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Prepared By: Dr. Tanjim Reza 
DA Student, CMCH 
ORGANISED BY 
Bangladesh Society of anaesthesiologist 
Chittagong branch
 It is a pharmacologically induced and reversible state of 
amnesia, analgesia, loss of responsiveness, loss of skeletal 
muscle reflexes or decreased stress response, or all 
simultaneously. 
 An alternative definition is a ‘’reversible lack of 
awareness’’ including a total lack of awareness of a part of 
the body such as spinal anesthetic. 
 The word Anaesthesia was coined by Oliver Wendell 
Holmes Sr. in 1846
Triad of Anaesthesia 
• Relive from painful surgery 
• Need of unconsciousness 
• Need of muscle relaxation
 An understanding of our past, guiding our future 
 The history of surgery follows the history of 
Anaesthesia 
 We are all part of it
 Pre- 1846 – The foundation of Anaesthesia 
 1848-1900 – Establishment of Anaesthesia 
 20th century – Consolidation and growth 
 21st century – The future
Drug Methods – 
• Alcohol 
• Opium 
• Hyoscine 
• Cannabis 
• Cocaine
Non Drug Methods: 
 Cold 
 Concussion 
 Carotid compression 
 Nerve compression 
 Hypnosis 
 Mesmeric Magnetism 
 Blood letting
Status of surgery: 
• Barber shop surgery 
Types of Surgery: 
• Amputation and dental extractions 
• No antisepsis 
• Appalling Mortality 
Indications:- 
• Unbearable pain 
• Crippling deformity 
• Imminent death
 1665 _ 1st IV injection opiate through a quill 
 Late 1700 – 
- Lots of new gases identified 
- Treatment of existing diseases rather than novel use
 Joseph Priestly – Produced N2O in 1772 
 Humphrey Davy – 1st Noted N2O’s analgesic properties 
in 1800
Contd. 
1834 – Colton Anesthetized 6 Indians by mistake 
1844 – Horace Wells had his tooth pulled under N2O 
1845 –Wells failed to demonstrate N2O at MGH
1540 – Synthesized and named sweet oil of vitriol by 
Valerius Cordus 
* Forbenius renamed it to Ether 
* 1744 – Methew Turner Published essay suggesting its 
inhalation in certain types of pain 
• Michael faraday Described narcotic effect of Ether 
• 1842 First used as a clinical anesthetic in USA 
• Clarke and Long used Ether for operations
Ether Dome
• On 16th October 1846 first public demonstration of 
Ether Anaesthesia took place in Boston 
• William T G Morton 
- Inventor and revealer of inhalation Anaesthesia: 
- Before whom, in all time, surgery was agony by whom 
pain in surgery was averted and annulled; since whom 
science has control of pain.
 Anesthetist: William Thomas 
Green Morton 
 Agent: Diethyl Ether 
 Patient: Gilbert Abbott 
 Operation: Excision of tumor 
under jaw 
 Surgeon: John Collins Warren 
 Comment: Gentleman this is 
no humbug
AnaesthesiaMemorial Boston 
Monument in Charlton Massachusetts
Henry Hill 
Hickman: 
- 1821 semi asphyxiation due to air 
starvation or by breathing CO2 gas 
* After unconsciousness was induced 
operated on them – 
# Amputation 
# Removal of ears 
# Skin Incisions and observed 
response to surgery 
# Evidence of Pain 
# Amount of bleeding to recovery
 1831 – Chloroform was synthesized 
 1847 – James Young Simpson used chloroform for 
obstetric Anaesthesia 
 1847 – John Snows Regulating inhaler 
 1848 – Honnoh Greeners – First Anesthetic death
Dr. John Snow used Chloroform as anesthetic in 1853 
Queen Victoria used it when she gave birth to her son Leopold, since it became 
mainstream
- Intubation and Airway advances 
- Anesthetic equipment 
- Monitoring 
- Drug Advance 
- Local Anaesthesia 
- Anaesthesia and intensive Care 
- Pain Management 
- Organization of Specialty
 1919 – Endotracheal 
intubation 
 1928 – Blind Nasal 
Intubation 
 1950 – PVC tube 
introduced 
 1980 – LMA introduced
 1908 – Rota Meter 
 1917 – Boyles Machine 
 1919 – Endotracheal Intubation 
 1938 – Artificial Respiration 
 1940 – Oxford vaporizer
 Blood pressure recorded at MGH 
 1946 –O2 analyzer 
 1949 –Nerve stimulator 
 1956-Blood gas monitoring 
 1960-ECG and Capnograph, CVP ,arterial monitoring.
