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Native Oyster Disease Resistance Characterization
1. Characterizing disease
resistance in native oysters
that have experienced
disease pressure
Steven Roberts, Roxanna Smolowitz, Rick Karney
Northeastern Regional Aquaculture Center
23. Apoptosis – BCL-X
• Resistant oyster strains could downregulate
apoptosis suppression
• Allowing for increased apoptosis
• Decreasing number of cells available for
Perkinsus proliferation
27. Summary
• Offspring of survivors of heavy disease
pressure are more tolerant to disease
• Mechanisms involved in host responses to
P. marinus include proteases, apoptosis, and
molecule signaling
• Careful selection of broodstock (potentially
aided by markers) can benefit aquaculture
and conservation efforts
28. Future
• Increased analysis on current data set
• Analyze gene expression patterns in
different locations under different
diseased pressure
• Application of markers
• Could assignment be made via gene expression?
