Immunopharmacology

IMMUNOPHARMACOLOGY Ma. Janetth B. Serrano, M.D., DPBA

IMMUNOPHARMACOLOGY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY

IMMUNOPHARMACOLOGY 0psonized bacteria Macrophage APC T lymphocyte IL-2 IL-2 IFN-  Activated Macrophage Activated NK cells Activated Cytotoxic T cell CELL-MEDIATED IMMUNITY B lymphocyte IL-4,IL-5 TH 1 TH 2 Memory B Cells ,[object Object],[object Object],[object Object],HUMORAL IMMUNITY IFN-  TNF-  IFN- 

[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Immunosuppressants IMMUNOPHARMACOLOGY

Corticosteroids ,[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY Corticosteroids

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY Corticosteroids

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY Cyclosporin

Tacrolimus ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY

[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY Sirolimus (rapamycin)

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY Interferons

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY TNF- α binding drugs

[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY Mycophenolate Mofetil

[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY 15-Deoxyspergualin

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY Thalidomide

[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY Glatiramer

[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY CYTOTOXIC Agents:

[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY Azathioprine

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY Azathioprine

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY Leflunomide

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY Cyclophosphamide

Antibodies as Immunosuppressive Agents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY

[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY MONOCLONAL ANTIBODIES :

[object Object],[object Object],IMMUNOPHARMACOLOGY Muromonab-CD3

[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY

IMMUNOMODULATORS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

IMMUNOMODULATORS ,[object Object],Melanoma and Prostate cancer GM-CSF (+) effects in response to Hep B vaccine Interferons & IL-2 Malignant melanoma Soft tissue sarcoma of extremities TNF-alpha Metastatic renal cell CA Malignant melanoma Interleukin-2 Chronic granulomatous disease Interferon-gamma Relapsing type multiple sclerosis Interferon-beta

IMMUNOPHARMACOLOGY IMMUNOMODULATORS IMMUNOPHARMACOLOGY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

IMMUNOPHARMACOLOGY IMMUNOMODULATORS IMMUNOPHARMACOLOGY ,[object Object],[object Object],[object Object]

IMMUNOPHARMACOLOGY IMMUNOMODULATORS IMMUNOPHARMACOLOGY ,[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],“ The winds and waves are always on the side of the ablest navigator”

QUIZ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Immunopharmacology

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Immunopharmacology