 1911-balanced anaesthesia 
 1942-Curare 
 1951-Suxamethonium 
 1956-Halothane 
 1964-introduction of entonox 
 1980-Opioids-fentanyl/ 
PROPOFOL,vecuron 
ium/atracurium 
 1990- 
sevoflurane,desflurane,Rocur 
onium
 In the 1940s scientists discovered the active ingredient in 
South american Amazon Indian arrow poison;It’s Curare. 
 The only problem with using this stuff is that person was so 
relaxed that be can’t breathe or swallow –but he was fully 
awake .This opened the “age of Anaesthesia.”
 1860-Cocaine isolated 
 1884-Koller ;Topical Anaesthesia 
 1885-spinal analgesia by corning 
 1898-August bier –Spinal 
Anaesthesia 
 1901-Epidural Anaesthesia 
 1908-IVRA –Bier’s block 
 1921-Lumber epidural analgesia – 
pages 
 1943-Lignocaine 
 1963-Bupuvacaine August Bier
 1967-PCA 
 1990-Acute pain team, Multimodal analgesia, Epidural 
analgesia
 1932-Assosiation of anesthetist GB & I 
 1935-Diploma in Anaesthesia 
 1948-Faculty of anesthetist of RCS 
 1953-FRCA
 New and better drugs 
 New equipments 
 Increased demand for anaesthetic services 
 Questioning roles inside theatre 
 Stuffing and workload issues
 In 2000 BC , Sushratha used to perform plastic surgery 
of cut nose with use of opium,Indian hemp and wine 
to keep the patient sedated. 
 In the Buddhist Era ,in BC 247 ,laparotomy was 
described using alcohol to obtund pain. 
 In 1843 Esdale reported surgical operation under 
mesmeric anaesthesia in Hoogly Hospital In West 
Bengal. 
 Ether anaesthesia was used in India only six months its 
official demonostration on october 16,1846 in 
MGH,USA.
 For operative procedures,Local anaesthesia and 
regional blocks were in use and practiced by the 
Surgeons themselves at DMC. 
 General anaesthesia was used under supervision of the 
surgeons and used to be administered by the house 
surgeons of the respective departments.
 Dr.Beni Madhab Basak a house surgeon was mostly 
responsible to administer general anaesthesia till 
December ,1948. 
 Dr.S.M Mukhlesur Rahman ,MB was the first 
physiacian appointed as an Anaesthetist,DMCH. 
 Upto sixties most of the hospital have no recognized 
anaesthetist to deliver anaesthesia and sometimes it 
was given by nondoctors under the supervision of 
surgeon.
 The first post-graduate anaesthetist is Dr.k.A.S.M.A 
Quader ,DA (London). 
 1951 Dr.Abdul Quader ,MB,DA (London) has been in 
charge,Dep’t of Anaesthesia of the Medical College 
Hospital ,Dhaka.
 Infiltration analgesia,field blocks,regional blocks were 
popular amongst the surgeons in those days. 
 Procaine was the drug used for local analgesia. 
 Heavy Cinchocaine(Nupercaine)was in use for spinal 
analgesia. 
 Chloroform,ether and ethyl chloride were the volatile 
anaesthetics used for general anaesthesia.
Gradually,modern anaesthetic machines replaced in 
most centre’s and in all of the educational institutes. 
The first machine was the Boyle’s apparatus available 
since 1949 at DMCH.
 Ether continued to be in use in opendrop method and in Boyle’s 
Machines. 
 Halothane was introduced in late fifties,in course of time 
Halothane replaced other volatile agents. 
 Suxamethonium was introduced in early sixties. 
 Pancuronium Bromide was introduced in mid –eightes. 
 Atracurium was introduced in late eighties. 
 Vacuronium was introduced in early nineties. 
 Pipecuronium was introduced in late nineties. 
 Spinal anaesthesia was re –introduced and very popularly used in 
most of the hospitals. 
 Piped Medical gases & Vacuum was introduced in DMCH on 19th 
February 1985 and are extended in many hospitals.
