JMAR introduces BioSentry, a system for continuous real-time monitoring of biological contamination in purified water and WFI. BioSentry provides benefits such as reduced costs from preventing product loss and recalls due to contamination. It offers automated, low maintenance monitoring of water purification processes with total system flow of 100ml/min and inspection volume rate of 1 ml per minute. BioSentry provides real-time results without the need for consumables or reagents.

1. MICROBIOLOGICAL RESULTS
STILL WAITING?
Benefits:
Continuous monitoring detects
biological contamination of WFI or
purified water in real time
Significantly lowers costs by reducing
product loss and product recalls due
JMAR INTRODUCES to contamination
Monitors effectiveness of water
purification processes
• CONSTANT WATER QUALITY AWARENESS Automated system offeres low
mainenance and low cost of ownership
• REAL-TIME BIOBURDEN MEASUREMENT
Features:
• INCREASED PROCESS CONTROL Total sytem flow 100ml/min
• ONLINE MINUTE BY MINUTE ANALYSIS Inspection volume rate ~ 1 ml per
minute (1.4 liters per day)
• IMMEDIATE MEASURABLE ROI Requires no consumables or reagents
for detection
• LOW ENERGY CONSUMPTION (300 WATTS)
Automatic cleaning
WAITING FOR MICROBIOLOGICAL
KBERG CONSULTANTS TEST RESULTS FOR WFI AND
STEWART JASON KOHNBERG
PURIFIED WATER IS NOW
4234 MASSEY PRESERVE TRAIL
RALEIGH, NC 27616 USA A THING OF THE PAST
PHONE (910)232-0342
STEW@KBERG.INFO
WWW.KBERG.INFO

2. REAL-TIME RESULTS, REAL SAVINGS
Sample Business Senerio
YEAR
BioSentry’s real-time results equal real savings for
BENEFIT DRIVERS
0 1
pharmaceutical manufacturers. The real-time
Reduction in Lot rejections (assumes impovement by 1 bactch) $400,000
REAL-TIME RESULTS, REAL SAVINGS
Reduction in investigation cycle time from process excursions data provided by BioSentry has the potential to
(manpower and Lab resources) $50,000
Loss of productivity due to line down time
Returning Real-Time Results increase productivity, reduce nished product
(assumes 1 batch produced) $400,000
No longer does the pharmaceutical industry have release time, as well as lower lot rejection rates.
Reduction in cycle time during production line restart after
maintenance $50,000
to wait for microbiological test results for WFI and While BioSentry does not replace conventional
Loss of productivity during production line restart
(assumes 1 batch produced) $400,000
puri ed water. BioSentry not only reduces the wait methods of testing , its advanced monitoring
Reduction in rework, reprocessing, and repeat testing $30,000
Total Annual Benefits $1,330,000 for microbial contamination results, it eliminates it. technologies can reduce the number of overall
Implementation lter 60% With real-time, on-line capabilities conventional tests needed every year resulting in
Total Benefits Realized $798,000
BioSentry allows users to substantial consumable cost and labor savings for
Initial Investment 0 1
Initial investment (assume 3 unitis to support operstions) $120,000 $0 monitor the biological activity manufacture rs.
Implementation Costs (Quali cation and regulatory costs) $100,000 $0
Ongoing support costs $5,000
of a water source from
$0
BioSentry’ s compact, reagent free, and energy
Training costs $10,000 $5,000 anywhere in the world
Other costs $0 $0 e cient design saves on operating costs around
at any time of day.
Total Costs $230,000 $10,000
the clock. Its multiple purchase incentives,
ROI Measures
Cost of capital 12%
Whether you are across the comprehensive training, and dedicated support
Net present value $2,312,057 lab or across the globe, team make keep initial costs low and result in a
Return on investment 298%
BioSentry will alert you quick return of investment.
Payback (in years) 0.29
the moment contamination occurs.
If you would like to learn more about BioSentry, or
Returning Real Savings discuss exactly how BioSentry can save you
Pharmaceutical manufacturers are nally able to money, please contact us at (858)946-6800 or visit
integrate the power of state-of-the-art technology us on the web at www.jmar.com.
with long standing scienti c methods to assure
continuous water purity. JMAR’s BioSentry is the
only rapid microbiological method (RMM) of detec-
tion that o ers real-time, on-line, monitoring for
microorganisms in process water.
KBERG CONSULTANTS
(910)232-0342
www.kberg.info