Archer USMLE step 3 dermatology lecture notes. These lecture notes are samples and are intended for use with Archer video lectures. For video lectures, please log in at http://www.ccsworkshop.com/Pay_Per_View.html

1. Infectious Diseases Archer Online USMLE Reviews www.CcsWorkshop.com All rights reserved Archer Slides are intended for use with Archer USMLE step 3 video lectures. Hence, most slides are very brief summaries of the concepts which will be addressed in a detailed way with focus on High-yield concepts in the Video lectures. These slides are only SAMPLES

2. Antibiotics An Overview

5. Skin and Soft Tissue Infections Impetigo Cellulitis Necrotizing Fascitis

22. Ecthyma Gangrenosum

23. Sexually Transmitted Diseases

24. Syphilis Approach

33. Genital Lesions – Differential Diagnosis Disorder or disease Characteristics of genital lesion Etiology Primary syphilis: chancre Solitary, painless ulcer with indurated border Treponema pallidum Secondary syphilis: condyloma latum Slightly raised or flat, round or oval papules covered by gray exudate T. pallidum Genital herpes Cluster of shallow, small, painful ulcers on a red base Herpes simplex virus Chancroid Painful ulcers with sharp, undermined borders + tender lymphadenopathy Haemophilus ducreyi Venereal warts Soft, usually painless skin-colored or red papules Human papillomavirus Lymphogranuloma venereum: primary stage Painless papule , shallow erosion, or ulcer ; may be multiple or single ( Bubos or unilateral massive inguinal nodes will be helpful in differentiating it from syphilitic chancre) Chlamydia trachomatis

52. Genital warts

57. What are these?

62. Treatment Approach

65. Gonorrhea

78. HIV infection High-yield topics

86. Progressive Multifocal Leucoencephalopathy Cause : Papova virus JC c/f : Dementia a common presenting symptom. Other c/f - hemiparesis, aphasia, dysarthria Dx : MRI/ CT. If +ve for white matter lesions, next step is CSF analysis for JC virus by PCR Rx – HAART

89. Lyme disease

96. Meningitis Refer Neurology Lecture

99. Meningitis

101. Meningitis – Emperical therapy Predisposing Factor AGE Common Bacterial Pathogens Antimicrobial Rx <1 month Streptococcus agalactiae, Escherichia coli, Listeria monocytogenes, Klebsiella species Ampicillin plus cefotaxime or ampicillin plus an aminoglycoside 1 - 23 months Streptococcus pneumoniae , Neisseria meningitidis, S. agalactiae, Haemophilus influenzae, E. coli Vancomycin plus a third-generation cephalosporin 2- 50 years N . meningitidis, S. pneumoniae Vancomycin plus a third-generation cephalosporin >50 years S. pneumoniae, N. meningitidis, L. monocytogenes , aerobic gram-negative bacilli Vancomycin plus ampicillin plus a third-generation cephalosporin

102. Meningitis – Emperical therapy Predisposing Factor HEAD TRAUMA Common Bacterial Pathogens Antimicrobial Rx Basilar skull fracture S. pneumoniae, H. influenzae, group A -hemolytic streptococci Vancomycin plus a third-generation cephalosporin Penetrating trauma Staphylococcus aureus, coagulase-negative staphylococci (especially Staphylococcus epidermidis), aerobic gram-negative bacilli (including Pseudomonas aeruginosa ) Vancomycin plus cefepime, vancomycin plus ceftazidime, or vancomycin plus meropenem  YOU ARE Adding an antipseudomonal antibiotic. Postneurosurgery Aerobic gram-negative bacilli (including P. aeruginosa ), S . aureus , coagulase-negative staphylococci (especially S. epidermidis) Vancomycin plus cefepime, vancomycin plus ceftazidime, or vancomycin plus meropenem CSF shunt Coagulase-negative staphylococci (especially S. epidermidis), S. aureus, aerobic gram-negative bacilli (including P. aeruginosa ), Propionibacterium acnes Vancomycin plus cefepime,c vancomycin plus ceftazidime,c or vancomycin plus meropenem

103. Pneumonias Pulmonology

104. UTIs Nephrology

105. Catheter Related Infections Indwelling catheters  suspect candida. R/o endophthalmitis in candida sepsis, get Ophthal consult If catheter site looks infected  remove catheter. Do not use same site.

110. Immune Reconstitution Syndrome