 Anaesthesia service was recorded with a very short of 
trained manpower in Chittagong Medical college & 
Hospital in 1956. 
 Department extended in all govt.medical college 
hospitals or institutes,private medical college 
hospitals, 
 District hospitals and upto Upazila health complexes 
still with a a very short of trained manpower.
 Prof.S N Samad Chowdhury DA 
(London).FCPS.FFARCS who was the long time 
president of BSA and has great contribution for 
anaesthetic expansion in Bangladesh.
 In 1947 there is no recognized trained 
anaesthesiologist. 
 In 1948 two self trained and one in 1951 ,total three 
with one recognized . 
 1981 gradually increased interest in this field due to 
national demand with improved some dignity but still 
slow.
 DA : First two were Dr.Fakhrun Nissa and Dr.Dilip 
Kumar Das. 
 MCPS :First Bangladesh MCPS is Dr M Khalilur 
Rahman in 1976. 
 FCPS : The First fellow was Dr.Selim M Jahangir who 
was awarded fellowship in 1983. 
 MD : The first MD was Dr. Md.Abdul Hai ,Chairman 
of BSMMU .
 Bangladesh Society of Anaesthesiologists (BSA) was 
formed in 1974 with Pro.K.A.S.M. Quader and 
Dr.Md.Shafiqur Rasul as its President and Secretary 
respectively .
 Peri –operative anesthetic management . 
 Intensive Care 
 Pain clinic 
 Palliative care . 
 Intensive care unit was started in DMCH in September 
1985 with a six bed only.
 The First Journal of BSA was published in 1987 Dr.K.M 
Iqbal as its Editor.Two issues of Journals per year are 
published regularly.
 Epidural anaesthesia 
 Epidural analgesia with catheter 
 Caudal anaesthesia with additives 
 Supraclavicular Brachial plexus block 
 Interscalene Brachial plexus block 
 Superficial cervical plexus block 
 Femoral nerve block
 Now a days complicated surgical procedures like cardiac 
surgery ,neuro surgery,thoracic surgery,kidney transplant 
,pain management and intensive care patients have been 
possible due to improvement of Anaesthesiology. 
 Still we are lacking of some basic infrastructural problems 
like - 
 -proper placement and distribution of manpower. 
 -Availabilty of equipments, 
 -Standard monitors and Drugs at all levels of health 
care . 
 However we are very mutch hopefull awaiting a golden 
future.
Thank You

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History of Anaesthesia - Dr Tanjim Reza

  • 1. Prepared By: Dr. Tanjim Reza DA Student, CMCH ORGANISED BY Bangladesh Society of anaesthesiologist Chittagong branch
  • 2.  It is a pharmacologically induced and reversible state of amnesia, analgesia, loss of responsiveness, loss of skeletal muscle reflexes or decreased stress response, or all simultaneously.  An alternative definition is a ‘’reversible lack of awareness’’ including a total lack of awareness of a part of the body such as spinal anesthetic.  The word Anaesthesia was coined by Oliver Wendell Holmes Sr. in 1846
  • 3. Triad of Anaesthesia • Relive from painful surgery • Need of unconsciousness • Need of muscle relaxation
  • 4.  An understanding of our past, guiding our future  The history of surgery follows the history of Anaesthesia  We are all part of it
  • 5.  Pre- 1846 – The foundation of Anaesthesia  1848-1900 – Establishment of Anaesthesia  20th century – Consolidation and growth  21st century – The future
  • 6. Drug Methods – • Alcohol • Opium • Hyoscine • Cannabis • Cocaine
  • 7. Non Drug Methods:  Cold  Concussion  Carotid compression  Nerve compression  Hypnosis  Mesmeric Magnetism  Blood letting
  • 8. Status of surgery: • Barber shop surgery Types of Surgery: • Amputation and dental extractions • No antisepsis • Appalling Mortality Indications:- • Unbearable pain • Crippling deformity • Imminent death
  • 9.  1665 _ 1st IV injection opiate through a quill  Late 1700 – - Lots of new gases identified - Treatment of existing diseases rather than novel use
  • 10.  Joseph Priestly – Produced N2O in 1772  Humphrey Davy – 1st Noted N2O’s analgesic properties in 1800
  • 11. Contd. 1834 – Colton Anesthetized 6 Indians by mistake 1844 – Horace Wells had his tooth pulled under N2O 1845 –Wells failed to demonstrate N2O at MGH
  • 12. 1540 – Synthesized and named sweet oil of vitriol by Valerius Cordus * Forbenius renamed it to Ether * 1744 – Methew Turner Published essay suggesting its inhalation in certain types of pain • Michael faraday Described narcotic effect of Ether • 1842 First used as a clinical anesthetic in USA • Clarke and Long used Ether for operations
  • 13.
