SlideShare une entreprise Scribd logo

Global health, neglected diseases, and drug development -- a newcomer's perspective

•Télécharger en tant que PPT, PDF•
•
Greg Crowther
Greg Crowther

Greg Crowther's talk to Glacier Peak High School's "Biotechnology and Global Health" class.

Santé & Médecine
1  sur  16
Global health, neglected diseases, and drug development – a newcomer’s perspective Gregory J. Crowther, Ph.D. Department of Medicine University of Washington http://faculty.washington.edu/crowther/ early-stage research preclinical studies clinical trials (I) clinical trials (II) clinical trials (III) FDA review & approval market
What does that title mean? ,[object Object],[object Object],[object Object],about health disparities between rich & poor malaria, tuberculosis, dengue, filariasis, etc. early-stage research preclinical studies clinical trials (I) clinical trials (II) clinical trials (III) FDA review & approval market
“A shot at adulthood” video http://zooppa.com/ads/uw-pocket-media-film-festival/videos/a-shot-at-adulthood
Drug development for neglected diseases: Why is it so hard? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Image: tulane.edu/~wiser/
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Drug development for neglected diseases: Are there reasons for optimism?
What would a perfect drug be like? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
What would a perfect drug be like? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
What would a perfect drug be like? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Image: alphahelix.co.uk
What would a perfect drug be like? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Structure-based drug design Nelfinavir in the active site of HIV-1 protease. Image from C.M. Henry, C&EN 79 : 69, 2001.
Recent advances in malaria research: cool example #1 ,[object Object],[object Object],[object Object],[object Object],[object Object],Reference: F.J. Gamo et al., Nature 465 : 305, 2010
Recent advances in malaria drug research: cool example #2 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Reference: M. Rottmann et al., Science 329 : 1175, 2010
Conclusion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
T I M E S ’ U P
The malaria song ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],to the tune of “Maria” ( West Side Story ) music by Leonard Bernstein lyrics by Wes Van Voorhis, MD, PhD
Recent advances in malaria research: bonus example ,[object Object],[object Object],[object Object],[object Object],Reference: R. Gujjar et al., Journal of Medicinal Chemistry 52 : 1864, 2009.
Research frontier: the challenge of drug resistance and “polypharmacology” ,[object Object],[object Object],[object Object],[object Object],[object Object],Image from Chemical & Engineering News after M.J. Keiser et al., Nature 2009

Recommandé

HIV_Phylodynamics
HIV_PhylodynamicsHIV_Phylodynamics
HIV_PhylodynamicsLee Holmberg
 
Accessing Biomedical and Health Information
Accessing Biomedical and Health InformationAccessing Biomedical and Health Information
Accessing Biomedical and Health Informationmonicaduke
 
New body-on-a-chip technology to advance pharmacological research
New body-on-a-chip technology to advance pharmacological researchNew body-on-a-chip technology to advance pharmacological research
New body-on-a-chip technology to advance pharmacological researchsrrpenna
 
Parasitology - Exam 1 Flashcards _ Quizlet.pdf
Parasitology - Exam 1 Flashcards _ Quizlet.pdfParasitology - Exam 1 Flashcards _ Quizlet.pdf
Parasitology - Exam 1 Flashcards _ Quizlet.pdfrakydt
 
efficacy-of-a-recombinant-genotype-vii-vaccine-against-challenge-with-velogen...
efficacy-of-a-recombinant-genotype-vii-vaccine-against-challenge-with-velogen...efficacy-of-a-recombinant-genotype-vii-vaccine-against-challenge-with-velogen...
efficacy-of-a-recombinant-genotype-vii-vaccine-against-challenge-with-velogen...Peertechz Publications
 
Dennis Sheeter, Vita 0116
Dennis Sheeter, Vita 0116Dennis Sheeter, Vita 0116
Dennis Sheeter, Vita 0116Dennis Sheeter
 
English Power Point
English Power PointEnglish Power Point
English Power PointJohn Ward
 
PATH Malaria Vaccine Initiative
PATH Malaria Vaccine InitiativePATH Malaria Vaccine Initiative
PATH Malaria Vaccine InitiativeTRAIN Central Station
 

Recommandé

HIV_Phylodynamics
HIV_PhylodynamicsHIV_Phylodynamics
HIV_PhylodynamicsLee Holmberg
 
Accessing Biomedical and Health Information
Accessing Biomedical and Health InformationAccessing Biomedical and Health Information
Accessing Biomedical and Health Informationmonicaduke
 
New body-on-a-chip technology to advance pharmacological research
New body-on-a-chip technology to advance pharmacological researchNew body-on-a-chip technology to advance pharmacological research
New body-on-a-chip technology to advance pharmacological researchsrrpenna
 
