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Dr. V.K.Gupta
Senior Scientist,
Medicine Division
I.V.R.I.IZATNAGAR(UP)
 Heart
Pericarditis
 Effusive
 Fibrinous
 Constrictive
Etiology
 Cattle
 Mannheimia hemolytica
Black disease -if patients survive more than 24 hours
 Sporadic bovine encephalomyelitis
Haemophilus spp., including Histophilus somni
 Tuberculosis
 Pseudomonas aeruginosa
 Mycoplasma spp.
 Klebsiella pneumoniae
 Actinobacillus suis
 Idiopathic effusive (nonseptic) pericarditis
 Traumatic pericarditis
 Development of toxemia and congestive heart failure
 Horses
 Streptococcus spp.- S. equi, S. zooepidemicus and
S. faecalis
 Tuberculosis
 Corynebacterium pseudotuberculosis
 Actinobacillus equuli
 EHV-1 infection
 Idiopathic effusive
Small animals
 Congenital pericardial disorder
Peritoneopericardial diaphragmatic hernia
b/w 4wks & 15 yrs , majority first 4yrs life
Male > female
 Acquired
Bacterial
Fungal – Coccidioidesimmitis
Aspergillusniger
Viral – feline infectious peritonitis
Protozoal – visceral leishmaniasis
Idiopathic – 19-23 %
 Metabolic and/or toxic form
Uremia
Coagulation disorder
 anticoagulant rodent toxicity
Secondary to DIC
Warfarin toxicity
Coagulopathies
 Cardiovascular disorder
CHF
Left atrial perforation
Mitral regurgitation in deg. Valvular disease
 Neoplasia
Cardiac hemangiosarcoma – in right. atrium mostly
61% cause of effus. Pericarditis
Heart base tumor
Associated with ascending artery and main pulmonary
artery
Aortic body tumor
Ectopic thyroid tumor
Breed predis.- english bulldog, boxer, boston terrier ,
In chronic hypoxia induced hyperplasia and neoplasia
of chemoreceptors
 Mesothelioma
 diffuse neoplasm of the pericardium and other serosal
surfaces
 Lymphosarcoma
 Rhabdomysarcoma
 Fibrosarcoma
 Sheep and goats
Pasteurellosis
Staphylococcus aureus
Mycoplasma spp.
 Pigs
 Pasteurellosis
Mycoplasma hyorhinis
 Haemophilus spp. - Glasser's disease and
pleuropneumonia
Streptococcus spp.
 Salmonellosis
Pathogenesis
 In the early stages
Inflammation Hyperemia Deposition of
Fibrinous Exudate Friction Sound Muffling of
The Heart Sounds Atria and Right Ventricle
Compression CHF
Toxemia
Anaerobic bacteria gas-production washing
machine sound of fluid splashing with each heart beat
 In the recovery stag
 Reabsorption of fluid adhesive pericarditis
 In suppurative pericarditis complete adhesion
CLINICAL FINDINGS
Clinical signs
 Lethargy
 Resp. difficulty
 Collapse
 Reduced appetite
 Vomiting
 Abd. Distension
 Polydipsia
 Weakness
 Coughing
Pulsus paradoxus
 Associated with cardiac tamponade
 Phasic variation in pulse quality with respiration
 ≥10 mm Hg decrease in systolic arterial BP with
inspiration during normal breathing
 LV stroke volume and systemic arterial BP decreases
with inspiration
Diagnosis
 Thoracic radiograph
 Echocardiography
 Echo
Echocardiograph
 Hemangiosarcoma
Electrocardiography
 Electrical alternans is evident on this lead II
electrocardiogram from a 10-year-old male Bulldog with a
large pericardial effusion. Note also the small voltage QRS
complexes
 Sinus Tachycardia (heart rate about 170 beats/min)
Hematology and biochemistry
 Hemangiosarcoma
Anemia , nucleated RBC .,
Schistocyte , acanthocyte &
thrombocytopenia
Increased serum cardio tropin I
 Increased liver enzyme
 Mild prerenal azotemia
 In FIP – neutrophilia , lymphocytopenia ,
hyperglobulinemia
 Ascites fluid- protein transudate
Diff. diagnosis
 Other cause of Rt. CHF – DCM, tricuspid dysplasia ,
ascites( hepatic disease , Abd. Neoplasia)
 Other cause of muffled heart sound- pleural effusion,
thoracic mass , diaphragmatic hernia
 Other cuase of low voltage complexe- pleural effusion,
obesity, hypothyroidism
 Other cause of cardiac enlargement – DCM, tricuspid
dysplasia, PPDH
Treatment & prognosis
 Important to differentiate cardiac tamponade from
other causes of right-sided CHF because the treatment
is very different.
