6. 6
Two factors for the
contribution:
Living matter obeys the same fundamental physical
and chemical laws that govern all matter.
Powerful new research techniques are discovered.
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8. 8
What is Biochemistry ?
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9. 9
Goals of Biochemistry
Describe structure, organization, function of cells in
molecular terms.
Structural Chemistry
Metabolism
Molecular Genetics
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10. 10
Roots of Biochemistry (Figure 1.3)
Wohler's synthesis of urea
Buchners' fermentation of sugar from yeast extracts
Sumner's crystallization of urease
Flemming's discovery of chromosomes
Mendel's characterization of genes
Miescher's isolation of nucleic acids
Watson and Crick's structure of DNA
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12. 12
Biochemistry as a Discipline and
an interdisciplinary science :
Organic chemistry
Biophysics
Medical research
Nutrition
Microbiology
Physiology
Cell biology
genetics
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13. Biochemistry as a Chemical Science
13
Amino acids
Sugars
Lipids
Nucleotides
Vitamins
Hormones
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14. 14
Chemical Elements of Living
Matter
(Figure 1.4, Table 1.1)
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21. Biochemistry as a Biological Science
21
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22. Distinguishing Characteristics of Living Matter
22
Constant renewal of a highly ordered structure
accompanied by an increase in complexity of that
structure
Overcoming entropy requires energy
Life is self-replicating
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23. 23
Unit of Biological Organization:
The Cell (Figure 1.8, Figure 1.9)
Prokaryotes (Table 1.2)
Eubacteria
Archaebacteria
Eukaryotes
(Compartmentalization of organelles)
(Figure 1.11, Figure 1.13)
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