Parasitology - Exam 1 Flashcards _ Quizlet.pdf
Parasitology - Exam 1 Flashcards _ Quizlet.pdfParasitology - Exam 1 Flashcards _ Quizlet.pdf
Parasitology - Exam 1 Flashcards _ Quizlet.pdfrakydt
 
efficacy-of-a-recombinant-genotype-vii-vaccine-against-challenge-with-velogen...
efficacy-of-a-recombinant-genotype-vii-vaccine-against-challenge-with-velogen...efficacy-of-a-recombinant-genotype-vii-vaccine-against-challenge-with-velogen...
efficacy-of-a-recombinant-genotype-vii-vaccine-against-challenge-with-velogen...Peertechz Publications
 
Dennis Sheeter, Vita 0116
Dennis Sheeter, Vita 0116Dennis Sheeter, Vita 0116
Dennis Sheeter, Vita 0116Dennis Sheeter
 
English Power Point
English Power PointEnglish Power Point
English Power PointJohn Ward
 
PATH Malaria Vaccine Initiative
PATH Malaria Vaccine InitiativePATH Malaria Vaccine Initiative
PATH Malaria Vaccine InitiativeTRAIN Central Station
 
An analysis of metabolic fluxes in contracting human muscle
An analysis of metabolic fluxes in contracting human muscleAn analysis of metabolic fluxes in contracting human muscle
An analysis of metabolic fluxes in contracting human muscleGreg Crowther
 
Is Brugia malayi’s cofactor-independent phosphoglycerate mutase (iPGM) drugga...
Is Brugia malayi’s cofactor-independent phosphoglycerate mutase (iPGM) drugga...Is Brugia malayi’s cofactor-independent phosphoglycerate mutase (iPGM) drugga...
Is Brugia malayi’s cofactor-independent phosphoglycerate mutase (iPGM) drugga...Greg Crowther
 
The Do-Re-Mi's of A&P: teaching interactively with content-rich jingles
The Do-Re-Mi's of A&P: teaching interactively with content-rich jinglesThe Do-Re-Mi's of A&P: teaching interactively with content-rich jingles
The Do-Re-Mi's of A&P: teaching interactively with content-rich jinglesGreg Crowther
 
New insights into the metabolic network of Methylobacterium extorquens AM1
New insights into the metabolic network of Methylobacterium extorquens AM1New insights into the metabolic network of Methylobacterium extorquens AM1
New insights into the metabolic network of Methylobacterium extorquens AM1Greg Crowther
 
TDRtargets.org: an open-access resource for prioritizing possible drug target...
TDRtargets.org: an open-access resource for prioritizing possible drug target...TDRtargets.org: an open-access resource for prioritizing possible drug target...
TDRtargets.org: an open-access resource for prioritizing possible drug target...Greg Crowther
 
Learning from the primary literature: selected approaches
Learning from the primary literature: selected approachesLearning from the primary literature: selected approaches
Learning from the primary literature: selected approachesGreg Crowther
 
Learning from the primary literature: selected approaches
Learning from the primary literature: selected approachesLearning from the primary literature: selected approaches
Learning from the primary literature: selected approachesGreg Crowther
 
Open Source Pharma Foundation
Open Source Pharma FoundationOpen Source Pharma Foundation
Open Source Pharma FoundationPrateekGarg76472
 
Lean launch pad for Life Sciences and Health Care
Lean launch pad for Life Sciences and Health CareLean launch pad for Life Sciences and Health Care
Lean launch pad for Life Sciences and Health CareStanford University
 
Human Genome Project
Human Genome ProjectHuman Genome Project
Human Genome ProjectMuhammadIslam136
 
Vaccines
VaccinesVaccines
VaccinesBill Vanderbilt
 
Visual arguement
Visual arguementVisual arguement
Visual arguementashearer2012
 
PA 513 Lisa Lasker Policy and Evaluation Final
PA 513 Lisa Lasker Policy and Evaluation FinalPA 513 Lisa Lasker Policy and Evaluation Final
PA 513 Lisa Lasker Policy and Evaluation FinalLisa Lasker
 
Exposure to environmental and Occupational toxins and Human Health-Genotoxici...
Exposure to environmental and Occupational toxins and Human Health-Genotoxici...Exposure to environmental and Occupational toxins and Human Health-Genotoxici...
Exposure to environmental and Occupational toxins and Human Health-Genotoxici...Vikas Dighe
 
