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Neoplasia 4…. By shin n Kavita Picsfrm David Santos
AMYLOID DEPOSITS  DISEASE : AMYLOID , THYROID
Disease : Basal cell CA Characteristic appearance : Picket fence appearance Cells at pointer : Palisade of Basal cells
Epidermis that invaded  the dermis.. Squamous cells arranged into lobules Disease : Squamous cell CA Keratinization in the centers .. Known as keratin pearls
Landmark : normal alveoli Disease : tumor emboli, lungShows hematogenous spread.. The malignant cells will be found w/I the BV. Blood vessel Malignant cells  occluding the BV
Hematogenous spread  in Liver - Gross
Hair follicle Sebaceous gland Dermoid cyst , ovaryThere’s ectodermal differentiation due to presence of totipotential cell thus presenting with sebaceous gland, hair follicles, etc.See stuff that are not suppose to be seen in ovary!
Hair, teeth and sebaceous fluid seen in ovary
Papillary CA, thyroid Lymphoidspread Psammoma’s body Normal  thyroid follicle The thyroid follicles  are surrounded by malignant cells  … they are arranged into papillary  pattern.
Papillary CA, thyroid Lymphoidspread Orphan Annie nuclei appearance under HPO
Thyroid follicle Infiltration of Leukocytes Appears like Lymph node But actually , it’s a thyroid gland with autoimmune disease known as Hashimoto’s thyroiditis
Thyroid hyperplasia Grave’s Disease
Invasive Ductal carcinoma Ducts invading the stroma so there is reduced amount of stroma.. This is due to abnormality of ductal lining cell..
Rectal Adenocarcinoma Pleomorphism of cell and nucleus Elongated duct Hyperchromatic nucleus
Hydatidiform mole  (partial mole) Chorionic villi with hydropic degeneration
Hydatidiform mole – Gross… Appears like fish egg… WTF??? Does it???
Good Luck!!!!! Thnk u!!!!!!!!!!!!

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