  • 15. • On 16th October 1846 first public demonstration of Ether Anaesthesia took place in Boston • William T G Morton - Inventor and revealer of inhalation Anaesthesia: - Before whom, in all time, surgery was agony by whom pain in surgery was averted and annulled; since whom science has control of pain.
  • 16.  Anesthetist: William Thomas Green Morton  Agent: Diethyl Ether  Patient: Gilbert Abbott  Operation: Excision of tumor under jaw  Surgeon: John Collins Warren  Comment: Gentleman this is no humbug
  • 17. AnaesthesiaMemorial Boston Monument in Charlton Massachusetts
  • 18. Henry Hill Hickman: - 1821 semi asphyxiation due to air starvation or by breathing CO2 gas * After unconsciousness was induced operated on them – # Amputation # Removal of ears # Skin Incisions and observed response to surgery # Evidence of Pain # Amount of bleeding to recovery
  • 19.  1831 – Chloroform was synthesized  1847 – James Young Simpson used chloroform for obstetric Anaesthesia  1847 – John Snows Regulating inhaler  1848 – Honnoh Greeners – First Anesthetic death
  • 20. Dr. John Snow used Chloroform as anesthetic in 1853 Queen Victoria used it when she gave birth to her son Leopold, since it became mainstream
  • 21. - Intubation and Airway advances - Anesthetic equipment - Monitoring - Drug Advance - Local Anaesthesia - Anaesthesia and intensive Care - Pain Management - Organization of Specialty
  • 22.  1919 – Endotracheal intubation  1928 – Blind Nasal Intubation  1950 – PVC tube introduced  1980 – LMA introduced
  • 23.  1908 – Rota Meter  1917 – Boyles Machine  1919 – Endotracheal Intubation  1938 – Artificial Respiration  1940 – Oxford vaporizer
  • 24.  Blood pressure recorded at MGH  1946 –O2 analyzer  1949 –Nerve stimulator  1956-Blood gas monitoring  1960-ECG and Capnograph, CVP ,arterial monitoring.
  • 25.  1911-balanced anaesthesia  1942-Curare  1951-Suxamethonium  1956-Halothane  1964-introduction of entonox  1980-Opioids-fentanyl/ PROPOFOL,vecuron ium/atracurium  1990- sevoflurane,desflurane,Rocur onium
  • 26.  In the 1940s scientists discovered the active ingredient in South american Amazon Indian arrow poison;It’s Curare.  The only problem with using this stuff is that person was so relaxed that be can’t breathe or swallow –but he was fully awake .This opened the “age of Anaesthesia.”
  • 27.  1860-Cocaine isolated  1884-Koller ;Topical Anaesthesia  1885-spinal analgesia by corning  1898-August bier –Spinal Anaesthesia  1901-Epidural Anaesthesia  1908-IVRA –Bier’s block  1921-Lumber epidural analgesia – pages  1943-Lignocaine  1963-Bupuvacaine August Bier
  • 28.  1967-PCA  1990-Acute pain team, Multimodal analgesia, Epidural analgesia
  • 29.  1932-Assosiation of anesthetist GB & I  1935-Diploma in Anaesthesia  1948-Faculty of anesthetist of RCS  1953-FRCA
  • 30.  New and better drugs  New equipments  Increased demand for anaesthetic services  Questioning roles inside theatre  Stuffing and workload issues
  • 31.  In 2000 BC , Sushratha used to perform plastic surgery of cut nose with use of opium,Indian hemp and wine to keep the patient sedated.  In the Buddhist Era ,in BC 247 ,laparotomy was described using alcohol to obtund pain.  In 1843 Esdale reported surgical operation under mesmeric anaesthesia in Hoogly Hospital In West Bengal.  Ether anaesthesia was used in India only six months its official demonostration on october 16,1846 in MGH,USA.