Gennaro D'Urso: PharmaDAO - The future of Medicine
Gennaro D'Urso: PharmaDAO - The future of MedicineGennaro D'Urso: PharmaDAO - The future of Medicine
Gennaro D'Urso: PharmaDAO - The future of MedicineEdunomica
 
Phage Therapy_ Past, Present and Future.pdf
Phage Therapy_ Past, Present and Future.pdfPhage Therapy_ Past, Present and Future.pdf
Phage Therapy_ Past, Present and Future.pdfSubburamu Karthikeyan
 
Faster Cures For All
Faster Cures For AllFaster Cures For All
Faster Cures For AllGeoffrey Siwo
 
Personalized Medicine: Balancing the Promise and Peril of ... Personalized ...
Personalized Medicine: Balancing the Promise and Peril of ... Personalized ...Personalized Medicine: Balancing the Promise and Peril of ... Personalized ...
Personalized Medicine: Balancing the Promise and Peril of ... Personalized ...MedicineAndHealth
 
America's Chemical Brain Drain & Autism - Looking for the Environmental Culpr...
America's Chemical Brain Drain & Autism - Looking for the Environmental Culpr...America's Chemical Brain Drain & Autism - Looking for the Environmental Culpr...
America's Chemical Brain Drain & Autism - Looking for the Environmental Culpr...v2zq
 
Organs on chip ppt
Organs on chip pptOrgans on chip ppt
Organs on chip pptkavya rao
 
Organs on chip ppt
Organs on chip pptOrgans on chip ppt
Organs on chip pptkavya rao
 
Drug repurposing
Drug repurposingDrug repurposing
Drug repurposingEURORDIS Rare Diseases Europe
 

Contenu connexe

En vedette

An analysis of metabolic fluxes in contracting human muscle
An analysis of metabolic fluxes in contracting human muscleAn analysis of metabolic fluxes in contracting human muscle
An analysis of metabolic fluxes in contracting human muscleGreg Crowther
 
Is Brugia malayi’s cofactor-independent phosphoglycerate mutase (iPGM) drugga...
Is Brugia malayi’s cofactor-independent phosphoglycerate mutase (iPGM) drugga...Is Brugia malayi’s cofactor-independent phosphoglycerate mutase (iPGM) drugga...
Is Brugia malayi’s cofactor-independent phosphoglycerate mutase (iPGM) drugga...Greg Crowther
 
The Do-Re-Mi's of A&P: teaching interactively with content-rich jingles
The Do-Re-Mi's of A&P: teaching interactively with content-rich jinglesThe Do-Re-Mi's of A&P: teaching interactively with content-rich jingles
The Do-Re-Mi's of A&P: teaching interactively with content-rich jinglesGreg Crowther
 
New insights into the metabolic network of Methylobacterium extorquens AM1
New insights into the metabolic network of Methylobacterium extorquens AM1New insights into the metabolic network of Methylobacterium extorquens AM1
New insights into the metabolic network of Methylobacterium extorquens AM1Greg Crowther
 
TDRtargets.org: an open-access resource for prioritizing possible drug target...
TDRtargets.org: an open-access resource for prioritizing possible drug target...TDRtargets.org: an open-access resource for prioritizing possible drug target...
TDRtargets.org: an open-access resource for prioritizing possible drug target...Greg Crowther
 
Learning from the primary literature: selected approaches
Learning from the primary literature: selected approachesLearning from the primary literature: selected approaches
Learning from the primary literature: selected approachesGreg Crowther
 
Learning from the primary literature: selected approaches
Learning from the primary literature: selected approachesLearning from the primary literature: selected approaches
Learning from the primary literature: selected approachesGreg Crowther
 

En vedette (7)

An analysis of metabolic fluxes in contracting human muscle
An analysis of metabolic fluxes in contracting human muscleAn analysis of metabolic fluxes in contracting human muscle
An analysis of metabolic fluxes in contracting human muscle
 
Is Brugia malayi’s cofactor-independent phosphoglycerate mutase (iPGM) drugga...
Is Brugia malayi’s cofactor-independent phosphoglycerate mutase (iPGM) drugga...Is Brugia malayi’s cofactor-independent phosphoglycerate mutase (iPGM) drugga...
Is Brugia malayi’s cofactor-independent phosphoglycerate mutase (iPGM) drugga...
 
