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e-Science at the
                  University of Minnesota
                                e-Science Symposium
                      National Network of Libraries of Medicine
                                 South Central Region
                            Texas Medical Center Library
                               Layne M. Johnson, Ph.D.
                                  February 13, 2012

©2012 Regents of the University of Minnesota. All rights reserved.
History, Evolution & Current State
 • Present my experiences as a researcher and show
   how changes in research call for the expertise of
   librarians and information specialists
 • Review the experiences at Minnesota and the
   roles that the University Library colleagues have
   played
 • Take a fresh look at the developing requirements
   and advances in e-science to best prepare
   ourselves and researchers to meet future needs

©2012 Regents of the University of Minnesota. All rights reserved.
First, Let’s Agree…
 • E-Science (or eScience) is computationally
   intensive scientific research, typically
   performed over distributed networks and
   involving large amounts of data. Also, e-
   science often involves collaboration.
 • E-Science can be referred to as E-Research to
   accommodate disciplines outside of the
   sciences, e.g. the Digital Humanities.

©2012 Regents of the University of Minnesota. All rights reserved.
E-Science
 • …has often been called cyberinfrastructure in
   the U.S.
 • Nowadays, cyberinfrastructure is used less (at
   least by me), and e-Science is used more
   frequently.




©2012 Regents of the University of Minnesota. All rights reserved.
Technology is the Major Impact on Science

                                                                     • High-throughput
                                                                       screening, sequencing
                                                                     • Equipment generating
                                                                       data 24/7
                                                                     • Information increasing
                                                                       logarithmically
                                                                     • Communications,
                                                                       networking
                                                                     • Regulations, standards

©2012 Regents of the University of Minnesota. All rights reserved.
Layne, the Bacteriologist




©2012 Regents of the University of Minnesota. All rights reserved.
Screening for New Medicines



                                                                           384 colonies

                                     24                  96          384

                                                                             What next?

                                Single colony

©2012 Regents of the University of Minnesota. All rights reserved.
Technology Increased Speed & Data Generation




©2012 Regents of the University of Minnesota. All rights reserved.
Manual Colony Selection Became Automated




                                                                     mRNA Microarrays [increased
      Aseptic Robotic Automation                                     #samples, increased sensitivity]


©2012 Regents of the University of Minnesota. All rights reserved.
More Data Requires (More) Computers
        # of data points generated
                                                                                        460800
                                     500000

                                     450000

                                     400000

                                     350000

                                     300000

                                     250000

                                     200000
                                                                           115200
                                     150000

                                     100000                  28800
                                     50000
                                                 240
                                          0

                                              1 Colony   24 Colonies   96 Colonies   384 Colonies


                                                Bacterial Colonies Tested
©2012 Regents of the University of Minnesota. All rights reserved.
Researchers & Computers Network to
   Manage Data – Share, Store, Analyze




©2012 Regents of the University of Minnesota. All rights reserved.
Reviewing our definition…

  …computationally intensive scientific research,
  typically performed over distributed networks
 and involving large amounts of data, with a dash
             of collaboration thrown in




©2012 Regents of the University of Minnesota. All rights reserved.
Which Leads to the Next Part of the Story




©2012 Regents of the University of Minnesota. All rights reserved.
Layne, the University of Minnesota
          Person / Gopher / Frozen Guy
         aka informationist, informaticist,
                   librarian, etc.




©2012 Regents of the University of Minnesota. All rights reserved.
Research at University of Minnesota
 • Twin Cities Campus
        – >52,000 students, 3400 faculty, 150 graduate and
          professional degrees
        – Medicine to business, law to liberal arts, science
          and engineering to architecture and agriculture
        – ~$770M in sponsored research in 2011, $305M
          from NIH
        – 2010 NSF research ranking – 8th among top 20
          public research universities in the US

©2012 Regents of the University of Minnesota. All rights reserved.
Academic Health Center (AHC)




©2012 Regents of the University of Minnesota. All rights reserved.
E-Science Landscape – 2006 - Present
 • Libraries developed a model for assessing
   research support – 2005-2006 – humanities,
   social sciences
 • 2006-2007 – analysis of science faculty and
   graduate students re: discovery, use, &
   management of data and information
 • 2007 – ARL report – “Agenda for Developing E-
   Science in Research Libraries” – W. Lougee
   coauthor

