The document discusses strategies for building a successful business in the cloud computing industry dominated by Amazon, Google, and Microsoft. It suggests focusing on developer communities, owning the end user experience rather than just being a cloud host, leveraging open source technology, making proprietary technology fill a weakness, focusing on areas too large for incumbents, using a multi-cloud strategy, addressing changes at the network edge, and leveraging blockchain technology. The key is taking a contrarian approach and being right about emerging trends to differentiate from the large cloud players.