The Do-Re-Mi's of A&P: teaching interactively with content-rich jingles
The Do-Re-Mi's of A&P: teaching interactively with content-rich jinglesThe Do-Re-Mi's of A&P: teaching interactively with content-rich jingles
The Do-Re-Mi's of A&P: teaching interactively with content-rich jingles
 
New insights into the metabolic network of Methylobacterium extorquens AM1
New insights into the metabolic network of Methylobacterium extorquens AM1New insights into the metabolic network of Methylobacterium extorquens AM1
New insights into the metabolic network of Methylobacterium extorquens AM1
 
TDRtargets.org: an open-access resource for prioritizing possible drug target...
TDRtargets.org: an open-access resource for prioritizing possible drug target...TDRtargets.org: an open-access resource for prioritizing possible drug target...
TDRtargets.org: an open-access resource for prioritizing possible drug target...
 
Learning from the primary literature: selected approaches
Learning from the primary literature: selected approachesLearning from the primary literature: selected approaches
Learning from the primary literature: selected approaches
 
Learning from the primary literature: selected approaches
Learning from the primary literature: selected approachesLearning from the primary literature: selected approaches
Learning from the primary literature: selected approaches
 

Similaire à Global health, neglected diseases, and drug development -- a newcomer's perspective

Open Source Pharma Foundation
Open Source Pharma FoundationOpen Source Pharma Foundation
Open Source Pharma FoundationPrateekGarg76472
 
Lean launch pad for Life Sciences and Health Care
Lean launch pad for Life Sciences and Health CareLean launch pad for Life Sciences and Health Care
Lean launch pad for Life Sciences and Health CareStanford University
 
PA 513 Lisa Lasker Policy and Evaluation Final
PA 513 Lisa Lasker Policy and Evaluation FinalPA 513 Lisa Lasker Policy and Evaluation Final
PA 513 Lisa Lasker Policy and Evaluation FinalLisa Lasker
 
Exposure to environmental and Occupational toxins and Human Health-Genotoxici...
Exposure to environmental and Occupational toxins and Human Health-Genotoxici...Exposure to environmental and Occupational toxins and Human Health-Genotoxici...
Exposure to environmental and Occupational toxins and Human Health-Genotoxici...Vikas Dighe
 
Gennaro D'Urso: PharmaDAO - The future of Medicine
Gennaro D'Urso: PharmaDAO - The future of MedicineGennaro D'Urso: PharmaDAO - The future of Medicine
Gennaro D'Urso: PharmaDAO - The future of MedicineEdunomica
 
Phage Therapy_ Past, Present and Future.pdf
Phage Therapy_ Past, Present and Future.pdfPhage Therapy_ Past, Present and Future.pdf
Phage Therapy_ Past, Present and Future.pdfSubburamu Karthikeyan
 
Faster Cures For All
Faster Cures For AllFaster Cures For All
Faster Cures For AllGeoffrey Siwo
 
Personalized Medicine: Balancing the Promise and Peril of ... Personalized ...
Personalized Medicine: Balancing the Promise and Peril of ... Personalized ...Personalized Medicine: Balancing the Promise and Peril of ... Personalized ...
Personalized Medicine: Balancing the Promise and Peril of ... Personalized ...MedicineAndHealth
 
America's Chemical Brain Drain & Autism - Looking for the Environmental Culpr...
America's Chemical Brain Drain & Autism - Looking for the Environmental Culpr...America's Chemical Brain Drain & Autism - Looking for the Environmental Culpr...
America's Chemical Brain Drain & Autism - Looking for the Environmental Culpr...v2zq
 
Organs on chip ppt
Organs on chip pptOrgans on chip ppt
Organs on chip pptkavya rao
 
Organs on chip ppt
Organs on chip pptOrgans on chip ppt
Organs on chip pptkavya rao
 
Slides for rare disorders meeting
Slides for rare disorders meetingSlides for rare disorders meeting
Slides for rare disorders meetingSean Ekins
 
Non animal technology the future is amazing, and animal-free. #vivisection ...
Non animal technology the future is amazing, and animal-free. #vivisection ...Non animal technology the future is amazing, and animal-free. #vivisection ...
Non animal technology the future is amazing, and animal-free. #vivisection ...All Animal Rights
 
Drug development process
Drug development processDrug development process
Drug development processnasim arshadi
 
Genomics in Public Health
Genomics in Public HealthGenomics in Public Health
Genomics in Public HealthJennifer Gardy
 

Similaire à Global health, neglected diseases, and drug development -- a newcomer's perspective (20)

Open Source Pharma Foundation
Open Source Pharma FoundationOpen Source Pharma Foundation
Open Source Pharma Foundation
 
Lean launch pad for Life Sciences and Health Care
Lean launch pad for Life Sciences and Health CareLean launch pad for Life Sciences and Health Care
Lean launch pad for Life Sciences and Health Care
 
Human Genome Project
Human Genome ProjectHuman Genome Project
Human Genome Project
 
Vaccines
VaccinesVaccines
Vaccines
 
Visual arguement
Visual arguementVisual arguement
Visual arguement
 
PA 513 Lisa Lasker Policy and Evaluation Final
PA 513 Lisa Lasker Policy and Evaluation FinalPA 513 Lisa Lasker Policy and Evaluation Final
PA 513 Lisa Lasker Policy and Evaluation Final
 
Exposure to environmental and Occupational toxins and Human Health-Genotoxici...
Exposure to environmental and Occupational toxins and Human Health-Genotoxici...Exposure to environmental and Occupational toxins and Human Health-Genotoxici...
Exposure to environmental and Occupational toxins and Human Health-Genotoxici...
 
