The document contains summaries of several data sets presented in tables and charts:
1) A student survey on preferred phone types shows 57% prefer Android and 43% prefer iPhone.
2) Production and scrap data for 12 foundry factories shows total production of 88,608 units and 1,368 units of scrap.
3) A chart shows median income increases with higher levels of education for both men and women.
4) Several Excel projects are presented using tables and charts to visualize data on topics like city populations, sports results, weather, expenses and company revenue.
Survey of Ukrainian Public Opinion: May, 2013Igor Tyshchenko
This document summarizes the results of a public opinion survey conducted in Ukraine from May 14-28, 2013. Over 1,200 Ukrainian residents were interviewed face-to-face. The survey found that most respondents believe the country is heading in the wrong direction and their financial situation has worsened over the past year. Unemployment, corruption, and low industry production were identified as the most important issues facing Ukraine. A plurality support Ukraine joining the European Union over a trade union with Russia.
Rihards Olups - Zabbix 3.0: Excited for new features?Zabbix
Rihards Olups has worked in the IT sector for more than 15 years, and in 2009 he joined Zabbix. He has had a chance to work with various systems, and most of that time has been spent with open source solutions. Exposure to Zabbix, one of the leading open source enterprise class monitoring solutions, was with the first public releases back in 2001, which has allowed to gain practical knowledge on the subject.
Zabbix Conference 2015
Daisuke Ikeda - Advanced SysOps by using HyClopsZabbix
This talk will demonstrate the capabilities of HyClops (open source), integrating it for Zabbix management
The presentation will overview the benefits of three components of HyClops - job monitoring module, proxy auto management module and external job management tool (JobShceduler), as well as automatic distribution control of Zabbix Proxy based on rules, discussing the path of future development and operation possibilities.
Zabbix Conference 2015
The document contains summaries of several data sets presented in tables and charts:
1) A student survey on preferred phone types shows 57% prefer Android and 43% prefer iPhone.
2) Production and scrap data for 12 foundry factories shows total production of 88,608 units and 1,368 units of scrap.
3) A chart shows median income increases with higher levels of education for both men and women.
4) Several Excel projects are presented using tables and charts to visualize data on topics like city populations, sports results, weather, expenses and company revenue.
Survey of Ukrainian Public Opinion: May, 2013Igor Tyshchenko
This document summarizes the results of a public opinion survey conducted in Ukraine from May 14-28, 2013. Over 1,200 Ukrainian residents were interviewed face-to-face. The survey found that most respondents believe the country is heading in the wrong direction and their financial situation has worsened over the past year. Unemployment, corruption, and low industry production were identified as the most important issues facing Ukraine. A plurality support Ukraine joining the European Union over a trade union with Russia.
Rihards Olups - Zabbix 3.0: Excited for new features?Zabbix
Rihards Olups has worked in the IT sector for more than 15 years, and in 2009 he joined Zabbix. He has had a chance to work with various systems, and most of that time has been spent with open source solutions. Exposure to Zabbix, one of the leading open source enterprise class monitoring solutions, was with the first public releases back in 2001, which has allowed to gain practical knowledge on the subject.
Zabbix Conference 2015
Daisuke Ikeda - Advanced SysOps by using HyClopsZabbix
This talk will demonstrate the capabilities of HyClops (open source), integrating it for Zabbix management
The presentation will overview the benefits of three components of HyClops - job monitoring module, proxy auto management module and external job management tool (JobShceduler), as well as automatic distribution control of Zabbix Proxy based on rules, discussing the path of future development and operation possibilities.
Zabbix Conference 2015
Kazuhiko Inaba - Ahiruyaki Monitored by Zabbix in JapanZabbix
This document discusses monitoring the term "Ahiruyaki" on Twitter using Zabbix. "Ahiruyaki" is a Japanese word that means burned duck and searching for it on Twitter returns duck pictures and jokes. Zabbix counts the number of times the term is mentioned daily and displays the data as a graph. It also monitors the term "Ahiruyaki" 24 hours a day from around the world. Upcoming events in Japan related to Zabbix and open source are mentioned.
