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Goldman Stanley
Confidential Draft
Project Jaguar
Presentation to the Board of Directors
August 17, 2017
Goldman Stanley
Executive Summary
 Over the past year, Jaguar’s share price has barely changed, falling by ~33% (~$50) and then rising by ~50% (~$50) to
its current level of $147.40 (there has also been little net change over the past ~3 years)
 At its current levels, Jaguar is undervalued relative to Comparable Public Companies and on an intrinsic, cash-flow
basis; Precedent Transactions and Premiums also imply a much higher share price
 Jaguar’s promising portfolio, pricing power, and market position could make it an attractive acquisition candidate and
allow it to achieve a significantly higher valuation in a deal
 Such a strategy would allow Jaguar to maximize shareholder value, expand its geographic reach and distribution
channels, and acquire more resources for future research & development and M&A activity
 Given Jaguar’s unique attributes, we believe a purchase premium between 20% and 35%, implying share prices
ranging from approximately $175 to $200, is possible
 We recommend a highly targeted process focused on the most likely (“Tier 1”) potential partners, along with an
outreach to Tier 2 potential partners while discussions with Tier 1 partners are ongoing
2
Goldman Stanley
Summary of Jaguar Valuation
#1
Jaguar appears to be undervalued by 20-35%, depending on the methodology
and selected year
Implied Valuation
#2
Despite significantly higher revenue growth, EBITDA growth, and EBITDA
margins, Jaguar trades at a discount to the median EV / Revenue, EV /
EBITDA, and P / E multiples of its peer companies
Comparable Public
Companies
#3
Management forecasts indicate that Jaguar is moderately undervalued;
consensus figures produce the opposite result, but all analyses exclude the
value of potential synergies in an M&A deal
Discounted Cash Flow
(DCF) Analysis
#4
LTM EV / EBITDA multiples indicate an implied share price of $240+;
Premiums indicate an implied value between $180 and $200 per share
Precedent Transactions
3
Goldman Stanley
Operational Assumptions for Jaguar
4
Xyrem Peak Sales
Erwinaze Peak Sales
Defitelio Peak Sales
Vyxeos and JZP-110 Sales
Terminal Value
Implied Share Price
Management Forecast
 $3.8B in FY 22
Operating Margins
WACC
 $0.3B in FY 26
 $0.6B in FY 26
 $1.6B total in FY 26
 2.5% Terminal Growth Rate
 ~$157
 40% declining to 25-30%
 10.0% declining to 7.5%
Consensus Forecast
 $3.1B in FY 21
 $0.3B in FY 26
 $0.5B in FY 26
 $1.1B total in FY 26
 2.0% Terminal Growth Rate
 ~$113
 40% declining to 25-30%
 10.0% declining to 7.5%
Goldman Stanley
Management Case – Financial Projections
5
($ USD in Millions)
Goldman Stanley
Revenue Projections: Management vs. Consensus
6
($ USD in Billions)
Goldman Stanley
EBITDA Projections: Management vs. Consensus
7
($ USD in Billions)
Goldman Stanley
Valuation Summary – Management Case
 All market data as of August 16, 2017
 Given that Jaguar’s revenue growth, EBITDA growth, and EBITDA margins exceed those of its peer companies, we
believe that the 75th percentile multiples are the most applicable ones here
8
($ USD in Dollars as Stated)
Goldman Stanley
Jaguar Comparable Public Companies
Specialty Pharmaceutical Companies That Sell Primarily Branded Drugs, with LTM Revenue Between $500 Million and $5 Billion
9
(1) Financial data as of August 16, 2017.
($ USD in Billions)
Comparable Public Companies – Revenue, CY 2017E – CY 2018E(1)
Goldman Stanley
Jaguar Comparable Public Companies
Specialty Pharmaceutical Companies That Sell Primarily Branded Drugs, with LTM Revenue Between $500 Million and $5 Billion
10
(1) Financial data as of August 16, 2017.
($ USD in Billions)
Comparable Public Companies – EBITDA, CY 2017E – CY 2018E(1)
Goldman Stanley
Jaguar Comparable Public Companies
Specialty Pharmaceutical Companies That Sell Primarily Branded Drugs, with LTM Revenue Between $500 Million and $5 Billion
Comparable Public Companies – Growth and Valuation Multiples, CY 2017E – CY 2018E(1)
11
(1) Financial data as of August 16, 2017.