Gennaro D'Urso: PharmaDAO - The future of Medicine
Gennaro D'Urso: PharmaDAO - The future of MedicineGennaro D'Urso: PharmaDAO - The future of Medicine
Gennaro D'Urso: PharmaDAO - The future of Medicine
 
Phage Therapy_ Past, Present and Future.pdf
Phage Therapy_ Past, Present and Future.pdfPhage Therapy_ Past, Present and Future.pdf
Phage Therapy_ Past, Present and Future.pdf
 
Faster Cures For All
Faster Cures For AllFaster Cures For All
Faster Cures For All
 
Personalized Medicine: Balancing the Promise and Peril of ... Personalized ...
Personalized Medicine: Balancing the Promise and Peril of ... Personalized ...Personalized Medicine: Balancing the Promise and Peril of ... Personalized ...
Personalized Medicine: Balancing the Promise and Peril of ... Personalized ...
 
America's Chemical Brain Drain & Autism - Looking for the Environmental Culpr...
America's Chemical Brain Drain & Autism - Looking for the Environmental Culpr...America's Chemical Brain Drain & Autism - Looking for the Environmental Culpr...
America's Chemical Brain Drain & Autism - Looking for the Environmental Culpr...
 
Organs on chip ppt
Organs on chip pptOrgans on chip ppt
Organs on chip ppt
 
Organs on chip ppt
Organs on chip pptOrgans on chip ppt
Organs on chip ppt
 
Drug repurposing
Drug repurposingDrug repurposing
Drug repurposing
 
Slides for rare disorders meeting
Slides for rare disorders meetingSlides for rare disorders meeting
Slides for rare disorders meeting
 
Gene therapy
Gene therapyGene therapy
Gene therapy
 
Non animal technology the future is amazing, and animal-free. #vivisection ...
Non animal technology the future is amazing, and animal-free. #vivisection ...Non animal technology the future is amazing, and animal-free. #vivisection ...
Non animal technology the future is amazing, and animal-free. #vivisection ...
 
Drug development process
Drug development processDrug development process
Drug development process
 
Genomics in Public Health
Genomics in Public HealthGenomics in Public Health
Genomics in Public Health
 

Plus de Greg Crowther

Teaching science with music: so many models, so little data
Teaching science with music: so many models, so little dataTeaching science with music: so many models, so little data
Teaching science with music: so many models, so little dataGreg Crowther
 
Genetically engineered bacteria: chemical factories of the future?
Genetically engineered bacteria: chemical factories of the future?Genetically engineered bacteria: chemical factories of the future?
Genetically engineered bacteria: chemical factories of the future?Greg Crowther
 
Methylobacterium extorquens: Metabolic superstar
Methylobacterium extorquens: Metabolic superstarMethylobacterium extorquens: Metabolic superstar
Methylobacterium extorquens: Metabolic superstarGreg Crowther
 
Biochemical and bioinformatic investigations of potential drug targets in Pla...
Biochemical and bioinformatic investigations of potential drug targets in Pla...Biochemical and bioinformatic investigations of potential drug targets in Pla...
Biochemical and bioinformatic investigations of potential drug targets in Pla...Greg Crowther
 
Alcohol consumption as a way of life: the metabolism of methylotrophic bacteria
Alcohol consumption as a way of life: the metabolism of methylotrophic bacteriaAlcohol consumption as a way of life: the metabolism of methylotrophic bacteria
Alcohol consumption as a way of life: the metabolism of methylotrophic bacteriaGreg Crowther
 
If You Give Phil A Cookie
If You Give Phil A CookieIf You Give Phil A Cookie
If You Give Phil A CookieGreg Crowther
 
The Wheels On The Bike
The Wheels On The BikeThe Wheels On The Bike
The Wheels On The BikeGreg Crowther
 

Plus de Greg Crowther (7)

Teaching science with music: so many models, so little data
Teaching science with music: so many models, so little dataTeaching science with music: so many models, so little data
Teaching science with music: so many models, so little data
 
Genetically engineered bacteria: chemical factories of the future?
Genetically engineered bacteria: chemical factories of the future?Genetically engineered bacteria: chemical factories of the future?
Genetically engineered bacteria: chemical factories of the future?
 