 Positive inotropic drugs do not ameliorate the signs of
tamponade; diuretics and vasodilators can further
reduce cardiac output and exacerbate hypotension and
shock
 Pericardiocentesis is the immediate treatment of
choice, and it also provides diagnostic information
 Most signs of CHF resolve after pericardial fluid is
removed
 Pericardial effusions secondary to other diseases that
cause CHF, congenital malformations, or
hypoalbuminemia do not usually cause tamponade
and often resolve with management of the underlying
condition.
 Antibacterial treatment of the specific infection
should be undertaken if possible on the basis of
susceptibility on organisms cultured from the
pericardial fluid
 The prognosis varies with the etiological agent but it is
generally grave in cases of septic pericarditis
 Fifth rib resection and pericardial marsupialization
 Pericardial drainage and intrapericardial lavage
 Antimicrobial administration
 Recurrent effusion that does not respond to repeated
pericardiocentesis and anti inflammatory therapy is
usually treated by subtotal pericardiectomy.
 Removal of the pericardium ventral to the phrenic
nerves allows pericardial fluid drainage to the larger
absorptive surface of the pleural space
 Neoplastic pericardial effusions are also drained to
relieve cardiac tamponade
 Surgical therapy is likely to be more effective than
continuous drainage with an indwelling pericardial
catheter, and it also allows removal of penetrating
foreign bodies
PERICARDIOCENTESIS
 Done immediately in animals with cardiac tamponade.
 diuretics or vasodilators without pericardiocentesis
may cause further hypotension and cardiogenic shock.
 Pericardiocentesis should be performed under
ultrasonographic guidance and with ECG monitoring.
Pericarditis in animals
Pericarditis in animals
Pericarditis in animals

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Pericarditis in animals

  • 1. Dr. V.K.Gupta Senior Scientist, Medicine Division I.V.R.I.IZATNAGAR(UP)
  • 3.
  • 5. Etiology  Cattle  Mannheimia hemolytica Black disease -if patients survive more than 24 hours  Sporadic bovine encephalomyelitis Haemophilus spp., including Histophilus somni  Tuberculosis  Pseudomonas aeruginosa  Mycoplasma spp.  Klebsiella pneumoniae  Actinobacillus suis  Idiopathic effusive (nonseptic) pericarditis
  • 6.  Traumatic pericarditis  Development of toxemia and congestive heart failure
  • 7.  Horses  Streptococcus spp.- S. equi, S. zooepidemicus and S. faecalis  Tuberculosis  Corynebacterium pseudotuberculosis  Actinobacillus equuli  EHV-1 infection  Idiopathic effusive
  • 8. Small animals  Congenital pericardial disorder Peritoneopericardial diaphragmatic hernia b/w 4wks & 15 yrs , majority first 4yrs life Male > female  Acquired Bacterial Fungal – Coccidioidesimmitis Aspergillusniger Viral – feline infectious peritonitis Protozoal – visceral leishmaniasis Idiopathic – 19-23 %
  • 9.  Metabolic and/or toxic form Uremia Coagulation disorder  anticoagulant rodent toxicity Secondary to DIC Warfarin toxicity Coagulopathies  Cardiovascular disorder CHF Left atrial perforation Mitral regurgitation in deg. Valvular disease
  • 10.  Neoplasia Cardiac hemangiosarcoma – in right. atrium mostly 61% cause of effus. Pericarditis Heart base tumor Associated with ascending artery and main pulmonary artery Aortic body tumor Ectopic thyroid tumor Breed predis.- english bulldog, boxer, boston terrier , In chronic hypoxia induced hyperplasia and neoplasia of chemoreceptors
  • 11.  Mesothelioma  diffuse neoplasm of the pericardium and other serosal surfaces  Lymphosarcoma  Rhabdomysarcoma  Fibrosarcoma
  • 12.  Sheep and goats Pasteurellosis Staphylococcus aureus Mycoplasma spp.  Pigs  Pasteurellosis Mycoplasma hyorhinis  Haemophilus spp. - Glasser's disease and pleuropneumonia Streptococcus spp.  Salmonellosis
