This document provides guidance on diagnosing and treating Vibrio cholerae infection. It describes the clinical presentation ranging from asymptomatic to severe infection. Treatment involves oral rehydration with oral rehydration salts (ORS) for mild or moderate cases. Severe cases require intravenous fluids initially followed by a switch to ORS once hydrated. Antibiotics are recommended for severe cases. Zinc supplementation is also recommended for children with cholera to reduce severity and duration of illness.