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Intelligent Health Lab
Kenneth D. Mandl, MD, MPH
Director, Intelligent Health Laboratory
Children’s Hospital Informatics Program
Center for Biomedical Informatics, Harvard
The App Store for Health:
Co-opting the Point of Care
in the Era of the Affordable Care Act
Intelligent Health Lab
US Spending per capita vs. Life Expectancy
Intelligent Health Lab
Learning Health System: Evidence Generated
from a Well-Instrumented Health System
Intelligent Health Lab
? How do we learn from
“All the Patients . . .
All the Time?”
(Instead of Some of the
Patients All of the Time . . . )
. . . or really, just a couple of
the patients, not that often.
Intelligent Health Lab
Intelligent Health Lab
Dr. Collins discussing the
Rapid Learning Network
Intelligent Health Lab
WITHOUT ACCESS TO THE
POINT OF CARE,
EVERYTHING IS A ONE-OFF
Intelligent Health Lab
Intelligent Health Laboratory | Children‘s Hospital Informatics
Program
Intelligent Health Lab
Returning Genomic Medicine Results
Intelligent Health Lab
Intelligent Health Lab
The App Store for Health
ONC Funded Research $15M Project under the
“SHARP” program
Intelligent Health Lab
Can EMRs behave
like iPhones or
Androids in that
innovators
readily create and
widely distribute
apps across
thousands of
installs?
Intelligent Health Lab
Our vocabulary
 Data Sources
Managed by containers
 Containers
Present data from data sources to apps in a uniform 
fashion
 Apps
Completely substitutable
Intelligent Health Lab
18.12 Issue
Intelligent Health Lab
State-of-the-Art ???
Intelligent Health Lab
Intelligent Health Lab
1 Design + 1 Developer + 1 Week
Intelligent Health Lab
1 SMART App in 3 SMART Systems
Intelligent Health Lab
Well-publicized
Intelligent Health Lab
Intelligent Health Lab
SMART
BP Centiles App
Running on Cerner
Intelligent Health Lab
Intelligent Health Lab
Medication adherence
JAMIA 2011
Intelligent Health Lab
Intelligent Health Lab
Intelligent Health Lab
26
Intelligent Health Lab
Intelligent Health Lab
Decision Support Integration
e.g., Immunization Forecasting
Intelligent Health Lab
Monograph app
e.g., Diabetes
Intelligent Health Lab
Mashups:
e.g., Genomic Medicine: There’s an App for that
 Linkage to external
decision support
services
 Pharmacogenomic
rule sets
 Decision support
for doctors—
associations
Intelligent Health Lab
Collaborators and Implementers
 EMR Vendors
 Payors
 Pharma
 Major tech companies complementing or competing
in the EHR space
 Large-scale health systems
Intelligent Health Lab

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