Goldman Stanley
Jaguar Precedent Transactions
U.S. and Canadian Pharmaceutical Sellers with $500 Million – $5 Billion in LTM Revenue, Aug. 16, 2012 – Aug. 16, 2017
12
($ USD in Millions)
Goldman Stanley
Jaguar DCF Analysis – Free Cash Flow Projections
13
($ USD in Millions)
Goldman Stanley
Jaguar DCF Analysis – Sensitivities
14
($ USD in Dollars as Stated)
 Output from the sensitivities below is based on the Management forecasts for Jaguar
 Range of Discount Rates is based on a 10.13% median WACC of comparable public companies and a 9.76% median
WACC with Jaguar’s current capital structure; Terminal Multiples and Growth Rates are linked to comparables
Goldman Stanley
Summary Profile of Equity Shareholders
Commentary:
 Gross Common Share Count: 58,739,693(1)
 Major institutional investors represent
approximately 97% of share ownership
 Largest institutional shareholders include:
 Putnam: 8,304,110 (14.1%)
 Fidelity: 8,290,410 (14.1%)
 Vanguard: 4,677,223 (8.0%)
 BlackRock: 3,110,681 (5.3%)
 Insiders own 2-3% of shares outstanding:
 Seamus Mulligan (Director): 1,048,008
(1.8%)
 Bruce Cozadd (CEO): 226,199 (0.4%)
 Given the lack of activist investors and the
high percentage of shares held by
traditional investment managers, the
chances of a challenge to a potential deal
are low
15
Source: Company proxy statements, investor filings, and Capital IQ.
(1) As of June 30, 2017 10-Q filing.
Investment
Managers:
81%
Hedge Funds:
12%
Individuals /
Insiders:
2%
Banks / Investment
Banks:
2%
Other:
3%
Goldman Stanley
Valuation Conclusions
The company’s margins and growth rates exceed the median figures of its
peer companies, indicating that it should be valued in-line with the 75th
percentile multiples
#1
This price represents a 35%+ premium to Jaguar’s current share price; greater
upside might be possible with a highly complementary partner
#2
Implied value is between $110 and $160 / share, but these projections do not
include possible synergies in an M&A deal and, as such, they likely undervalue
Jaguar
#3
Premiums Paid indicate a median implied share price of $180 – $200, with a
75th percentile implied share price in the $200 – $220 range
#4
“75th Percentile”
Valuation is Justified
Goal: $200 / Share
Discounted Cash Flow
(DCF) Analysis
Premiums Paid
Analysis
16
Goldman Stanley
Potential Strategic Partners
 Size, ability to pay, product/pipeline, and strategic fit should all be considered
 At $200 / share, Jaguar would be worth an Enterprise Value of nearly $15 billion; therefore, potential partners should be
able to drawn on this much Cash and Debt to fund the deal
 Both branded and generics companies should be considered, in light of recent M&A activity
Tier 1 Potential Partners Tier 2 Potential Partners
Market Cap:  Significantly larger than Jaguar  Closer to Jaguar’s size
Ability to Pay:  Capable of paying at least $10-15
billion in Cash and Debt
 May have to issue Stock to fund
the full purchase price
Strategic Fit:  Solid product and pipeline fit  Solid product and pipeline fit
17
Goldman Stanley
Potential Strategic Partners
Tier 1 Potential Partners
Tier 2 Potential Partners
18
Goldman Stanley
Key Recommendations
 We recommend engaging in targeted discussions with the Tier 1 candidates and assessing their receptiveness to M&A
discussions
 At the same time, Goldman Stanley will reach out to Tier 2 candidates and introduce Jaguar as a potential partner
 M&A process with Tier 1 candidates will take significantly longer due to the size of the companies, so we recommend
conducting both processes simultaneously
 Depending on the responses from Tier 1 and Tier 2 candidates, Goldman Stanley and Jaguar may do additional
research to determine other potential partners and then approach them
Targeted Sell-Side M&A Broad Sell-Side M&A
< 5 potential partners 10 – 100 potential partners
6 – 12 months Time required is highly variable
Close-ended Iterative process
Higher success probability Lower success probability
19
Goldman Stanley
Process Recommendations
 Combination of targeted discussions plus
broader search conducted in background
maximizes success probability and
minimizes disruption to Jaguar
 Additional parties contacted depend on
responsiveness of Tier 1 and Tier 2
partners
 Interested parties would sign NDAs and
then proceed into due diligence and
valuation discussions with Jaguar