Methylobacterium extorquens: Metabolic superstar
Methylobacterium extorquens: Metabolic superstarMethylobacterium extorquens: Metabolic superstar
Methylobacterium extorquens: Metabolic superstar
 
Biochemical and bioinformatic investigations of potential drug targets in Pla...
Biochemical and bioinformatic investigations of potential drug targets in Pla...Biochemical and bioinformatic investigations of potential drug targets in Pla...
Biochemical and bioinformatic investigations of potential drug targets in Pla...
 
Alcohol consumption as a way of life: the metabolism of methylotrophic bacteria
Alcohol consumption as a way of life: the metabolism of methylotrophic bacteriaAlcohol consumption as a way of life: the metabolism of methylotrophic bacteria
Alcohol consumption as a way of life: the metabolism of methylotrophic bacteria
 
If You Give Phil A Cookie
If You Give Phil A CookieIf You Give Phil A Cookie
If You Give Phil A Cookie
 
The Wheels On The Bike
The Wheels On The BikeThe Wheels On The Bike
The Wheels On The Bike
 

Dernier

Call Girl Bangalore Nandini 7001305949 Independent Escort Service Bangalore
Call Girl Bangalore Nandini 7001305949 Independent Escort Service BangaloreCall Girl Bangalore Nandini 7001305949 Independent Escort Service Bangalore
Call Girl Bangalore Nandini 7001305949 Independent Escort Service Bangalorenarwatsonia7
 
Asthma Review - GINA guidelines summary 2024
Asthma Review - GINA guidelines summary 2024Asthma Review - GINA guidelines summary 2024
Asthma Review - GINA guidelines summary 2024Gabriel Guevara MD
 
Call Girls ITPL Just Call 7001305949 Top Class Call Girl Service Available
Call Girls ITPL Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls ITPL Just Call 7001305949 Top Class Call Girl Service Available
Call Girls ITPL Just Call 7001305949 Top Class Call Girl Service Availablenarwatsonia7
 
Call Girls Hosur Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hosur Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls Hosur Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hosur Just Call 7001305949 Top Class Call Girl Service Availablenarwatsonia7
 
Call Girls Service In Shyam Nagar Whatsapp 8445551418 Independent Escort Service
Call Girls Service In Shyam Nagar Whatsapp 8445551418 Independent Escort ServiceCall Girls Service In Shyam Nagar Whatsapp 8445551418 Independent Escort Service
Call Girls Service In Shyam Nagar Whatsapp 8445551418 Independent Escort Serviceparulsinha
 
See the 2,456 pharmacies on the National E-Pharmacy Platform
See the 2,456 pharmacies on the National E-Pharmacy PlatformSee the 2,456 pharmacies on the National E-Pharmacy Platform
See the 2,456 pharmacies on the National E-Pharmacy PlatformKweku Zurek
 
Low Rate Call Girls Pune Esha 9907093804 Short 1500 Night 6000 Best call girl...
Low Rate Call Girls Pune Esha 9907093804 Short 1500 Night 6000 Best call girl...Low Rate Call Girls Pune Esha 9907093804 Short 1500 Night 6000 Best call girl...
Low Rate Call Girls Pune Esha 9907093804 Short 1500 Night 6000 Best call girl...Miss joya
 
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbers
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbersBook Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbers
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbersnarwatsonia7
 
Call Girl Service Bidadi - For 7001305949 Cheap & Best with original Photos
Call Girl Service Bidadi - For 7001305949 Cheap & Best with original PhotosCall Girl Service Bidadi - For 7001305949 Cheap & Best with original Photos
Call Girl Service Bidadi - For 7001305949 Cheap & Best with original Photosnarwatsonia7
 
VIP Call Girls Pune Vrinda 9907093804 Short 1500 Night 6000 Best call girls S...
VIP Call Girls Pune Vrinda 9907093804 Short 1500 Night 6000 Best call girls S...VIP Call Girls Pune Vrinda 9907093804 Short 1500 Night 6000 Best call girls S...
VIP Call Girls Pune Vrinda 9907093804 Short 1500 Night 6000 Best call girls S...Miss joya
 
Call Girls Hsr Layout Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hsr Layout Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls Hsr Layout Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hsr Layout Just Call 7001305949 Top Class Call Girl Service Availablenarwatsonia7
 
call girls in green park DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in green park DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️call girls in green park DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in green park DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️saminamagar
 