©2012 Regents of the University of Minnesota. All rights reserved.
E-Science Landscape – 2006 - Present
 • 2007+ - virtual community development –
   EthicShare, AgEcon
 • 2007-2009 – Cyberinfrastructure Alliance –
   University Libraries, IT, Office VP Research
 • 2010 – data audits, Research Networking
   implemented
 • 2010+ - Data Management workshops - >300
   faculty

©2012 Regents of the University of Minnesota. All rights reserved.
Things We’ve Learned from Researchers

 • Participants want
        – help with Data Management Plans (80%)
        – to share data with collaborators (84%)
        – to use metadata services (70%)
        – auto-backup data services (77%)
        – long term access to data (76%)
        – repositories for data on campus (e.g. GIS, 70%)


©2012 Regents of the University of Minnesota. All rights reserved.
Researchers also indicate they’d like:
 • to gain a better understanding of new data
   management and collaboration tools (76%)
 • to be able to not only identify experts, but
   also core resources, like biorepository
   samples, core centers of technology and
   methods & equipment support
 • to compete more aggressively for funding
   opportunities

©2012 Regents of the University of Minnesota. All rights reserved.
We used Charles Humphrey’s model of the
      Research Life Cycle to help inform or
  strategic direction for supporting e-science
         at the University of Minnesota
  (in the spirit of full disclosure, we modified
        the model – and so should you)


©2012 Regents of the University of Minnesota. All rights reserved.
The Research Life Cycle




©2012 Regents of the University of Minnesota. All rights reserved.
We Identified Library Roles
 • Content/Collection Development & Managing
   Datasets
 • Teaching and Learning
 • Outreach
 • Liaison Services
 • Translational Science and Informatics Support
 • Research Networking
 • Leadership

©2012 Regents of the University of Minnesota. All rights reserved.
Research Networking
 • We first implemented open source Harvard
   Profiles (UMN Profiles) - ~4,000 researchers
 • Collaboration with Office VP Research,
   Libraries, Colleges – we are implementing
   SciVal Experts, Funding, Spotlight
        – Got us at the table
        – Is pushing us into ontology work, linked open
          data, and the semantic web


©2012 Regents of the University of Minnesota. All rights reserved.
Data Management Plans (DMP)
 • Brief description of how primary
   investigator will comply with funder’s data
   sharing policy
 • Largest funding agencies include NIH and NSF




©2012 Regents of the University of Minnesota. All rights reserved.
Several DMP Tools Are Available
 • A variety of data management resources have
   been developed at by the University Libraries
   the University of Minnesota. Check into them
   at http://www.lib.umn.edu/datamanagement
 • For DMPs, see specifically:
   http://www.lib.umn.edu/datamanagement/D
   MP (take a look at the DMP checklist)


©2012 Regents of the University of Minnesota. All rights reserved.
DataOne (NSF) DMPs
 • Several examples are provided at:
   http://www.dataone.org/plans
 • DMPTool provides guidance and resources for
   your data management plan
        – Create plans
        – Meet funder requirements
        – Step by step instructions
        – Get data management advice


©2012 Regents of the University of Minnesota. All rights reserved.
Where Our Work is Leading Us
 • We realize that there are gaps in
   understanding privacy and security issues
   around data – especially in the health sciences
 • We also have identified gaps in our
   understanding of bench scientist (discovery,
   T1, pre-human) needs
 • We recognize an opportunity to transform
   several roles to support research and data
   needs

©2012 Regents of the University of Minnesota. All rights reserved.
Research Support and Services Collaboratives

 • Data Access Working Group
 • Research Communities and Networks
 • Digital Humanities

 • We see the boundaries between the Academic
   Health Center dissolving and a focus on
   enterprise solutions expanding
 • One example is the AHC Information Exchange
©2012 Regents of the University of Minnesota. All rights reserved.
AHC Information Exchange
 • Governance structure consisting of the SVP
   AHC, SVP of Research, CTSA PI
 • Working groups include informatics, research
   studies, architecture
        – Many groups request support from the libraries
        – Identity (like ORCID, etc.)
        – Metadata
        – Classification


©2012 Regents of the University of Minnesota. All rights reserved.
©2012 Regents of the University of Minnesota. All rights reserved.
Future of e-science
 • A positive development for libraries – it is
   important for us to take the lead
        – This is shown to be true from e-Science Institute
          activities with ARL
 • Need for open dialogue at all levels – local,
   regional, national, global
 • Opportunities abound – and can be leveraged
   with existing resources and sound strategies

©2012 Regents of the University of Minnesota. All rights reserved.
Acknowledgements
 • University of Minnesota Health Sciences
   Colleagues, particularly Andre Nault, Jonathan
   Koffel, Linda Watson
 • University Library colleagues, especially Lisa
   Johnston, John Butler, Meghan Lafferty,
   Wendy Lougee
 • Health Informatics Colleagues and Clinical and
   Translational Science Institute Colleagues
 • Cooper Mark Edward Johnson

©2012 Regents of the University of Minnesota. All rights reserved.

