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DIABETES TREATMENT  AND  PREVENTION LAVANYA.K ROLL NO.39
Goals of therapy ,[object Object],[object Object],[object Object],[object Object]
Healthcare Team ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment Goals INDEX GOAL ,[object Object],[object Object],[object Object],[object Object],<7 90-130 mg/dl <180 mg/dl Blood pressure <130/80 ,[object Object],[object Object],[object Object],[object Object],<100mg/dl >40mg/dl <150mg/dl
Diabetes education ,[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
EXERCISE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Assesment of long term glycemic control ,[object Object],[object Object],[object Object]
 
Treatment of type 1 Diabetes Preparation Onset (hr) Peak (hr) Eff.duration(hr) ,[object Object],[object Object],[object Object],[object Object],[object Object],<0.25 “ “ 0.5- 1.0 0.5- 1.5 “ “ 2-3 3-4 “ “ 4-6 ,[object Object],[object Object],<0.25 0.5-1.5 4-6 ,[object Object],[object Object],[object Object],[object Object],1-4 “ “ 6-10 Dual peak Dual peak 10-16 12-20 24
Insulin Combinations ,[object Object],[object Object],[object Object],[object Object],[object Object]
INSULIN REGIMENS
INSULIN PREPARATIONS ,[object Object],[object Object]
GUIDELINES FOR MIXING OF INSULIN ,[object Object],[object Object],[object Object],[object Object]
CALCULATION OF INSULIN DOSE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
METHODS OF INSULIN DELIVEY ,[object Object],[object Object],[object Object],[object Object],[object Object]
INSULIN SYRINGE
ROTATION SITES
INULIN PEN ,[object Object],[object Object],[object Object],[object Object],[object Object]
Insulin jet injectors ,[object Object],[object Object],[object Object]
 
BLOOD GLUCOSE MONITORING ,[object Object],[object Object],[object Object]
TREATMENT OF TYPE II DIABETES MANAGEMENT OF  TYPE II DIABETES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Treatment of type 2 diabetes mellitus Oral Biguanides Metformin Alpha glucosidase inhibitors Acarbose ,  meglitol DPP 4 inhibtors sitagliptin Insulin secretagogues sulfonyl ureas first generation chlorpropamide,tolbutamide second generation Glimepiride ,  glipizide non sulfonyl ureas  Repaglinide , nateglinide – Thiazolidinedidones roseglitazone,  pioglitazone
Parenteral Insulin GLP1 agonist exenatide Amylin agonist pramlintide
 
 
drugs advantages Disadvantages biguanides Weight loss Lactic acidosis,GI dysfunctions Alpha glucosidase inhibitor Reduce postprandial glycaemia Liver & GI dysfunctions DPP4 inhibitors No hypoglcaemia --- sulfonylureas Lowers fasting blood glucose Weight gain,hypoglyacemia Nonsulfonylureas thiazolidinediones Shorter onset of action Lowers postprandial glycaemia Lowera insulin requirements Hypoglycaemia CHF,weight gain ,fractures
Glycaemic management of type 2 diabetes mellitus patient with type 2 diabetes medical, nutrition therapy,increased physical  Activity and weight loss + metformin Reasses A1C Combination therapy metformin+second  agent Reasses A1C Combination therapy metformin+2 agents  metformin +insuln
[object Object],[object Object],[object Object],Treatment for diabetic nephropathy
[object Object]
TREATMENT FOR DIABETIC NEUROPATHY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
TREATMENT FOR GI DYSFUNCTION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
TREATMENT FOR GENITOURINARY DYSFUNCTION ,[object Object],[object Object],[object Object]
TREATMENT FOR CARDIOVASCULAR DYSFUNCTION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
New technologies in treatment of diabetes ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Thank you

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Treatment & Prevention 6

  • 1. DIABETES TREATMENT AND PREVENTION LAVANYA.K ROLL NO.39
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  • 27. Treatment of type 2 diabetes mellitus Oral Biguanides Metformin Alpha glucosidase inhibitors Acarbose , meglitol DPP 4 inhibtors sitagliptin Insulin secretagogues sulfonyl ureas first generation chlorpropamide,tolbutamide second generation Glimepiride , glipizide non sulfonyl ureas Repaglinide , nateglinide – Thiazolidinedidones roseglitazone, pioglitazone
  • 28. Parenteral Insulin GLP1 agonist exenatide Amylin agonist pramlintide
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  • 31. drugs advantages Disadvantages biguanides Weight loss Lactic acidosis,GI dysfunctions Alpha glucosidase inhibitor Reduce postprandial glycaemia Liver & GI dysfunctions DPP4 inhibitors No hypoglcaemia --- sulfonylureas Lowers fasting blood glucose Weight gain,hypoglyacemia Nonsulfonylureas thiazolidinediones Shorter onset of action Lowers postprandial glycaemia Lowera insulin requirements Hypoglycaemia CHF,weight gain ,fractures
  • 32. Glycaemic management of type 2 diabetes mellitus patient with type 2 diabetes medical, nutrition therapy,increased physical Activity and weight loss + metformin Reasses A1C Combination therapy metformin+second agent Reasses A1C Combination therapy metformin+2 agents metformin +insuln
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