Opiates

OPIATES Nina Bellio, Frank Chung, Emily Flynn, and Jane Qu

The Human Face of Opiate Addiction http://www.youtube.com/watch?v=KGYjcNOOhKw&NR=1

What are Opiates? ,[object Object],[object Object],http://www.lib.fit.edu/pubs/librarydisplays/arts/poppy.jpg

History ,[object Object],[object Object],[object Object],[object Object]

Opium Wars ,[object Object],[object Object],[object Object],http://www.emsc.nysed.gov/ciai/socst/ghgonline/turnpoint/images/content/tp45/hong.jpg

Where Opiates Come From ,[object Object],[object Object],[object Object],http://www.rehab-international.org/wp-content/uploads/2008/01/opium.thumbnail.jpg

Creation: Heroin ,[object Object],[object Object],[object Object],[object Object],[object Object],http://www.justthinktwice.com/images/pic_heroine3.jpg

How Opiates Feel ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Morphine ,[object Object],[object Object],http://z.about.com/d/chemistry/1/7/f/e/morphine.jpg http://www.drugs-forum.com/opiate-chemistry.html http://www.thetoadband.com/Toad/Toad/Images/Morphine_sulfate2.jpg

Heroin ,[object Object],[object Object],[object Object],http://img.freebase.com/api/trans/image_thumb/wikipedia/images/commons_id/1017373?maxheight=510&mode=fit&maxwidth=510 http://www.drugs-forum.com/opiate-chemistry.html

Codeine ,[object Object],[object Object],http://upload.wikimedia.org/wikipedia/commons/e/ed/Codeine.png http://www.drugs-forum.com/opiate-chemistry.html

Vicodin (Hydrocodone) ,[object Object],[object Object],[object Object],http://upload.wikimedia.org/wikipedia/commons/c/cc/Hydrocodone.svg http://media.canada.com/8975269b-0529-4353-a446-596d133824d2/cnsphoto-strachan-house.jpg

Prescription Opiates ,[object Object],[object Object],[object Object],[object Object],http://babydollsandbeerbottles.files.wordpress.com/2009/08/pill_bottle_and_pills1.jpg http://erstories.net/wp-content/uploads/2008/06/pills-red-and-blue.jpg

What should the doctor do? ,[object Object],[object Object],[object Object],[object Object],[object Object],Source: “Understanding Neurobiology through the study of Addiction.” NIH.

What should the doctor do? ,[object Object],[object Object],[object Object],[object Object],Source: “Understanding Neurobiology through the study of Addiction.” NIH.

How Opiates Work ,[object Object],[object Object],[object Object],[object Object],[object Object]

Opiates And Endorphins ,[object Object],[object Object],http://theoncologist.alphamedpress.org/cgi/content/full/9/6/717/F1

Opiate Receptors ,[object Object],[object Object],[object Object],http://www.nida.nih.gov/pubs/teaching/largegifs/slide-5.gif

G protein Cascade http://theoncologist.alphamedpress.org/content/vol9/issue6/images/large/717_fig2.jpeg

Mu Opiate Receptors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],https://www.scientificamerican.com/article.cfm?id=personal-pain

Pain Pathway ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],http://www.dana.org/uploadedImages/Images/Spotlight_Images/DanaGuide_CH09B05_P167a_spot.jpg

Reward Pathway ,[object Object],[object Object],[object Object],http://www.drugabuse.gov/pubs/teaching/Teaching2/largegifs/slide11.gif

Dopamine Release ,[object Object],[object Object],[object Object],[object Object],[object Object],http://www.drugabuse.gov/pubs/teaching/Teaching2/Teaching4.html

Dopamine Release http://www.cnsforum.com/content/pictures/imagebank/hirespng/moa_heroin_delta_kappa.png

Action of Opiate Agonists ,[object Object],[object Object],http://www.drugabuse.gov/pubs/teaching/Teaching2/Teaching4.html

Effect on the Rest of the Body ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],http://mayoclinic.com/images/image_popup/r7_respiratory.jpg

Effect on the Rest of the Body ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Negative Effects ,[object Object],[object Object],[object Object],[object Object],[object Object],http://www.waukeshafp.org/images/residents_faculty/injection.jpg

Who is the Addict? ,[object Object],[object Object],[object Object],Source: “Understanding Neurobiology through the study of Addiction.” NIH.

Who is the Addict? ,[object Object],[object Object],[object Object],[object Object],Source: “Understanding Neurobiology through the study of Addiction.” NIH.

Tolerance and Dependence ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Addiction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],http://www.drugabuse.gov/pubs/teaching/Teaching2/Teaching4.html

House http://www.youtube.com/watch?v=gQmlsmOZl6c

Drug Addiction Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Treatment ,[object Object],[object Object],Disease Medical Compliance Heroin Addiction ? Hypertension ? Diabetes ?

Treatment ,[object Object],[object Object],[object Object],Source: “Understanding Neurobiology through the study of Addiction.” NIH. Disease Medical Compliance Heroin Addiction 60% Hypertension <30% Diabetes <50%

Behavioral Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Pharmacological Treatments ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Source: “Understanding Neurobiology through the study of Addiction.” NIH.

Treatment: Methadone ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],http://www.drugscope-dworld.org.uk/wip/24/images/methadone.JPG

Methadone problems ,[object Object],[object Object],[object Object],[object Object],http://content.answers.com/main/content/img/oxford/Oxford_Chemistry/0192801015.methadone.1.jpg

Treatment: Naxolone ,[object Object],[object Object],[object Object],[object Object],http://opioids.com/naloxone/naloxone.jpg

Treatment: Buprenorphine ,[object Object],[object Object],[object Object],[object Object],http://www.drugs.com/pro/images/23aa1bb3-cecf-4e62-29bb-48488bb66fc3/xen-0327-1.jpg

How Buprenorphine Works http://www.naabt.org/education/images/Receptors_HiRes.jpg

In the Words of an Ex-Addict ,[object Object]

Social Implications ,[object Object],[object Object],[object Object]

Economic Implications ,[object Object],[object Object],[object Object]

Bibliography ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Bibliography ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Bibliography ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Bibliography ,[object Object],[object Object],[object Object]

Opiates

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Opiates

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