This study introduces a hybrid deep learning model integrating Long Short-Term Memory (LSTM) networks with Particle Swarm Optimization (PSO) and Grey Wolf Optimization (GWO) to enhance predictions of COVID-19 spread in Indonesia, utilizing data from the Ministry of Health from 2020-2021. The proposed LSTM-PSO-GWO model improves predictive accuracy, crucial for effective decision-making regarding medical resources and policy responses amid the pandemic. This model addresses complexities in COVID-19 data, ensuring better performance over traditional forecasting methods.