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Layne Johnson "e-Science at the Univeristy of Minnesota"

  • 1. e-Science at the University of Minnesota e-Science Symposium National Network of Libraries of Medicine South Central Region Texas Medical Center Library Layne M. Johnson, Ph.D. February 13, 2012 ©2012 Regents of the University of Minnesota. All rights reserved.
  • 2. History, Evolution & Current State • Present my experiences as a researcher and show how changes in research call for the expertise of librarians and information specialists • Review the experiences at Minnesota and the roles that the University Library colleagues have played • Take a fresh look at the developing requirements and advances in e-science to best prepare ourselves and researchers to meet future needs ©2012 Regents of the University of Minnesota. All rights reserved.
  • 3. First, Let’s Agree… • E-Science (or eScience) is computationally intensive scientific research, typically performed over distributed networks and involving large amounts of data. Also, e- science often involves collaboration. • E-Science can be referred to as E-Research to accommodate disciplines outside of the sciences, e.g. the Digital Humanities. ©2012 Regents of the University of Minnesota. All rights reserved.
  • 4. E-Science • …has often been called cyberinfrastructure in the U.S. • Nowadays, cyberinfrastructure is used less (at least by me), and e-Science is used more frequently. ©2012 Regents of the University of Minnesota. All rights reserved.
  • 5. Technology is the Major Impact on Science • High-throughput screening, sequencing • Equipment generating data 24/7 • Information increasing logarithmically • Communications, networking • Regulations, standards ©2012 Regents of the University of Minnesota. All rights reserved.
  • 6. Layne, the Bacteriologist ©2012 Regents of the University of Minnesota. All rights reserved.
  • 7. Screening for New Medicines 384 colonies 24 96 384 What next? Single colony ©2012 Regents of the University of Minnesota. All rights reserved.
  • 8. Technology Increased Speed & Data Generation ©2012 Regents of the University of Minnesota. All rights reserved.
  • 9. Manual Colony Selection Became Automated mRNA Microarrays [increased Aseptic Robotic Automation #samples, increased sensitivity] ©2012 Regents of the University of Minnesota. All rights reserved.
  • 10. More Data Requires (More) Computers # of data points generated 460800 500000 450000 400000 350000 300000 250000 200000 115200 150000 100000 28800 50000 240 0 1 Colony 24 Colonies 96 Colonies 384 Colonies Bacterial Colonies Tested ©2012 Regents of the University of Minnesota. All rights reserved.
  • 11. Researchers & Computers Network to Manage Data – Share, Store, Analyze ©2012 Regents of the University of Minnesota. All rights reserved.
  • 12. Reviewing our definition… …computationally intensive scientific research, typically performed over distributed networks and involving large amounts of data, with a dash of collaboration thrown in ©2012 Regents of the University of Minnesota. All rights reserved.
  • 13. Which Leads to the Next Part of the Story ©2012 Regents of the University of Minnesota. All rights reserved.
  • 14. Layne, the University of Minnesota Person / Gopher / Frozen Guy aka informationist, informaticist, librarian, etc. ©2012 Regents of the University of Minnesota. All rights reserved.
  • 15. Research at University of Minnesota • Twin Cities Campus – >52,000 students, 3400 faculty, 150 graduate and professional degrees – Medicine to business, law to liberal arts, science and engineering to architecture and agriculture – ~$770M in sponsored research in 2011, $305M from NIH – 2010 NSF research ranking – 8th among top 20 public research universities in the US ©2012 Regents of the University of Minnesota. All rights reserved.
  • 16. Academic Health Center (AHC) ©2012 Regents of the University of Minnesota. All rights reserved.
  • 17. E-Science Landscape – 2006 - Present • Libraries developed a model for assessing research support – 2005-2006 – humanities, social sciences • 2006-2007 – analysis of science faculty and graduate students re: discovery, use, & management of data and information • 2007 – ARL report – “Agenda for Developing E- Science in Research Libraries” – W. Lougee coauthor ©2012 Regents of the University of Minnesota. All rights reserved.
  • 18. E-Science Landscape – 2006 - Present • 2007+ - virtual community development – EthicShare, AgEcon • 2007-2009 – Cyberinfrastructure Alliance – University Libraries, IT, Office VP Research • 2010 – data audits, Research Networking implemented • 2010+ - Data Management workshops - >300 faculty ©2012 Regents of the University of Minnesota. All rights reserved.