Call Girl Lucknow Mallika 7001305949 Independent Escort Service Lucknow
Call Girl Lucknow Mallika 7001305949 Independent Escort Service LucknowCall Girl Lucknow Mallika 7001305949 Independent Escort Service Lucknow
Call Girl Lucknow Mallika 7001305949 Independent Escort Service Lucknownarwatsonia7
 
Housewife Call Girls Bangalore - Call 7001305949 Rs-3500 with A/C Room Cash o...
Housewife Call Girls Bangalore - Call 7001305949 Rs-3500 with A/C Room Cash o...Housewife Call Girls Bangalore - Call 7001305949 Rs-3500 with A/C Room Cash o...
Housewife Call Girls Bangalore - Call 7001305949 Rs-3500 with A/C Room Cash o...narwatsonia7
 
Call Girls Kanakapura Road Just Call 7001305949 Top Class Call Girl Service A...
Call Girls Kanakapura Road Just Call 7001305949 Top Class Call Girl Service A...Call Girls Kanakapura Road Just Call 7001305949 Top Class Call Girl Service A...
Call Girls Kanakapura Road Just Call 7001305949 Top Class Call Girl Service A...narwatsonia7
 
VIP Call Girls Mumbai Arpita 9910780858 Independent Escort Service Mumbai
VIP Call Girls Mumbai Arpita 9910780858 Independent Escort Service MumbaiVIP Call Girls Mumbai Arpita 9910780858 Independent Escort Service Mumbai
VIP Call Girls Mumbai Arpita 9910780858 Independent Escort Service Mumbaisonalikaur4
 
Mumbai Call Girls Service 9910780858 Real Russian Girls Looking Models
Mumbai Call Girls Service 9910780858 Real Russian Girls Looking ModelsMumbai Call Girls Service 9910780858 Real Russian Girls Looking Models
Mumbai Call Girls Service 9910780858 Real Russian Girls Looking Modelssonalikaur4
 
College Call Girls Pune Mira 9907093804 Short 1500 Night 6000 Best call girls...
College Call Girls Pune Mira 9907093804 Short 1500 Night 6000 Best call girls...College Call Girls Pune Mira 9907093804 Short 1500 Night 6000 Best call girls...
College Call Girls Pune Mira 9907093804 Short 1500 Night 6000 Best call girls...Miss joya
 
Russian Call Girls Chickpet - 7001305949 Booking and charges genuine rate for...
Russian Call Girls Chickpet - 7001305949 Booking and charges genuine rate for...Russian Call Girls Chickpet - 7001305949 Booking and charges genuine rate for...
Russian Call Girls Chickpet - 7001305949 Booking and charges genuine rate for...narwatsonia7
 
Call Girls Whitefield Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Whitefield Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls Whitefield Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Whitefield Just Call 7001305949 Top Class Call Girl Service Availablenarwatsonia7
 

Dernier (20)

Call Girl Bangalore Nandini 7001305949 Independent Escort Service Bangalore
Call Girl Bangalore Nandini 7001305949 Independent Escort Service BangaloreCall Girl Bangalore Nandini 7001305949 Independent Escort Service Bangalore
Call Girl Bangalore Nandini 7001305949 Independent Escort Service Bangalore
 
Asthma Review - GINA guidelines summary 2024
Asthma Review - GINA guidelines summary 2024Asthma Review - GINA guidelines summary 2024
Asthma Review - GINA guidelines summary 2024
 
Call Girls ITPL Just Call 7001305949 Top Class Call Girl Service Available
Call Girls ITPL Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls ITPL Just Call 7001305949 Top Class Call Girl Service Available
Call Girls ITPL Just Call 7001305949 Top Class Call Girl Service Available
 
Call Girls Hosur Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hosur Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls Hosur Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hosur Just Call 7001305949 Top Class Call Girl Service Available
 
Call Girls Service In Shyam Nagar Whatsapp 8445551418 Independent Escort Service
Call Girls Service In Shyam Nagar Whatsapp 8445551418 Independent Escort ServiceCall Girls Service In Shyam Nagar Whatsapp 8445551418 Independent Escort Service
Call Girls Service In Shyam Nagar Whatsapp 8445551418 Independent Escort Service
 
See the 2,456 pharmacies on the National E-Pharmacy Platform
See the 2,456 pharmacies on the National E-Pharmacy PlatformSee the 2,456 pharmacies on the National E-Pharmacy Platform
See the 2,456 pharmacies on the National E-Pharmacy Platform
 
Low Rate Call Girls Pune Esha 9907093804 Short 1500 Night 6000 Best call girl...
Low Rate Call Girls Pune Esha 9907093804 Short 1500 Night 6000 Best call girl...Low Rate Call Girls Pune Esha 9907093804 Short 1500 Night 6000 Best call girl...
Low Rate Call Girls Pune Esha 9907093804 Short 1500 Night 6000 Best call girl...
 
