert Syst. Appl., vol. 110, pp.
182– 190, 2018.
[18] R. Das, “A comparison of multiple classification methods for diagnosis of Parkinson
disease,” Expert Syst. Appl., vol. 37, no. 2, pp. 1568–1572, 2010.
[19] I. Maglogiannis, K. Karpouzis, M. Wallace, and J. Soldatos, Emerging Artificial
Intelligence Applications In Computer Engineering. IOS Press.
[20] G. Orrù, W. Pettersson-Yeo, A. F. Marquand, G. Sartori, and A. Mechelli, “Using
Support Vector Machine to identify imaging biomarkers of neurological and
psychiatric disease: A critical review,” Neurosci. Biobehav. Rev., vol. 36, no. 4, pp.
1140–1152, 2012.
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"Poster Session : POSTER SESSION",
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Publication
Hengyi Rao, Eugenia Mamikonyan, John A.
Detre, Andrew D. Siderowf, Matthew B. Stern,
Marc N. Potenza, Daniel Weintraub.
"Decreased ventral striatal activity with
impulse control disorders in Parkinson's
disease", Movement Disorders, 2010
Publication