  • 19. Things We’ve Learned from Researchers • Participants want – help with Data Management Plans (80%) – to share data with collaborators (84%) – to use metadata services (70%) – auto-backup data services (77%) – long term access to data (76%) – repositories for data on campus (e.g. GIS, 70%) ©2012 Regents of the University of Minnesota. All rights reserved.
  • 20. Researchers also indicate they’d like: • to gain a better understanding of new data management and collaboration tools (76%) • to be able to not only identify experts, but also core resources, like biorepository samples, core centers of technology and methods & equipment support • to compete more aggressively for funding opportunities ©2012 Regents of the University of Minnesota. All rights reserved.
  • 21. We used Charles Humphrey’s model of the Research Life Cycle to help inform or strategic direction for supporting e-science at the University of Minnesota (in the spirit of full disclosure, we modified the model – and so should you) ©2012 Regents of the University of Minnesota. All rights reserved.
  • 22. The Research Life Cycle ©2012 Regents of the University of Minnesota. All rights reserved.
  • 23. We Identified Library Roles • Content/Collection Development & Managing Datasets • Teaching and Learning • Outreach • Liaison Services • Translational Science and Informatics Support • Research Networking • Leadership ©2012 Regents of the University of Minnesota. All rights reserved.
  • 24. Research Networking • We first implemented open source Harvard Profiles (UMN Profiles) - ~4,000 researchers • Collaboration with Office VP Research, Libraries, Colleges – we are implementing SciVal Experts, Funding, Spotlight – Got us at the table – Is pushing us into ontology work, linked open data, and the semantic web ©2012 Regents of the University of Minnesota. All rights reserved.
  • 25. Data Management Plans (DMP) • Brief description of how primary investigator will comply with funder’s data sharing policy • Largest funding agencies include NIH and NSF ©2012 Regents of the University of Minnesota. All rights reserved.
  • 26. Several DMP Tools Are Available • A variety of data management resources have been developed at by the University Libraries the University of Minnesota. Check into them at http://www.lib.umn.edu/datamanagement • For DMPs, see specifically: http://www.lib.umn.edu/datamanagement/D MP (take a look at the DMP checklist) ©2012 Regents of the University of Minnesota. All rights reserved.
  • 27. DataOne (NSF) DMPs • Several examples are provided at: http://www.dataone.org/plans • DMPTool provides guidance and resources for your data management plan – Create plans – Meet funder requirements – Step by step instructions – Get data management advice ©2012 Regents of the University of Minnesota. All rights reserved.
  • 28. Where Our Work is Leading Us • We realize that there are gaps in understanding privacy and security issues around data – especially in the health sciences • We also have identified gaps in our understanding of bench scientist (discovery, T1, pre-human) needs • We recognize an opportunity to transform several roles to support research and data needs ©2012 Regents of the University of Minnesota. All rights reserved.
  • 29. Research Support and Services Collaboratives • Data Access Working Group • Research Communities and Networks • Digital Humanities • We see the boundaries between the Academic Health Center dissolving and a focus on enterprise solutions expanding • One example is the AHC Information Exchange ©2012 Regents of the University of Minnesota. All rights reserved.
  • 30. AHC Information Exchange • Governance structure consisting of the SVP AHC, SVP of Research, CTSA PI • Working groups include informatics, research studies, architecture – Many groups request support from the libraries – Identity (like ORCID, etc.) – Metadata – Classification ©2012 Regents of the University of Minnesota. All rights reserved.
  • 31. ©2012 Regents of the University of Minnesota. All rights reserved.
  • 32. Future of e-science • A positive development for libraries – it is important for us to take the lead – This is shown to be true from e-Science Institute activities with ARL • Need for open dialogue at all levels – local, regional, national, global • Opportunities abound – and can be leveraged with existing resources and sound strategies ©2012 Regents of the University of Minnesota. All rights reserved.
  • 33. Acknowledgements • University of Minnesota Health Sciences Colleagues, particularly Andre Nault, Jonathan Koffel, Linda Watson • University Library colleagues, especially Lisa Johnston, John Butler, Meghan Lafferty, Wendy Lougee • Health Informatics Colleagues and Clinical and Translational Science Institute Colleagues • Cooper Mark Edward Johnson ©2012 Regents of the University of Minnesota. All rights reserved.