Florian Koch - Monitoring CoreOS with ZabbixZabbix
This document discusses monitoring CoreOS using containers with Zabbix. It describes building a minimal container for the Zabbix agent using rkt that is only 600KB in size. Challenges discussed include managing the agent configuration inside the container, logging limitations due to kernel namespaces, and some checks not currently working. The document concludes by thanking the audience and providing sources on GitHub for more information.
Method validation for drug substances and drug product _remodified_2014Ramalingam Badmanaban
Method validation is the process of proving that an analytical method is acceptable for its intended purposes.
METHOD VALIDATION = ERROR ASSESSMENT
Method validation is the process of demonstrating that analytical procedures are suitable for their intended use and that they support the identity, strength, quality, purity and potency of the drug substances and drug products
Validation: Prior ConsiderationsSuitability of Instrument Status of Qualification and Calibration Suitability of Materials Status of Reference Standards, Reagents, Placebo Lots Suitability of Analyst Status of Training and Qualification Records Suitability of Documentation Written and approved standard test procedure and proper approved protocol with pre-established acceptance criteria
Compendial vs. Non-compendial Methods
Compendial methods-Verification
Regulatory analytical procedure in USP/NF
Non- compendial methods-Validation
Alternative analytical procedure proposed by the applicant for use instead of the regulatory analytical procedure
Chromatographic Methods
Demonstrate Resolution
Impurities/Degradants Available
Spike with impurities/degradants
Show resolution and a lack of interference
Impurities/Degradants Not Available
Stress SamplesFor assay, Stressed and Unstressed Samples should be compared.
Ability of an analytical method to measure the analyte free from interference due to other components.
Selectivity describes the ability of an analytical method to differentiate various substances in a sample
Original term used in USP
Also Preferred by IUPAC and AOAC
Also used to characterize chromatographic columns
Degree of Bias (Used in USP)
The difference in assay results between the two groups
the sample containing added impurities, degradation products, related chemical compounds, placebo ingredients
Selectivity: For impurity test, impurity profiles should be compared.
Temperature (50-60℃)
Humidity (70-80%)
Acid Hydrolysis (0.1 N HCl)
Base Hydrolysis (0.1 N NaOH)
Oxidation (3-30%)
Light (UV/Vis/Fl)
Intent is to create 10 to 30 % Degradation
Change in the analytical procedure, drug substance, drug product, the changes, may necessitate revalidation of the analytical procedures.
“The degree of revalidation depends on the nature of the change.”
“FDA intends to provide guidance in the future on post-approval changes in analytical procedures.”
By Visual Inspection of plot of signals vs. analyte concentration
By Appropriate statistical methods
Linear Regression (y = mx + b)
Correlation Coefficient, y-intercept (b), slope (m)
Acceptance criteria: Linear regression r2 > 0.999
Requires a minimum of 6 concentration levels
Normally derived from Linearity studies.
Established by confirming that the method provides acceptable degree of linearity, accuracy, and precision.
Specific range dependent upon intended application of the procedure.
Zabbix Smart problem detection - FISL 2015 workshopZabbix
Data collection
How often execute checks?
How to detect problems in this data flow?
Triggers
How to get rid of false positives?"
Examples
How to react on problems?
As always the conference was opened with a speech by Alexei Vladishev, the creator of Zabbix, glancing over the accomplishments Zabbix made during the past year, mostly focusing on the features and improvements that await us all in the Zabbix 3.0 release.
Zabbix Conference 2015
Introduction to Zabbix - Company, Product, Services and Use CasesZabbix
About Zabbix Software:
Zabbix is an enterprise-class open source distributed monitoring solution designed to monitor and track performance and availability of network servers, devices, services and other IT resources.
Zabbix is an all-in-one monitoring solution that allows users to collect, store, manage and analyze information received from IT infrastructure, as well as display on-screen, and alert by e-mail, SMS or Jabber when thresholds are reached.
Zabbix allows administrators to recognize server and device problems within a short period of time and therefore reduces the system downtime and risk of system failure. The monitoring solution is being actively used by SMBs and large enterprises across all industries and almost in every country of the world.
The document is a form for collecting information from teachers to send them promotional materials from the Anaya publishing group. It requests contact information, the schools and subjects they teach, which Anaya books they use, and information about their children.