Broad
Marketing
RECOMMENDED
Specialized
Negotiations With
One Party
Highly Targeted
Process
Broad M&A
Process
Targeted
Discussions +
Broader Search
20

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  • 1. Goldman Stanley Confidential Draft Project Jaguar Presentation to the Board of Directors August 17, 2017
  • 2. Goldman Stanley Executive Summary  Over the past year, Jaguar’s share price has barely changed, falling by ~33% (~$50) and then rising by ~50% (~$50) to its current level of $147.40 (there has also been little net change over the past ~3 years)  At its current levels, Jaguar is undervalued relative to Comparable Public Companies and on an intrinsic, cash-flow basis; Precedent Transactions and Premiums also imply a much higher share price  Jaguar’s promising portfolio, pricing power, and market position could make it an attractive acquisition candidate and allow it to achieve a significantly higher valuation in a deal  Such a strategy would allow Jaguar to maximize shareholder value, expand its geographic reach and distribution channels, and acquire more resources for future research & development and M&A activity  Given Jaguar’s unique attributes, we believe a purchase premium between 20% and 35%, implying share prices ranging from approximately $175 to $200, is possible  We recommend a highly targeted process focused on the most likely (“Tier 1”) potential partners, along with an outreach to Tier 2 potential partners while discussions with Tier 1 partners are ongoing 2
  • 3. Goldman Stanley Summary of Jaguar Valuation #1 Jaguar appears to be undervalued by 20-35%, depending on the methodology and selected year Implied Valuation #2 Despite significantly higher revenue growth, EBITDA growth, and EBITDA margins, Jaguar trades at a discount to the median EV / Revenue, EV / EBITDA, and P / E multiples of its peer companies Comparable Public Companies #3 Management forecasts indicate that Jaguar is moderately undervalued; consensus figures produce the opposite result, but all analyses exclude the value of potential synergies in an M&A deal Discounted Cash Flow (DCF) Analysis #4 LTM EV / EBITDA multiples indicate an implied share price of $240+; Premiums indicate an implied value between $180 and $200 per share Precedent Transactions 3
  • 4. Goldman Stanley Operational Assumptions for Jaguar 4 Xyrem Peak Sales Erwinaze Peak Sales Defitelio Peak Sales Vyxeos and JZP-110 Sales Terminal Value Implied Share Price Management Forecast  $3.8B in FY 22 Operating Margins WACC  $0.3B in FY 26  $0.6B in FY 26  $1.6B total in FY 26  2.5% Terminal Growth Rate  ~$157  40% declining to 25-30%  10.0% declining to 7.5% Consensus Forecast  $3.1B in FY 21  $0.3B in FY 26  $0.5B in FY 26  $1.1B total in FY 26  2.0% Terminal Growth Rate  ~$113  40% declining to 25-30%  10.0% declining to 7.5%
  • 5. Goldman Stanley Management Case – Financial Projections 5 ($ USD in Millions)
  • 6. Goldman Stanley Revenue Projections: Management vs. Consensus 6 ($ USD in Billions)
  • 7. Goldman Stanley EBITDA Projections: Management vs. Consensus 7 ($ USD in Billions)
  • 8. Goldman Stanley Valuation Summary – Management Case  All market data as of August 16, 2017  Given that Jaguar’s revenue growth, EBITDA growth, and EBITDA margins exceed those of its peer companies, we believe that the 75th percentile multiples are the most applicable ones here 8 ($ USD in Dollars as Stated)
  • 9. Goldman Stanley Jaguar Comparable Public Companies Specialty Pharmaceutical Companies That Sell Primarily Branded Drugs, with LTM Revenue Between $500 Million and $5 Billion 9 (1) Financial data as of August 16, 2017. ($ USD in Billions) Comparable Public Companies – Revenue, CY 2017E – CY 2018E(1)
  • 10. Goldman Stanley Jaguar Comparable Public Companies Specialty Pharmaceutical Companies That Sell Primarily Branded Drugs, with LTM Revenue Between $500 Million and $5 Billion 10 (1) Financial data as of August 16, 2017. ($ USD in Billions) Comparable Public Companies – EBITDA, CY 2017E – CY 2018E(1)
  • 11. Goldman Stanley Jaguar Comparable Public Companies Specialty Pharmaceutical Companies That Sell Primarily Branded Drugs, with LTM Revenue Between $500 Million and $5 Billion Comparable Public Companies – Growth and Valuation Multiples, CY 2017E – CY 2018E(1) 11 (1) Financial data as of August 16, 2017.
