• Epilepsy is a disorder of the brain characterized by an enduring
predisposition to generate seizures and by the neurologic, cognitive ,
psychological , and social consequences of this condition .
• The clinical diagnosis of epilepsy usually requires the occurrence of at least
one unprovoked epileptic seizure with either a second such seizure or
enough EEG and clinical information to convincingly demonstrate an
enduring predisposition to develop recurrence .
• For epidemiologic and commonly , for clinical purposes, epilepsy is
considered present when two or more unprovoked seizures occur in a time
frame of longer than 24 hrs.
Definition of an epilepsy
• an epilepsy syndrome is a cluster of features incorporating
typical seizure types, EEG, and imaging features that tend to
occur together, often with age-dependent features such as age
at onset and remission (where applicable), seizure triggers,
diurnal variation, sometimes prognosis, and distinctive
comorbidities such as intellectual and psychiatric dysfunction.
Scheffer IE, Berkovic S, Capovilla G, Connolly MB, French J, Guilhoto L, et al. ILAE classification of
the epilepsies: position paper of the ILAE Commission for Classification and Terminology. Epilepsia.
1/4th of patients has family history , chromosome15q14 ,
pathogenic variant inKCNQ2
Mild cognitive dysfunction and behavioral changes
• ILAE classification and definition of epilepsy syndromes with onset in
neonates and infants, DOI: 10.1111/epi.17239,
• Epileptic Syndromes in Childhood. A Practical Approach: Paulo Breno
Noronha Liberalesso1, DOI: 10.25060/residpediatr-2018.v8s1-10
Notes de l'éditeur
Most common type of focal epilepsy
1/4th of patients has family history , chromosome15q14 , pathogenic variant inKCNQ2
Motor symptoms involving face and no impairement of conciuousness