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Cephalosporins penems

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CLINICAL ASPECTS OF CEPHALOSPORIN AND PENEM GROUP OF ANTIBIOTICS
Beta lactam Antibiotics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cephalosporins ,[object Object],[object Object],[object Object],[object Object],[object Object]
Classification ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
SECOND GENERATION G+ve G-ve beta lactamase stability ++ ++ + + ORAL PARENTERAL Cefamandole C efaclor Cefotiam Cefuroxime axetil Ceforanide Cefprozil Cefonicid Cefuroxime Cefmetazole Cefacetrile Cefotiam Cefranide Loracarbef Cefoxitin * Cefotetan * * Cephamycins
THIRD GENERATION G+ve G-ve beta lactamase stability +/++ +++ ++ + ORAL PARENTERAL Cefsulodin Ceftiofur Ceforanide Cefotaxime Cefpodoxime proxetil Cefmenoxime Cefixime Ceftriaxone Ceftibuten Ceftizoxime Cefdinir Ceftazidime Cefmenoxime Cefovecin Cefditren pivoxil Cefoperazone Cefodizime Latamoxef (moxalactam)* Cefetamet * Cephamycins
FOURTH GENERATION G+ve G-ve beta lactamase stability ++/+++ ++++ + ++ + ORAL PARENTERAL Cefmetazole Cefepime Cefditoren Cefpirome Cefquinome
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],FIRST GENERATION
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pharmacokinetics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
CARBAPENEMS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CARBAPENEMS…contd ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Imipenem…contd ,[object Object],[object Object],[object Object],[object Object]
Meropenem ,[object Object],[object Object],[object Object],[object Object]

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Cephalosporins penems

  • 1. CLINICAL ASPECTS OF CEPHALOSPORIN AND PENEM GROUP OF ANTIBIOTICS
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  • 6. SECOND GENERATION G+ve G-ve beta lactamase stability ++ ++ + + ORAL PARENTERAL Cefamandole C efaclor Cefotiam Cefuroxime axetil Ceforanide Cefprozil Cefonicid Cefuroxime Cefmetazole Cefacetrile Cefotiam Cefranide Loracarbef Cefoxitin * Cefotetan * * Cephamycins
  • 7. THIRD GENERATION G+ve G-ve beta lactamase stability +/++ +++ ++ + ORAL PARENTERAL Cefsulodin Ceftiofur Ceforanide Cefotaxime Cefpodoxime proxetil Cefmenoxime Cefixime Ceftriaxone Ceftibuten Ceftizoxime Cefdinir Ceftazidime Cefmenoxime Cefovecin Cefditren pivoxil Cefoperazone Cefodizime Latamoxef (moxalactam)* Cefetamet * Cephamycins
  • 8. FOURTH GENERATION G+ve G-ve beta lactamase stability ++/+++ ++++ + ++ + ORAL PARENTERAL Cefmetazole Cefepime Cefditoren Cefpirome Cefquinome
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