  • 13. Pathogenesis  In the early stages Inflammation Hyperemia Deposition of Fibrinous Exudate Friction Sound Muffling of The Heart Sounds Atria and Right Ventricle Compression CHF Toxemia Anaerobic bacteria gas-production washing machine sound of fluid splashing with each heart beat
  • 14.  In the recovery stag  Reabsorption of fluid adhesive pericarditis  In suppurative pericarditis complete adhesion
  • 16. Clinical signs  Lethargy  Resp. difficulty  Collapse  Reduced appetite  Vomiting  Abd. Distension  Polydipsia  Weakness  Coughing
  • 17. Pulsus paradoxus  Associated with cardiac tamponade  Phasic variation in pulse quality with respiration  ≥10 mm Hg decrease in systolic arterial BP with inspiration during normal breathing  LV stroke volume and systemic arterial BP decreases with inspiration
  • 23. Electrocardiography  Electrical alternans is evident on this lead II electrocardiogram from a 10-year-old male Bulldog with a large pericardial effusion. Note also the small voltage QRS complexes  Sinus Tachycardia (heart rate about 170 beats/min)
  • 24. Hematology and biochemistry  Hemangiosarcoma Anemia , nucleated RBC ., Schistocyte , acanthocyte & thrombocytopenia Increased serum cardio tropin I  Increased liver enzyme  Mild prerenal azotemia  In FIP – neutrophilia , lymphocytopenia , hyperglobulinemia  Ascites fluid- protein transudate
  • 25. Diff. diagnosis  Other cause of Rt. CHF – DCM, tricuspid dysplasia , ascites( hepatic disease , Abd. Neoplasia)  Other cause of muffled heart sound- pleural effusion, thoracic mass , diaphragmatic hernia  Other cuase of low voltage complexe- pleural effusion, obesity, hypothyroidism  Other cause of cardiac enlargement – DCM, tricuspid dysplasia, PPDH
  • 26. Treatment & prognosis  Important to differentiate cardiac tamponade from other causes of right-sided CHF because the treatment is very different.  Positive inotropic drugs do not ameliorate the signs of tamponade; diuretics and vasodilators can further reduce cardiac output and exacerbate hypotension and shock  Pericardiocentesis is the immediate treatment of choice, and it also provides diagnostic information  Most signs of CHF resolve after pericardial fluid is removed
  • 27.  Pericardial effusions secondary to other diseases that cause CHF, congenital malformations, or hypoalbuminemia do not usually cause tamponade and often resolve with management of the underlying condition.  Antibacterial treatment of the specific infection should be undertaken if possible on the basis of susceptibility on organisms cultured from the pericardial fluid  The prognosis varies with the etiological agent but it is generally grave in cases of septic pericarditis
  • 28.  Fifth rib resection and pericardial marsupialization  Pericardial drainage and intrapericardial lavage  Antimicrobial administration  Recurrent effusion that does not respond to repeated pericardiocentesis and anti inflammatory therapy is usually treated by subtotal pericardiectomy.  Removal of the pericardium ventral to the phrenic nerves allows pericardial fluid drainage to the larger absorptive surface of the pleural space  Neoplastic pericardial effusions are also drained to relieve cardiac tamponade
  • 29.  Surgical therapy is likely to be more effective than continuous drainage with an indwelling pericardial catheter, and it also allows removal of penetrating foreign bodies
  • 30. PERICARDIOCENTESIS  Done immediately in animals with cardiac tamponade.  diuretics or vasodilators without pericardiocentesis may cause further hypotension and cardiogenic shock.  Pericardiocentesis should be performed under ultrasonographic guidance and with ECG monitoring.