BiG has two main objectives : - The first is to raise awareness of high-throughput sequencing technologies and the process of detecting genetic variations along a "bioinformatics pipeline", applied in a medical setting: in the vast world of genomics, this remains quite specialised! Bioinformatics can sometimes scare the uninitiated to the topic. This MOOC is an introduction to the main principles of the medical applications of genomics and it seemed important to us to teach it to the general public. - The second is to help create links between the various players in genomics: clinical geneticists, biologists, others medical specialists, bioinformaticians, students or those who have been practising it for years...