  • 12. Goldman Stanley Jaguar Precedent Transactions U.S. and Canadian Pharmaceutical Sellers with $500 Million – $5 Billion in LTM Revenue, Aug. 16, 2012 – Aug. 16, 2017 12 ($ USD in Millions)
  • 13. Goldman Stanley Jaguar DCF Analysis – Free Cash Flow Projections 13 ($ USD in Millions)
  • 14. Goldman Stanley Jaguar DCF Analysis – Sensitivities 14 ($ USD in Dollars as Stated)  Output from the sensitivities below is based on the Management forecasts for Jaguar  Range of Discount Rates is based on a 10.13% median WACC of comparable public companies and a 9.76% median WACC with Jaguar’s current capital structure; Terminal Multiples and Growth Rates are linked to comparables
  • 15. Goldman Stanley Summary Profile of Equity Shareholders Commentary:  Gross Common Share Count: 58,739,693(1)  Major institutional investors represent approximately 97% of share ownership  Largest institutional shareholders include:  Putnam: 8,304,110 (14.1%)  Fidelity: 8,290,410 (14.1%)  Vanguard: 4,677,223 (8.0%)  BlackRock: 3,110,681 (5.3%)  Insiders own 2-3% of shares outstanding:  Seamus Mulligan (Director): 1,048,008 (1.8%)  Bruce Cozadd (CEO): 226,199 (0.4%)  Given the lack of activist investors and the high percentage of shares held by traditional investment managers, the chances of a challenge to a potential deal are low 15 Source: Company proxy statements, investor filings, and Capital IQ. (1) As of June 30, 2017 10-Q filing. Investment Managers: 81% Hedge Funds: 12% Individuals / Insiders: 2% Banks / Investment Banks: 2% Other: 3%
  • 16. Goldman Stanley Valuation Conclusions The company’s margins and growth rates exceed the median figures of its peer companies, indicating that it should be valued in-line with the 75th percentile multiples #1 This price represents a 35%+ premium to Jaguar’s current share price; greater upside might be possible with a highly complementary partner #2 Implied value is between $110 and $160 / share, but these projections do not include possible synergies in an M&A deal and, as such, they likely undervalue Jaguar #3 Premiums Paid indicate a median implied share price of $180 – $200, with a 75th percentile implied share price in the $200 – $220 range #4 “75th Percentile” Valuation is Justified Goal: $200 / Share Discounted Cash Flow (DCF) Analysis Premiums Paid Analysis 16
  • 17. Goldman Stanley Potential Strategic Partners  Size, ability to pay, product/pipeline, and strategic fit should all be considered  At $200 / share, Jaguar would be worth an Enterprise Value of nearly $15 billion; therefore, potential partners should be able to drawn on this much Cash and Debt to fund the deal  Both branded and generics companies should be considered, in light of recent M&A activity Tier 1 Potential Partners Tier 2 Potential Partners Market Cap:  Significantly larger than Jaguar  Closer to Jaguar’s size Ability to Pay:  Capable of paying at least $10-15 billion in Cash and Debt  May have to issue Stock to fund the full purchase price Strategic Fit:  Solid product and pipeline fit  Solid product and pipeline fit 17
  • 18. Goldman Stanley Potential Strategic Partners Tier 1 Potential Partners Tier 2 Potential Partners 18
  • 19. Goldman Stanley Key Recommendations  We recommend engaging in targeted discussions with the Tier 1 candidates and assessing their receptiveness to M&A discussions  At the same time, Goldman Stanley will reach out to Tier 2 candidates and introduce Jaguar as a potential partner  M&A process with Tier 1 candidates will take significantly longer due to the size of the companies, so we recommend conducting both processes simultaneously  Depending on the responses from Tier 1 and Tier 2 candidates, Goldman Stanley and Jaguar may do additional research to determine other potential partners and then approach them Targeted Sell-Side M&A Broad Sell-Side M&A < 5 potential partners 10 – 100 potential partners 6 – 12 months Time required is highly variable Close-ended Iterative process Higher success probability Lower success probability 19
  • 20. Goldman Stanley Process Recommendations  Combination of targeted discussions plus broader search conducted in background maximizes success probability and minimizes disruption to Jaguar  Additional parties contacted depend on responsiveness of Tier 1 and Tier 2 partners  Interested parties would sign NDAs and then proceed into due diligence and valuation discussions with Jaguar Broad Marketing RECOMMENDED Specialized Negotiations With One Party Highly Targeted Process Broad M&A Process Targeted Discussions + Broader Search 20