  • 32.  For operative procedures,Local anaesthesia and regional blocks were in use and practiced by the Surgeons themselves at DMC.  General anaesthesia was used under supervision of the surgeons and used to be administered by the house surgeons of the respective departments.
  • 33.  Dr.Beni Madhab Basak a house surgeon was mostly responsible to administer general anaesthesia till December ,1948.  Dr.S.M Mukhlesur Rahman ,MB was the first physiacian appointed as an Anaesthetist,DMCH.  Upto sixties most of the hospital have no recognized anaesthetist to deliver anaesthesia and sometimes it was given by nondoctors under the supervision of surgeon.
  • 34.  The first post-graduate anaesthetist is Dr.k.A.S.M.A Quader ,DA (London).  1951 Dr.Abdul Quader ,MB,DA (London) has been in charge,Dep’t of Anaesthesia of the Medical College Hospital ,Dhaka.
  • 35.  Infiltration analgesia,field blocks,regional blocks were popular amongst the surgeons in those days.  Procaine was the drug used for local analgesia.  Heavy Cinchocaine(Nupercaine)was in use for spinal analgesia.  Chloroform,ether and ethyl chloride were the volatile anaesthetics used for general anaesthesia.
  • 36. Gradually,modern anaesthetic machines replaced in most centre’s and in all of the educational institutes. The first machine was the Boyle’s apparatus available since 1949 at DMCH.
  • 37.  Ether continued to be in use in opendrop method and in Boyle’s Machines.  Halothane was introduced in late fifties,in course of time Halothane replaced other volatile agents.  Suxamethonium was introduced in early sixties.  Pancuronium Bromide was introduced in mid –eightes.  Atracurium was introduced in late eighties.  Vacuronium was introduced in early nineties.  Pipecuronium was introduced in late nineties.  Spinal anaesthesia was re –introduced and very popularly used in most of the hospitals.  Piped Medical gases & Vacuum was introduced in DMCH on 19th February 1985 and are extended in many hospitals.
  • 38.  Anaesthesia service was recorded with a very short of trained manpower in Chittagong Medical college & Hospital in 1956.  Department extended in all govt.medical college hospitals or institutes,private medical college hospitals,  District hospitals and upto Upazila health complexes still with a a very short of trained manpower.
  • 39.  Prof.S N Samad Chowdhury DA (London).FCPS.FFARCS who was the long time president of BSA and has great contribution for anaesthetic expansion in Bangladesh.
  • 40.  In 1947 there is no recognized trained anaesthesiologist.  In 1948 two self trained and one in 1951 ,total three with one recognized .  1981 gradually increased interest in this field due to national demand with improved some dignity but still slow.
  • 41.  DA : First two were Dr.Fakhrun Nissa and Dr.Dilip Kumar Das.  MCPS :First Bangladesh MCPS is Dr M Khalilur Rahman in 1976.  FCPS : The First fellow was Dr.Selim M Jahangir who was awarded fellowship in 1983.  MD : The first MD was Dr. Md.Abdul Hai ,Chairman of BSMMU .
  • 42.  Bangladesh Society of Anaesthesiologists (BSA) was formed in 1974 with Pro.K.A.S.M. Quader and Dr.Md.Shafiqur Rasul as its President and Secretary respectively .
  • 43.  Peri –operative anesthetic management .  Intensive Care  Pain clinic  Palliative care .  Intensive care unit was started in DMCH in September 1985 with a six bed only.
  • 44.  The First Journal of BSA was published in 1987 Dr.K.M Iqbal as its Editor.Two issues of Journals per year are published regularly.
  • 45.  Epidural anaesthesia  Epidural analgesia with catheter  Caudal anaesthesia with additives  Supraclavicular Brachial plexus block  Interscalene Brachial plexus block  Superficial cervical plexus block  Femoral nerve block
  • 46.  Now a days complicated surgical procedures like cardiac surgery ,neuro surgery,thoracic surgery,kidney transplant ,pain management and intensive care patients have been possible due to improvement of Anaesthesiology.  Still we are lacking of some basic infrastructural problems like -  -proper placement and distribution of manpower.  -Availabilty of equipments,  -Standard monitors and Drugs at all levels of health care .  However we are very mutch hopefull awaiting a golden future.