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbers
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbersBook Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbers
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbers
 
Call Girl Service Bidadi - For 7001305949 Cheap & Best with original Photos
Call Girl Service Bidadi - For 7001305949 Cheap & Best with original PhotosCall Girl Service Bidadi - For 7001305949 Cheap & Best with original Photos
Call Girl Service Bidadi - For 7001305949 Cheap & Best with original Photos
 
VIP Call Girls Pune Vrinda 9907093804 Short 1500 Night 6000 Best call girls S...
VIP Call Girls Pune Vrinda 9907093804 Short 1500 Night 6000 Best call girls S...VIP Call Girls Pune Vrinda 9907093804 Short 1500 Night 6000 Best call girls S...
VIP Call Girls Pune Vrinda 9907093804 Short 1500 Night 6000 Best call girls S...
 
Call Girls Hsr Layout Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hsr Layout Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls Hsr Layout Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hsr Layout Just Call 7001305949 Top Class Call Girl Service Available
 
call girls in green park DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in green park DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️call girls in green park DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in green park DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
 
Call Girl Lucknow Mallika 7001305949 Independent Escort Service Lucknow
Call Girl Lucknow Mallika 7001305949 Independent Escort Service LucknowCall Girl Lucknow Mallika 7001305949 Independent Escort Service Lucknow
Call Girl Lucknow Mallika 7001305949 Independent Escort Service Lucknow
 
Housewife Call Girls Bangalore - Call 7001305949 Rs-3500 with A/C Room Cash o...
Housewife Call Girls Bangalore - Call 7001305949 Rs-3500 with A/C Room Cash o...Housewife Call Girls Bangalore - Call 7001305949 Rs-3500 with A/C Room Cash o...
Housewife Call Girls Bangalore - Call 7001305949 Rs-3500 with A/C Room Cash o...
 
Call Girls Kanakapura Road Just Call 7001305949 Top Class Call Girl Service A...
Call Girls Kanakapura Road Just Call 7001305949 Top Class Call Girl Service A...Call Girls Kanakapura Road Just Call 7001305949 Top Class Call Girl Service A...
Call Girls Kanakapura Road Just Call 7001305949 Top Class Call Girl Service A...
 
VIP Call Girls Mumbai Arpita 9910780858 Independent Escort Service Mumbai
VIP Call Girls Mumbai Arpita 9910780858 Independent Escort Service MumbaiVIP Call Girls Mumbai Arpita 9910780858 Independent Escort Service Mumbai
VIP Call Girls Mumbai Arpita 9910780858 Independent Escort Service Mumbai
 
Mumbai Call Girls Service 9910780858 Real Russian Girls Looking Models
Mumbai Call Girls Service 9910780858 Real Russian Girls Looking ModelsMumbai Call Girls Service 9910780858 Real Russian Girls Looking Models
Mumbai Call Girls Service 9910780858 Real Russian Girls Looking Models
 
College Call Girls Pune Mira 9907093804 Short 1500 Night 6000 Best call girls...
College Call Girls Pune Mira 9907093804 Short 1500 Night 6000 Best call girls...College Call Girls Pune Mira 9907093804 Short 1500 Night 6000 Best call girls...
College Call Girls Pune Mira 9907093804 Short 1500 Night 6000 Best call girls...
 
Russian Call Girls Chickpet - 7001305949 Booking and charges genuine rate for...
Russian Call Girls Chickpet - 7001305949 Booking and charges genuine rate for...Russian Call Girls Chickpet - 7001305949 Booking and charges genuine rate for...
Russian Call Girls Chickpet - 7001305949 Booking and charges genuine rate for...
 
Call Girls Whitefield Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Whitefield Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls Whitefield Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Whitefield Just Call 7001305949 Top Class Call Girl Service Available
 

Global health, neglected diseases, and drug development -- a newcomer's perspective

  • 1. Global health, neglected diseases, and drug development – a newcomer’s perspective Gregory J. Crowther, Ph.D. Department of Medicine University of Washington http://faculty.washington.edu/crowther/ early-stage research preclinical studies clinical trials (I) clinical trials (II) clinical trials (III) FDA review & approval market
  • 2.
  • 3. “A shot at adulthood” video http://zooppa.com/ads/uw-pocket-media-film-festival/videos/a-shot-at-adulthood
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13. T I M E S ’ U P
  • 14.
  • 15.
  • 16.